CA2973771A1 - Glypican epitopes and uses thereof - Google Patents
Glypican epitopes and uses thereofInfo
- Publication number
- CA2973771A1 CA2973771A1 CA2973771A CA2973771A CA2973771A1 CA 2973771 A1 CA2973771 A1 CA 2973771A1 CA 2973771 A CA2973771 A CA 2973771A CA 2973771 A CA2973771 A CA 2973771A CA 2973771 A1 CA2973771 A1 CA 2973771A1
- Authority
- CA
- Canada
- Prior art keywords
- epitope
- seq
- variant
- segment
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/303—Liver or Pancreas
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
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Landscapes
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| PCT/AU2015/000019 WO2016112423A1 (en) | 2015-01-16 | 2015-01-16 | Glypican epitopes and uses thereof |
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| CA2973771A1 true CA2973771A1 (en) | 2016-07-21 |
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| CN107108734B (zh) | 2014-10-23 | 2021-09-14 | 美侬米克国际有限公司 | 单克隆抗gpc-1抗体和其用途 |
| AU2016250900B2 (en) * | 2015-04-20 | 2022-03-17 | GlyTherix Ltd. | Therapeutic antibodies and uses thereof |
| US20200308299A1 (en) * | 2017-04-28 | 2020-10-01 | National University Corporation Kochi University | Anti-gpc-1 antibody |
| AU2020212534A1 (en) * | 2019-01-22 | 2021-07-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | High affinity monoclonal antibodies targeting glypican-1 and methods of use |
| CN111187350A (zh) * | 2019-12-30 | 2020-05-22 | 西安英创生物技术有限公司 | 一种与磷脂酰肌醇蛋白聚糖-1结合的抗原结合蛋白 |
| IT202200021546A1 (it) | 2022-10-19 | 2024-04-19 | Centro Di Riferimento Oncologico Di Aviano | Anticorpo monoclonale anti-GPC1, suoi usi terapeutici e diagnostici |
| WO2025202359A1 (en) * | 2024-03-27 | 2025-10-02 | Adcendo Aps | Anti-gpc1 antibodies and uses thereof |
| WO2025202361A1 (en) * | 2024-03-27 | 2025-10-02 | Adcendo Aps | Anti-gpc1 antibodies and uses thereof |
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| US4356270A (en) | 1977-11-08 | 1982-10-26 | Genentech, Inc. | Recombinant DNA cloning vehicle |
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
| US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
| US5840839A (en) * | 1996-02-09 | 1998-11-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |
| WO1999037764A2 (en) * | 1998-01-27 | 1999-07-29 | Vlaams Interuniversitair Instituut Voor Biotechnologie | New members of the glypican gene family |
| CA2346264A1 (en) * | 1998-10-16 | 2000-04-27 | Regents Of The University Of California | Glypicans for the detection and treatment of human carcinoma |
| US20040226056A1 (en) * | 1998-12-22 | 2004-11-11 | Myriad Genetics, Incorporated | Compositions and methods for treating neurological disorders and diseases |
| EP2208784B1 (en) * | 2001-06-22 | 2013-01-02 | Chugai Seiyaku Kabushiki Kaisha | Cell proliferation inhibitors containing anti-glypican 3 antibody |
| DE602005024502D1 (de) * | 2004-07-09 | 2010-12-16 | Chugai Pharmaceutical Co Ltd | Anti-glypican-3-antikörper |
| US20070087005A1 (en) * | 2005-10-14 | 2007-04-19 | Lazar Gregory A | Anti-glypican-3 antibody |
| US8270389B2 (en) | 2008-08-11 | 2012-09-18 | Marvell International Ltd. | Method of synchronization for low power idle |
| CN102180969B (zh) * | 2011-01-30 | 2013-04-10 | 中国人民解放军军事医学科学院微生物流行病研究所 | 抗肝癌活性单克隆抗体及其应用 |
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2023
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| US20240247037A1 (en) | 2024-07-25 |
| EP3245219B1 (en) | 2020-04-08 |
| EP3245219A1 (en) | 2017-11-22 |
| EP3245219A4 (en) | 2018-06-06 |
| KR20170109584A (ko) | 2017-09-29 |
| DK3245219T3 (da) | 2020-06-29 |
| AU2015376851A1 (en) | 2017-07-27 |
| SG11201705808XA (en) | 2017-08-30 |
| US20210107958A1 (en) | 2021-04-15 |
| JP6735005B2 (ja) | 2020-08-05 |
| JP2018504903A (ja) | 2018-02-22 |
| ES2805085T3 (es) | 2021-02-10 |
| CN107531755B (zh) | 2022-02-25 |
| CN107531755A (zh) | 2018-01-02 |
| WO2016112423A1 (en) | 2016-07-21 |
| AU2015376851B2 (en) | 2020-07-09 |
| US20180002391A1 (en) | 2018-01-04 |
| KR102435383B1 (ko) | 2022-08-24 |
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