CA2969716C - Hydrogel drug delivery implants - Google Patents

Hydrogel drug delivery implants Download PDF

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Publication number
CA2969716C
CA2969716C CA2969716A CA2969716A CA2969716C CA 2969716 C CA2969716 C CA 2969716C CA 2969716 A CA2969716 A CA 2969716A CA 2969716 A CA2969716 A CA 2969716A CA 2969716 C CA2969716 C CA 2969716C
Authority
CA
Canada
Prior art keywords
hydrogel
particles
precursors
biodegradable material
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2969716A
Other languages
English (en)
French (fr)
Other versions
CA2969716A1 (en
Inventor
Peter Jarrett
Rami EL-HAYEK
Amarpreet S. Sawhney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incept LLC
Original Assignee
Incept LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incept LLC filed Critical Incept LLC
Publication of CA2969716A1 publication Critical patent/CA2969716A1/en
Application granted granted Critical
Publication of CA2969716C publication Critical patent/CA2969716C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2969716A 2014-12-10 2015-12-10 Hydrogel drug delivery implants Active CA2969716C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462089994P 2014-12-10 2014-12-10
US62/089,994 2014-12-10
PCT/US2015/064975 WO2016094646A1 (en) 2014-12-10 2015-12-10 Hydrogel drug delivery implants

Publications (2)

Publication Number Publication Date
CA2969716A1 CA2969716A1 (en) 2016-06-16
CA2969716C true CA2969716C (en) 2023-12-19

Family

ID=55070156

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2969716A Active CA2969716C (en) 2014-12-10 2015-12-10 Hydrogel drug delivery implants

Country Status (8)

Country Link
US (2) US20160166504A1 (enExample)
EP (2) EP3858329A1 (enExample)
JP (2) JP7092502B2 (enExample)
KR (1) KR20170117384A (enExample)
CN (2) CN120501693A (enExample)
AU (1) AU2015360469B2 (enExample)
CA (1) CA2969716C (enExample)
WO (1) WO2016094646A1 (enExample)

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CN113367883A (zh) * 2021-06-08 2021-09-10 复旦大学附属眼耳鼻喉科医院 一种原位成胶个体化配适的角膜绷带镜
US12582767B2 (en) 2021-12-30 2026-03-24 Taiyo Weber Compressible, minimally invasive implants and related systems and methods
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Also Published As

Publication number Publication date
CN107205922A (zh) 2017-09-26
AU2015360469A1 (en) 2017-06-22
JP2017537130A (ja) 2017-12-14
EP3229779B1 (en) 2021-02-03
JP2021046429A (ja) 2021-03-25
CN120501693A (zh) 2025-08-19
JP7092502B2 (ja) 2022-06-28
CA2969716A1 (en) 2016-06-16
KR20170117384A (ko) 2017-10-23
US20260060921A1 (en) 2026-03-05
AU2015360469B2 (en) 2021-03-25
EP3858329A1 (en) 2021-08-04
EP3229779A1 (en) 2017-10-18
WO2016094646A1 (en) 2016-06-16
US20160166504A1 (en) 2016-06-16

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