CA2972960C - Identification of functional cell states - Google Patents

Identification of functional cell states Download PDF

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Publication number
CA2972960C
CA2972960C CA2972960A CA2972960A CA2972960C CA 2972960 C CA2972960 C CA 2972960C CA 2972960 A CA2972960 A CA 2972960A CA 2972960 A CA2972960 A CA 2972960A CA 2972960 C CA2972960 C CA 2972960C
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cells
cell
tensor
response
agent
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French (fr)
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CA2972960A1 (en
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Bartlomiej Rajwa
T. Vincent Shankey
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ASEDASCIENCES AG
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ASEDASCIENCES AG
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5026—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell morphology
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/30—Prediction of properties of chemical compounds, compositions or mixtures
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/40—Searching chemical structures or physicochemical data
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00—Subject matter not provided for in other groups of this subclass

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Computing Systems (AREA)
  • Physiology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CA2972960A 2014-01-14 2015-01-14 Identification of functional cell states Active CA2972960C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461927247P 2014-01-14 2014-01-14
US61/927,247 2014-01-14
PCT/US2015/011441 WO2015109003A1 (en) 2014-01-14 2015-01-14 Identification of functional cell states

Publications (2)

Publication Number Publication Date
CA2972960A1 CA2972960A1 (en) 2015-07-23
CA2972960C true CA2972960C (en) 2022-01-11

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Family Applications (1)

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CA2972960A Active CA2972960C (en) 2014-01-14 2015-01-14 Identification of functional cell states

Country Status (11)

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US (3) US11137388B2 (enExample)
EP (1) EP3094974B1 (enExample)
JP (1) JP6606100B2 (enExample)
KR (1) KR102413041B1 (enExample)
AU (2) AU2015206520B2 (enExample)
CA (1) CA2972960C (enExample)
DK (1) DK3094974T3 (enExample)
ES (1) ES2728119T3 (enExample)
IL (1) IL246734B (enExample)
SG (1) SG11201705495XA (enExample)
WO (1) WO2015109003A1 (enExample)

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KR102413041B1 (ko) * 2014-01-14 2022-06-23 아세다사이언시즈 아게 기능성 세포 상태의 확인
JP6544600B2 (ja) 2015-02-24 2019-07-17 国立大学法人 東京大学 動的高速高感度イメージング装置及びイメージング方法
WO2017073737A1 (ja) * 2015-10-28 2017-05-04 国立大学法人東京大学 分析装置
US10824693B2 (en) * 2015-12-10 2020-11-03 Reservoir Labs, Inc. Systems and methods for selective expansive recursive tensor analysis
US11205103B2 (en) 2016-12-09 2021-12-21 The Research Foundation for the State University Semisupervised autoencoder for sentiment analysis
US12300357B2 (en) 2016-12-14 2025-05-13 FlowJo, LLC Applied computer technology for management, synthesis, visualization, and exploration of parameters in large multi-parameter data sets
WO2018217933A1 (en) 2017-05-25 2018-11-29 FlowJo, LLC Visualization, comparative analysis, and automated difference detection for large multi-parameter data sets
CN112638529B (zh) 2018-06-13 2023-05-30 新克赛特株式会社 细胞计数的方法和系统
EP4641584A3 (en) 2019-05-14 2025-12-10 University of Pittsburgh - of the Commonwealth System of Higher Education System and method for characterizing cellular phenotypic diversity from multi-parameter cellular and sub-cellular imaging data
WO2021132484A1 (ja) 2019-12-27 2021-07-01 シンクサイト株式会社 フローサイトメータ性能評価方法、及び標準粒子懸濁液
JPWO2021200960A1 (enExample) 2020-04-01 2021-10-07
CN121476024A (zh) 2020-04-01 2026-02-06 兴科尚株式会社 流式细胞仪
EP4189065A4 (en) * 2020-07-30 2024-08-28 Allen Institute SYSTEMS, DEVICES AND METHODS FOR SCREENING COMPOUNDS USING PREDICTIVE LABELING
WO2023009513A1 (en) 2021-07-26 2023-02-02 Asedasciences Ag Improved methods for identification of functional cell states
WO2023056481A1 (en) * 2021-10-01 2023-04-06 CAP Diagnostics, LLC, dba Pathnostics Automated methods and systems for rapid identification of target particles
US12105081B2 (en) 2021-10-20 2024-10-01 Travera, Inc. Treatment response assessment using normalized single cell measurements
CN117517288A (zh) * 2022-11-15 2024-02-06 上海交通大学 一种基于多光谱集的拉曼光谱相似性评估方法
CN121359212A (zh) 2023-01-23 2026-01-16 阿斯达科学股份公司 增强人机交互系统

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US5544650A (en) * 1988-04-08 1996-08-13 Neuromedical Systems, Inc. Automated specimen classification system and method
CA2153344A1 (en) * 1993-01-08 1994-07-21 John A. Maples Method of using preserved control cells in the calibration of fluorescent and light scatter measurements
CA2196496A1 (en) 1997-01-31 1998-07-31 Stephen William Watson Michnick Protein fragment complementation assay for the detection of protein-protein interactions
US7166424B2 (en) 1998-02-02 2007-01-23 Odyssey Thera Inc. Fragments of fluorescent proteins for protein fragment complementation assays
US20050221280A1 (en) * 1998-02-02 2005-10-06 Odyssey Thera, Inc. Protein-protein interactions for pharmacological profiling
US6801859B1 (en) 1998-12-23 2004-10-05 Rosetta Inpharmatics Llc Methods of characterizing drug activities using consensus profiles
US6998249B1 (en) * 1999-09-27 2006-02-14 Pharmacia & Upjohn Company Toxicity screening method
JP4798921B2 (ja) 2000-03-06 2011-10-19 バイオシーク インコーポレーティッド 機能相同性スクリーニング
WO2001092859A1 (en) * 2000-06-02 2001-12-06 Medicometrics Aps Method and system for classifying a biological sample
US7146349B2 (en) 2000-11-06 2006-12-05 International Business Machines Corporation Network for describing multimedia information
US20070087344A1 (en) 2003-04-23 2007-04-19 Bioseek, Inc. Methods for characterizing signaling pathways and compounds that interact therewith
WO2004094992A2 (en) 2003-04-23 2004-11-04 Bioseek, Inc. Methods for analysis of biological dataset profiles
WO2008134593A1 (en) * 2007-04-25 2008-11-06 President And Fellows Of Harvard College Molecular circuits
US20130226469A1 (en) 2008-04-01 2013-08-29 Purdue Research Foundation Gate-free flow cytometry data analysis
WO2009146036A2 (en) * 2008-04-01 2009-12-03 Purdue Research Foundation Quantification of differences between measured values and statistical validation based on the differences
KR102413041B1 (ko) * 2014-01-14 2022-06-23 아세다사이언시즈 아게 기능성 세포 상태의 확인

Also Published As

Publication number Publication date
EP3094974B1 (en) 2019-02-27
AU2015206520A1 (en) 2016-07-14
WO2015109003A1 (en) 2015-07-23
IL246734B (en) 2019-06-30
EP3094974A1 (en) 2016-11-23
US11137388B2 (en) 2021-10-05
IL246734A0 (en) 2016-08-31
ES2728119T3 (es) 2019-10-22
KR102413041B1 (ko) 2022-06-23
US20210364499A1 (en) 2021-11-25
US11867690B2 (en) 2024-01-09
AU2021204419A1 (en) 2021-07-22
US20150198584A1 (en) 2015-07-16
HK1231553A1 (en) 2017-12-22
US20160370350A1 (en) 2016-12-22
DK3094974T3 (da) 2019-05-27
CA2972960A1 (en) 2015-07-23
JP2017505140A (ja) 2017-02-16
KR20160110444A (ko) 2016-09-21
AU2015206520B2 (en) 2021-07-22
SG11201705495XA (en) 2017-08-30
JP6606100B2 (ja) 2019-11-13

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