JP7092502B2 - ハイドロゲル薬物送達インプラント - Google Patents

ハイドロゲル薬物送達インプラント Download PDF

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Publication number
JP7092502B2
JP7092502B2 JP2017531184A JP2017531184A JP7092502B2 JP 7092502 B2 JP7092502 B2 JP 7092502B2 JP 2017531184 A JP2017531184 A JP 2017531184A JP 2017531184 A JP2017531184 A JP 2017531184A JP 7092502 B2 JP7092502 B2 JP 7092502B2
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hydrogel
particles
therapeutic agent
precursor
functional group
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JP2017537130A (ja
JP2017537130A5 (enExample
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ピーター・ジャレット
ラミ・エル－ハイエク
アマルプリート・エス・ソーニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2017531184A 2014-12-10 2015-12-10 ハイドロゲル薬物送達インプラント Active JP7092502B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462089994P 2014-12-10 2014-12-10
US62/089,994 2014-12-10
PCT/US2015/064975 WO2016094646A1 (en) 2014-12-10 2015-12-10 Hydrogel drug delivery implants

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020201207A Division JP2021046429A (ja) 2014-12-10 2020-12-03 ハイドロゲル薬物送達インプラント

Publications (3)

Publication Number Publication Date
JP2017537130A JP2017537130A (ja) 2017-12-14
JP2017537130A5 JP2017537130A5 (enExample) 2019-01-24
JP7092502B2 true JP7092502B2 (ja) 2022-06-28

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Family Applications (2)

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JP2017531184A Active JP7092502B2 (ja) 2014-12-10 2015-12-10 ハイドロゲル薬物送達インプラント
JP2020201207A Pending JP2021046429A (ja) 2014-12-10 2020-12-03 ハイドロゲル薬物送達インプラント

Family Applications After (1)

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JP2020201207A Pending JP2021046429A (ja) 2014-12-10 2020-12-03 ハイドロゲル薬物送達インプラント

Country Status (8)

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US (2) US20160166504A1 (enExample)
EP (2) EP3858329A1 (enExample)
JP (2) JP7092502B2 (enExample)
KR (1) KR20170117384A (enExample)
CN (2) CN120501693A (enExample)
AU (1) AU2015360469B2 (enExample)
CA (1) CA2969716C (enExample)
WO (1) WO2016094646A1 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2964194B1 (en) 2013-03-05 2022-08-17 University of Pittsburgh - Of the Commonwealth System of Higher Education Thermoresponsive hydrogel containing polymer microparticles for noninvasive ocular drug delivery
US20220118416A1 (en) * 2020-10-18 2022-04-21 Pathak Holdings Llc Crosslinked multilayered material compositions, methods for their preparation and applications thereof
US12629345B2 (en) 2013-03-14 2026-05-19 Pathak Holdings Llc Methods, compositions, and devices for drug / live cell microarrays
MX2017007873A (es) 2014-12-15 2017-11-06 Univ Johns Hopkins Formulaciones de sunitinib y metodos para uso de las mismas en el tratamiento de trastornos oculares.
EP3288626B8 (en) 2015-04-27 2025-12-10 Tulavi Therapeutics, Inc. Substances and compositions for use in blocking nerve regeneration
WO2016183296A1 (en) 2015-05-12 2016-11-17 Incept, Llc Drug delivery from hydrogels
WO2017062770A1 (en) 2015-10-08 2017-04-13 Silverberg Noah Punctal plug and bioadhesives
US10441548B2 (en) 2015-11-12 2019-10-15 Graybug Vision, Inc. Aggregating microparticles for medical therapy
AU2016361579B2 (en) 2015-11-25 2022-08-04 Incept, Llc Shape changing drug delivery devices and methods
WO2017139487A1 (en) 2016-02-09 2017-08-17 Northwind Medical, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
US20190099365A1 (en) * 2016-03-22 2019-04-04 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Thermoresponsive hydrogel containing polymer microparticles for noninvasive ocular biologic delivery
AU2017290353B2 (en) 2016-06-29 2023-05-18 Tulavi Therapeutics, Inc. Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system
WO2018017899A1 (en) * 2016-07-20 2018-01-25 Emory University Formulations for the suprachoroidal space of an eye and methods
KR102814241B1 (ko) * 2016-09-23 2025-05-29 인셉트, 엘엘씨 전안방내 약물 전달 데포
WO2018067882A1 (en) 2016-10-05 2018-04-12 Titan Pharmaceuticals, Inc. Implantable devices for drug delivery with reduced burst release
MX2019013363A (es) 2017-05-10 2020-01-13 Graybug Vision Inc Microparticulas de liberacion extendida y suspensiones de las mismas para terapia medica.
WO2019043699A1 (en) 2017-08-30 2019-03-07 Hadasit Medical Research Services And Development Ltd. DEVICES, KITS AND METHODS FOR REDUCING AND / OR PREVENTING INTRA-ABDOMINAL ADHESIONS
WO2019088292A1 (ja) * 2017-11-06 2019-05-09 コニカミノルタ株式会社 ハイドロゲル粒子およびその製造方法、ハイドロゲル粒子を内包する細胞または細胞構造体、ハイドロゲル粒子を用いた細胞活性の評価方法、並びにハイドロゲル粒子の徐放性製剤としての使用
US20210221962A1 (en) * 2018-02-20 2021-07-22 Advanced Aesthetic Technologies, Inc. High concentration hydrogels and related methods
AU2019299519B2 (en) 2018-07-02 2025-03-06 Incept Llc Methods and devices for in situ formed nerve cap
US20210315587A1 (en) 2018-07-02 2021-10-14 Tulavi Therapeutics, Inc. Methods and devices for in situ formed nerve cap with rapid release
CN112752568A (zh) * 2018-08-15 2021-05-04 微思有限公司 具有用于流动路径修饰的可生物降解材料的持续释出部件及相应的药物输送装置
US12599577B2 (en) 2018-11-16 2026-04-14 University of Pittsburgh—of the Commonwealth System of Higher Education Thermoresponsive gel eye drop for ocular delivery of cysteamine
CN110772376A (zh) * 2019-11-20 2020-02-11 韩熠 一种用于婴幼儿及儿童的医用眼贴及其制备方法
AU2021206966A1 (en) * 2020-01-14 2022-08-04 Mochida Pharmaceutical Co., Ltd. Combination and method for treating subject using alginic acid salt
CN115066232B (zh) 2020-02-06 2024-12-10 视尔普斯眼科公司 用于治疗眼病的组合物和方法
EP4129353A4 (en) * 2020-03-25 2024-05-29 Fukuoka University Agent to be used in intraocular membrane detachment surgery
CA3171563A1 (en) * 2020-03-25 2021-09-30 Charles D. Blizzard Ocular implant containing a tyrosine kinase inhibitor
EP4142664A4 (en) 2020-04-27 2024-05-29 Ocular Therapeutix, Inc. METHODS FOR TREATING ALLERGIC CONJUNCTIVITIS
EP4149400B1 (en) * 2020-05-15 2026-04-22 Georgia Tech Research Corporation Methods and compositions for reducing intraocular pressure
EP3973952B1 (en) 2020-09-24 2024-02-14 Ocular Therapeutix, Inc. Sustained release biodegradable intracanalicular inserts comprising a hydrogel and cyclosporine
EP4216929A1 (en) 2020-09-24 2023-08-02 Ocular Therapeutix, Inc. Sustained release biodegradable intracanalicular inserts comprising a hydrogel and an active agent
US12343454B2 (en) 2020-11-12 2025-07-01 Pramand LLC Hydrogels formed in situ and composition design for intrauterine use
US20220142653A1 (en) 2020-11-12 2022-05-12 Pramand LLC Transcervical access systems for intrauterine fluid exchange, such as placement of hydrogels formed in situ
US12605311B2 (en) 2021-02-05 2026-04-21 Kao Corporation Hydrogel structure
CN113230019A (zh) * 2021-04-16 2021-08-10 南京佑羲医药科技有限公司 一种用于眼球玻璃体内植入的长效缓释给药装置
CN113367883A (zh) * 2021-06-08 2021-09-10 复旦大学附属眼耳鼻喉科医院 一种原位成胶个体化配适的角膜绷带镜
US12582767B2 (en) 2021-12-30 2026-03-24 Taiyo Weber Compressible, minimally invasive implants and related systems and methods
IL314115A (en) * 2022-02-01 2024-09-01 Ocular Therapeutix Inc Controlled release implant for biological agents and corresponding treatment methods
US12251466B2 (en) * 2022-04-20 2025-03-18 Pramand LLC Single solution hydrogels with covalent bonding formed in situ, composition design and medical procedures using the hydrogels
CN115671036A (zh) * 2022-11-15 2023-02-03 上海交通大学医学院附属第九人民医院 用于治疗眼底和眼内疾病的凝胶药物
JP2026520094A (ja) 2023-04-11 2026-06-22 オキュラ セラピューティクス，インコーポレイテッド アキシチニブ多形ｉｖを含む眼科インプラント
CN116687840B (zh) * 2023-08-03 2023-10-20 四川省医学科学院·四川省人民医院 一种用于治疗眼部病状的凝胶制剂及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010533225A (ja) 2007-07-09 2010-10-21 インセプト エルエルシー ヒドロゲルポリマー組成物及び方法
US20130071462A1 (en) 2011-09-16 2013-03-21 Peter Jarrett Drug Delivery Systems and Applications
WO2013086015A1 (en) 2011-12-05 2013-06-13 Incept, Llc Medical organogel processes and compositions
WO2014039012A1 (en) 2012-09-06 2014-03-13 Nanyang Technological University Hyaluronic acid-based drug delivery systems

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640741A (en) 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
US3865108A (en) 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US4002173A (en) 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
DE2437629C3 (de) 1974-08-05 1978-09-21 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von unlöslichen in Wasser nur wenig quellbaren Polymerisaten von N-Vinyllactamen
US4014335A (en) 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
US4207893A (en) 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
US5160745A (en) 1986-05-16 1992-11-03 The University Of Kentucky Research Foundation Biodegradable microspheres as a carrier for macromolecules
US4741872A (en) 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
IL82834A (en) 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5304595A (en) 1988-11-21 1994-04-19 Collagen Corporation Collagen-polymer conjugates
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
IL90193A (en) 1989-05-04 1993-02-21 Biomedical Polymers Int Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
ATE203885T1 (de) * 1994-09-08 2001-08-15 Stryker Technologies Corp Bandscheibenkern aus hydrogel
US6371975B2 (en) 1998-11-06 2002-04-16 Neomend, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
IL135800A0 (en) 1997-10-27 2001-05-20 Univ California Methods and pharmaceutical compositions for the closure of retinal breaks
US6958212B1 (en) 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
CA2438193A1 (en) 2001-02-26 2002-09-06 Duke University Novel dendritic polymers and their biomedical uses
US6913765B2 (en) * 2001-03-21 2005-07-05 Scimed Life Systems, Inc. Controlling resorption of bioresorbable medical implant material
US20040131582A1 (en) 2002-02-26 2004-07-08 Grinstaff Mark W. Novel dendritic polymers and their biomedical uses
JP5628467B2 (ja) * 2003-06-26 2014-11-19 シヴィダ・ユーエス・インコーポレイテッドＰｓｉｖｉｄａ Ｕｓ， Ｉｎｃ． 生体分解性徐放性ドラッグデリバリーシステム
US7129210B2 (en) 2003-07-23 2006-10-31 Covalent Medical, Inc. Tissue adhesive sealant
WO2006031358A2 (en) 2004-08-13 2006-03-23 Hyperbranch Medical Technology, Inc. Dendritic polymers, crosslinked gels, and their uses as ophthalmic sealants and lenses
WO2006031388A2 (en) 2004-08-20 2006-03-23 Hyperbranch Medical Technology, Inc. Dentritic polymers, crosslinked gels, and their uses in orthopedic applications
EP1814519A1 (en) * 2004-11-16 2007-08-08 Université de Liège Active substance delivery system comprising a hydrogel atrix and microcarriers
WO2007001926A2 (en) 2005-06-24 2007-01-04 Hyperbranch Medical Technology, Inc. Low-swelling hydrogel sealants for wound repair
WO2007005249A2 (en) 2005-06-29 2007-01-11 Hyperbranch Medical Technology, Inc. Nanoparticles and dendritic-polymer-based hydrogels comprising them
EP3960215B1 (en) 2009-12-15 2024-10-16 Incept, LLC Implants and biodegradable fiducial markers
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
HK1205461A1 (zh) * 2012-02-22 2015-12-18 Trustees Of Tufts College 用於眼部传输治疗剂的组合物和方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010533225A (ja) 2007-07-09 2010-10-21 インセプト エルエルシー ヒドロゲルポリマー組成物及び方法
US20130071462A1 (en) 2011-09-16 2013-03-21 Peter Jarrett Drug Delivery Systems and Applications
WO2013086015A1 (en) 2011-12-05 2013-06-13 Incept, Llc Medical organogel processes and compositions
WO2014039012A1 (en) 2012-09-06 2014-03-13 Nanyang Technological University Hyaluronic acid-based drug delivery systems

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ｊｏｕｒｎａｌ ｏｆ Ｃｏｎｔｒｏｌｌｅｄ Ｒｅｌｅａｓｅ， ２００３， Ｖｏｌ．９１， ｐ．２９９－３１３

Also Published As

Publication number Publication date
CN107205922A (zh) 2017-09-26
AU2015360469A1 (en) 2017-06-22
JP2017537130A (ja) 2017-12-14
EP3229779B1 (en) 2021-02-03
JP2021046429A (ja) 2021-03-25
CN120501693A (zh) 2025-08-19
CA2969716A1 (en) 2016-06-16
CA2969716C (en) 2023-12-19
KR20170117384A (ko) 2017-10-23
US20260060921A1 (en) 2026-03-05
AU2015360469B2 (en) 2021-03-25
EP3858329A1 (en) 2021-08-04
EP3229779A1 (en) 2017-10-18
WO2016094646A1 (en) 2016-06-16
US20160166504A1 (en) 2016-06-16

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