CA2981768C - Bioconjugates of heterocyclic compounds - Google Patents

Bioconjugates of heterocyclic compounds Download PDF

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Publication number
CA2981768C
CA2981768C CA2981768A CA2981768A CA2981768C CA 2981768 C CA2981768 C CA 2981768C CA 2981768 A CA2981768 A CA 2981768A CA 2981768 A CA2981768 A CA 2981768A CA 2981768 C CA2981768 C CA 2981768C
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CA
Canada
Prior art keywords
sam
date
sah
date received
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2981768A
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English (en)
French (fr)
Other versions
CA2981768A1 (en
Inventor
Xiujuan Hao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taizhou Huifeng Hetai Biotechnology Co Ltd
Original Assignee
Taizhou Huifeng Hetai Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Taizhou Huifeng Hetai Biotechnology Co Ltd filed Critical Taizhou Huifeng Hetai Biotechnology Co Ltd
Publication of CA2981768A1 publication Critical patent/CA2981768A1/en
Application granted granted Critical
Publication of CA2981768C publication Critical patent/CA2981768C/en
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G01N33/6815—Assays for specific amino acids containing sulfur, e.g. cysteine, cystine, methionine, homocysteine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2981768A 2015-04-06 2016-04-06 Bioconjugates of heterocyclic compounds Active CA2981768C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562143790P 2015-04-06 2015-04-06
US62/143,790 2015-04-06
US15/091,544 2016-04-05
US15/091,544 US10138267B2 (en) 2015-04-06 2016-04-05 Bioconjugates of heterocyclic compounds
PCT/US2016/026279 WO2016164504A1 (en) 2015-04-06 2016-04-06 Bioconjugates of heterocyclic compounds

Publications (2)

Publication Number Publication Date
CA2981768A1 CA2981768A1 (en) 2016-10-13
CA2981768C true CA2981768C (en) 2022-03-08

Family

ID=57015829

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2981768A Active CA2981768C (en) 2015-04-06 2016-04-06 Bioconjugates of heterocyclic compounds

Country Status (7)

Country Link
US (1) US10138267B2 (https=)
EP (2) EP3337804A4 (https=)
JP (2) JP7327898B2 (https=)
CN (1) CN108391432B (https=)
AU (1) AU2016246603B2 (https=)
CA (1) CA2981768C (https=)
WO (1) WO2016164504A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10138267B2 (en) * 2015-04-06 2018-11-27 Hunan Skyworld Biotechnologies Co. Ltd. Bioconjugates of heterocyclic compounds
CA3138608A1 (en) 2019-05-01 2020-11-05 Commonwealth Scientific And Industrial Research Organisation Immunosensor
CN111499724A (zh) * 2020-04-15 2020-08-07 上海领潮生物新材料有限公司 一种s-腺苷同型半胱氨酸-鸡卵白蛋白偶联物的制备方法
CN116367832B (zh) * 2020-10-12 2026-02-17 苏州华明道康生物医药有限公司 取代的杂芳基化合物及其用途
CN112924427B (zh) * 2021-02-02 2022-07-08 中国农业科学院特产研究所 一种消除植物组织自体荧光的方法
CN114315980B (zh) * 2021-12-30 2023-04-28 湖南中晟全肽生化有限公司 抑制il-17a与il-17受体结合的多肽及其应用
WO2024059841A2 (en) * 2022-09-16 2024-03-21 Early Is Good, Inc. Analyte detection and quantification

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0035317A1 (en) 1980-03-04 1981-09-09 Yoshiaki Nagaura Method for the manufacture of lens-like articles
DE3822750A1 (de) 1988-07-05 1990-01-11 Boehringer Mannheim Gmbh Verfahren zur bestimmung einer spezifisch bindefaehigen substanz
US5202423A (en) 1988-07-08 1993-04-13 Wallac Oy Terpyridine derivatives
FR2664699B1 (fr) 1990-07-13 1995-08-18 Cis Bio Int Procede d'amplification du signal d'emission d'un compose luminescent.
FI88654C (fi) 1991-03-15 1993-06-10 Datacity Center Oy Fluorescenshoejningsmetod
FI91449C (fi) 1992-10-29 1994-06-27 Wallac Oy Menetelmä biologisen aineen määrittämiseksi in situ
WO2009078876A1 (en) 2007-12-18 2009-06-25 Bellbrook Labs, Llc Assay method for group transfer reactions
US8344115B2 (en) * 2008-04-21 2013-01-01 Chan-Sui Pang, legal representative Immunoassay for specific determination of S-adenosylmethionine and analogs thereof in biological samples
US8268264B2 (en) 2009-02-09 2012-09-18 Caprotec Bioanalytics Gmbh Devices, systems and methods for separating magnetic particles
CN104046682B (zh) * 2013-03-13 2015-12-09 苏州博泰安生物科技有限公司 同型半胱氨酸的检测方法及其诊断试剂盒
US9958447B2 (en) * 2013-03-15 2018-05-01 Hunan Skyworld Biotechnologies Co Immunoassay of S-adenosylmethionine in personalized medicine and health or cancer evaluation
US10138267B2 (en) 2015-04-06 2018-11-27 Hunan Skyworld Biotechnologies Co. Ltd. Bioconjugates of heterocyclic compounds
US10067126B2 (en) * 2015-05-25 2018-09-04 Hunan SkyWorld Biotechnologies Co. LTD Use of fluorescence for the quick and easy determination of s-adenosylmethionine, s-adenosylhomocysteine and homocysteine

Also Published As

Publication number Publication date
CN108391432B (zh) 2022-03-22
US20160291014A1 (en) 2016-10-06
JP7327898B2 (ja) 2023-08-16
JP7344928B2 (ja) 2023-09-14
JP2021152027A (ja) 2021-09-30
WO2016164504A1 (en) 2016-10-13
EP4219518A2 (en) 2023-08-02
CN108391432A (zh) 2018-08-10
EP3337804A1 (en) 2018-06-27
EP3337804A4 (en) 2019-02-20
JP2018516858A (ja) 2018-06-28
AU2016246603B2 (en) 2019-08-15
US10138267B2 (en) 2018-11-27
AU2016246603A1 (en) 2017-11-23
CA2981768A1 (en) 2016-10-13

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