JP7092502B2 - ハイドロゲル薬物送達インプラント - Google Patents

ハイドロゲル薬物送達インプラント Download PDF

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Publication number
JP7092502B2
JP7092502B2 JP2017531184A JP2017531184A JP7092502B2 JP 7092502 B2 JP7092502 B2 JP 7092502B2 JP 2017531184 A JP2017531184 A JP 2017531184A JP 2017531184 A JP2017531184 A JP 2017531184A JP 7092502 B2 JP7092502 B2 JP 7092502B2
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hydrogel
particles
therapeutic agent
precursor
functional group
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JP2017537130A5 (enExample
JP2017537130A (ja
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ピーター・ジャレット
ラミ・エル－ハイエク
アマルプリート・エス・ソーニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2017531184A 2014-12-10 2015-12-10 ハイドロゲル薬物送達インプラント Active JP7092502B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462089994P 2014-12-10 2014-12-10
US62/089,994 2014-12-10
PCT/US2015/064975 WO2016094646A1 (en) 2014-12-10 2015-12-10 Hydrogel drug delivery implants

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020201207A Division JP2021046429A (ja) 2014-12-10 2020-12-03 ハイドロゲル薬物送達インプラント

Publications (3)

Publication Number Publication Date
JP2017537130A JP2017537130A (ja) 2017-12-14
JP2017537130A5 JP2017537130A5 (enExample) 2019-01-24
JP7092502B2 true JP7092502B2 (ja) 2022-06-28

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Family Applications (2)

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JP2017531184A Active JP7092502B2 (ja) 2014-12-10 2015-12-10 ハイドロゲル薬物送達インプラント
JP2020201207A Pending JP2021046429A (ja) 2014-12-10 2020-12-03 ハイドロゲル薬物送達インプラント

Family Applications After (1)

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JP2020201207A Pending JP2021046429A (ja) 2014-12-10 2020-12-03 ハイドロゲル薬物送達インプラント

Country Status (8)

Country Link
US (1) US20160166504A1 (enExample)
EP (2) EP3858329A1 (enExample)
JP (2) JP7092502B2 (enExample)
KR (1) KR20170117384A (enExample)
CN (2) CN120501693A (enExample)
AU (1) AU2015360469B2 (enExample)
CA (1) CA2969716C (enExample)
WO (1) WO2016094646A1 (enExample)

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CN107921237A (zh) 2015-04-27 2018-04-17 反射医学公司 交感神经心肺神经调节系统和方法
EP4279064A3 (en) * 2015-05-12 2024-02-28 Incept, LLC Drug delivery from hydrogels
US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
CN108367079B (zh) 2015-11-12 2022-11-22 灰色视觉公司 用于治疗的聚集性微粒
WO2017091749A1 (en) 2015-11-25 2017-06-01 Incept, Llc Shape changing drug delivery devices and methods
WO2017139487A1 (en) 2016-02-09 2017-08-17 Northwind Medical, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
WO2017165449A1 (en) * 2016-03-22 2017-09-28 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Thermoresponsive hydrogel containing polymer microparticles for noninvasive ocular biologic delivery
CN110035754A (zh) 2016-06-29 2019-07-19 图拉维治疗股份有限公司 通过自主神经系统的局部神经调节治疗败血症及相关炎性病况
EP3487586A4 (en) * 2016-07-20 2020-03-04 Emory University FORMULAS FOR THE SUPRACHOROIDAL SPACE OF AN EYE AND METHOD
JP7430529B2 (ja) * 2016-09-23 2024-02-13 インセプト・リミテッド・ライアビリティ・カンパニー 前房内薬物送達デポ
EP3621654A4 (en) 2017-05-10 2021-02-17 Graybug Vision, Inc. PROLONGED-RELEASE MICROPARTICLES AND SUSPENSIONS OF THESE INTENDED FOR MEDICAL THERAPY
WO2019043699A1 (en) * 2017-08-30 2019-03-07 Hadasit Medical Research Services And Development Ltd. DEVICES, KITS AND METHODS FOR REDUCING AND / OR PREVENTING INTRA-ABDOMINAL ADHESIONS
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CN112752568A (zh) * 2018-08-15 2021-05-04 微思有限公司 具有用于流动路径修饰的可生物降解材料的持续释出部件及相应的药物输送装置
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Also Published As

Publication number Publication date
AU2015360469A1 (en) 2017-06-22
CN107205922A (zh) 2017-09-26
CN120501693A (zh) 2025-08-19
KR20170117384A (ko) 2017-10-23
EP3858329A1 (en) 2021-08-04
US20160166504A1 (en) 2016-06-16
AU2015360469B2 (en) 2021-03-25
EP3229779A1 (en) 2017-10-18
CA2969716A1 (en) 2016-06-16
CA2969716C (en) 2023-12-19
WO2016094646A1 (en) 2016-06-16
JP2017537130A (ja) 2017-12-14
EP3229779B1 (en) 2021-02-03
JP2021046429A (ja) 2021-03-25

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