CA2969704C - Cs1 targeted chimeric antigen receptor-modified t cells - Google Patents

Cs1 targeted chimeric antigen receptor-modified t cells Download PDF

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CA2969704C
CA2969704C CA2969704A CA2969704A CA2969704C CA 2969704 C CA2969704 C CA 2969704C CA 2969704 A CA2969704 A CA 2969704A CA 2969704 A CA2969704 A CA 2969704A CA 2969704 C CA2969704 C CA 2969704C
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cells
amino acid
seq
sequence
car
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CA2969704A1 (en
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Stephen J. Forman
Xiuli Wang
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City of Hope
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City of Hope
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    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70521CD28, CD152
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    • A61K40/00Cellular immunotherapy
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    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31Chimeric antigen receptors [CAR]
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C12N5/0638Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • C07K2319/00Fusion polypeptide
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CA2969704A 2014-12-05 2015-12-07 Cs1 targeted chimeric antigen receptor-modified t cells Active CA2969704C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462088423P 2014-12-05 2014-12-05
US62/088,423 2014-12-05
PCT/US2015/064303 WO2016090369A1 (en) 2014-12-05 2015-12-07 Cs1 targeted chimeric antigen receptor-modified t cells

Publications (2)

Publication Number Publication Date
CA2969704A1 CA2969704A1 (en) 2016-06-09
CA2969704C true CA2969704C (en) 2023-05-02

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CA2969704A Active CA2969704C (en) 2014-12-05 2015-12-07 Cs1 targeted chimeric antigen receptor-modified t cells

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US (2) US10821161B2 (enExample)
EP (2) EP4219530A1 (enExample)
JP (2) JP7098325B2 (enExample)
KR (1) KR102558502B1 (enExample)
CN (2) CN107429253B (enExample)
AU (2) AU2015357485B2 (enExample)
BR (1) BR112017011893A2 (enExample)
CA (1) CA2969704C (enExample)
IL (3) IL290459B2 (enExample)
MX (2) MX384964B (enExample)
RU (1) RU2727451C2 (enExample)
WO (1) WO2016090369A1 (enExample)

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