CA2948043A1 - Synthetic thread based lateral flow immunoassay - Google Patents

Synthetic thread based lateral flow immunoassay Download PDF

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Publication number
CA2948043A1
CA2948043A1 CA2948043A CA2948043A CA2948043A1 CA 2948043 A1 CA2948043 A1 CA 2948043A1 CA 2948043 A CA2948043 A CA 2948043A CA 2948043 A CA2948043 A CA 2948043A CA 2948043 A1 CA2948043 A1 CA 2948043A1
Authority
CA
Canada
Prior art keywords
zone
sample
analyte
detection
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2948043A
Other languages
English (en)
French (fr)
Inventor
William Samuel Hunter
Christopher James Hurren
Sacha Marie Dopheide
Samantha Irene Couper
Mary Louise Garcia
Joy Ji Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lumos Diagnostics IP Pty Ltd
Original Assignee
NPLEX Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2014901679A external-priority patent/AU2014901679A0/en
Application filed by NPLEX Pty Ltd filed Critical NPLEX Pty Ltd
Publication of CA2948043A1 publication Critical patent/CA2948043A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CA2948043A 2014-05-07 2015-05-07 Synthetic thread based lateral flow immunoassay Abandoned CA2948043A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2014901679A AU2014901679A0 (en) 2014-05-07 Synthetic thread based lateral flow immunoassay
AU2014901679 2014-05-07
PCT/AU2015/050220 WO2015168740A1 (en) 2014-05-07 2015-05-07 Synthetic thread based lateral flow immunoassay

Publications (1)

Publication Number Publication Date
CA2948043A1 true CA2948043A1 (en) 2015-11-12

Family

ID=54391865

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2948043A Abandoned CA2948043A1 (en) 2014-05-07 2015-05-07 Synthetic thread based lateral flow immunoassay

Country Status (8)

Country Link
US (1) US10379119B2 (enExample)
EP (1) EP3140652A4 (enExample)
JP (1) JP2017515130A (enExample)
KR (1) KR20170007773A (enExample)
CN (1) CN106461648B (enExample)
AU (1) AU2015255636A1 (enExample)
CA (1) CA2948043A1 (enExample)
WO (1) WO2015168740A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3053110A1 (en) * 2017-02-10 2018-08-16 Quidel Corporation Lateral flow assay with substrate having channels for controlled fluid flow
CN107505459B (zh) * 2017-07-03 2019-12-24 广州瑞博奥生物科技有限公司 定量检测人h-fabp的时间分辨荧光免疫层析试纸条、试剂盒及其制备方法
JP7451403B2 (ja) * 2017-12-05 2024-03-18 ベクトン・ディキンソン・アンド・カンパニー 高濃度の分析物を検出するための側方流動アッセイ及び方法
GB201721796D0 (en) * 2017-12-22 2018-02-07 Univ Southampton Lateral flow diagnostic device
JP2019113425A (ja) * 2017-12-25 2019-07-11 Ｂｌｕｅ Ｉｎｄｕｓｔｒｉｅｓ株式会社 イムノクロマトアッセイ用検査カートリッジ及び検査装置
CN108918479A (zh) * 2018-04-04 2018-11-30 苏州遵道生物科技有限公司 定量检测白细胞介素-6的时间分辨荧光免疫层析试纸条及其制备方法
EP3807618A4 (en) * 2018-06-18 2022-01-19 Becton, Dickinson and Company Systems, devices, and methods for amplifying signals of a lateral flow assay
CN109799355A (zh) * 2019-02-06 2019-05-24 吉林双正生物工程有限公司 甲功五项的荧光微球联合检测装置及其制备方法
US20210055284A1 (en) * 2019-08-20 2021-02-25 Zding Tech LLC Microchip immunoassay device having precise incubation time control and signal scaling and related methods
CN111024946A (zh) * 2019-11-19 2020-04-17 江苏美克医学技术有限公司 阴道毛滴虫荧光免疫层析测定试剂盒及其制备方法
CN111426831B (zh) * 2020-03-24 2023-09-15 山东康华生物医疗科技股份有限公司 一种联合检测2019新型冠状病毒IgM和IgG抗体的试剂盒及其制备方法
CN111505267B (zh) * 2020-04-28 2023-05-12 上海泰辉生物科技有限公司 一种时间分辨免疫分析检测系统与检测方法
KR102601981B1 (ko) 2021-01-04 2023-11-13 인하대학교 산학협력단 변형된 측면 유동 면역진단 스트립
US12493034B2 (en) * 2021-01-08 2025-12-09 George Mason University Reagent buffer
CN120958059A (zh) * 2023-02-03 2025-11-14 丹尼米尔知识产权有限责任公司 可生物降解的试剂盒

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4058732A (en) 1975-06-30 1977-11-15 Analytical Radiation Corporation Method and apparatus for improved analytical fluorescent spectroscopy
US4283382A (en) 1977-12-28 1981-08-11 Eastman Kodak Company Fluorescent labels comprising rare earth chelates
US4459360A (en) * 1981-10-05 1984-07-10 Mast Medical Industries, Ltd. Multiple-component binding assay system and method of making and using it
US4673657A (en) * 1983-08-26 1987-06-16 The Regents Of The University Of California Multiple assay card and system
US4708931A (en) * 1984-06-01 1987-11-24 Regents Of University Of California Laminated rod having alternating detection and spacer layers for binding assays
US4719182A (en) 1985-03-18 1988-01-12 Eastman Kodak Company Fluorescent labels and labeled species and their use in analytical elements and determinations
US5122452A (en) * 1987-05-20 1992-06-16 Carleton University Enzyme immunoassay with a macroporous hydrophobic synthetic polymer cloth containing an immobilized antibody or antigen
US5252496A (en) * 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
US5451504A (en) 1991-07-29 1995-09-19 Serex, Inc. Method and device for detecting the presence of analyte in a sample
WO1997038312A1 (en) * 1996-04-10 1997-10-16 Scripps Laboratories, Inc. Diagnostic test device utilizing filaments containing reagents
WO1998008093A1 (en) * 1996-08-16 1998-02-26 Oy Medix Biochemica Ab Coated flexible thread-like solid carrier for immunoassays
US6833111B2 (en) 2001-04-13 2004-12-21 Varian, Inc. Multiple analyte assaying device with a multiple sample introduction system
CN104076143B (zh) * 2003-05-02 2017-06-13 安克塞斯生物公司 层析分析系统
JP2007530946A (ja) 2004-03-23 2007-11-01 クイデル コーポレイション ハイブリッド相ラテラルフロー・アッセイ
CN102016594B (zh) * 2008-03-27 2014-04-23 哈佛学院院长等 用作低成本多重分析诊断平台的棉线
CN101539580A (zh) * 2009-03-18 2009-09-23 侯巍 蛋白质荧光检测卡及检测方法
EP2591152A1 (en) * 2010-07-05 2013-05-15 Achira Labs Pvt. Ltd. Methods of making a diagnostic composition and compositions therefrom
JP2012032263A (ja) * 2010-07-30 2012-02-16 Kinki Univ 蛍光微粒子含有免疫測定用試薬
JP5342584B2 (ja) * 2011-03-09 2013-11-13 古河電気工業株式会社 ラテラルフロー用テストストリップ
CN104813166B (zh) * 2012-09-28 2016-05-04 积水医疗株式会社 用于测量非稀释类型免疫层析法试剂中的样品的添加剂
CN103105492A (zh) * 2013-01-17 2013-05-15 重庆市科学技术研究院 一种荧光免疫层析流感病毒检测试纸

Also Published As

Publication number Publication date
US10379119B2 (en) 2019-08-13
AU2015255636A1 (en) 2016-11-24
EP3140652A4 (en) 2017-11-29
CN106461648A (zh) 2017-02-22
KR20170007773A (ko) 2017-01-20
JP2017515130A (ja) 2017-06-08
EP3140652A1 (en) 2017-03-15
WO2015168740A1 (en) 2015-11-12
CN106461648B (zh) 2019-04-26
US20170074874A1 (en) 2017-03-16

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20200427

FZDE Discontinued

Effective date: 20220928

FZDE Discontinued

Effective date: 20220928