CA2938703C - Substituted thiazole or oxazole p2x7 receptor antagonists - Google Patents

Substituted thiazole or oxazole p2x7 receptor antagonists Download PDF

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CA2938703C
CA2938703C CA2938703A CA2938703A CA2938703C CA 2938703 C CA2938703 C CA 2938703C CA 2938703 A CA2938703 A CA 2938703A CA 2938703 A CA2938703 A CA 2938703A CA 2938703 C CA2938703 C CA 2938703C
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compound
formula
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CA2938703A1 (en
Inventor
Paolo Pevarello
Stefan Lohmer
Chiara Liberati
Pierfausto Seneci
Cristina PESENTI
Adolfo Prandi
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Breye Therapeutics ApS
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AXXAM SpA
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    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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EP3290417A1 (en) 2016-08-31 2018-03-07 AXXAM S.p.A. 2-chloro-n-[2-(1,3-thiazol-5-yl)ethyl]-5-(5-fluoropyrimidin-2-yl)-benzamides and their use as p2x7 receptor antagonists
EP3290416A1 (en) * 2016-08-31 2018-03-07 AXXAM S.p.A. Substituted n-[2-(4-phenoxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamide and n-[2-(4-benzyloxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamide derivatives and their use as p2x7 receptor antagonist
CN106562947A (zh) * 2016-11-03 2017-04-19 南昌大学 亮蓝g在制备人类免疫缺陷病毒糖蛋白120诱导神经病理痛药物中的应用
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