CA2917095C - Devices and methods for the ultrasound treatment of ischemic stroke - Google Patents

Devices and methods for the ultrasound treatment of ischemic stroke Download PDF

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Publication number
CA2917095C
CA2917095C CA2917095A CA2917095A CA2917095C CA 2917095 C CA2917095 C CA 2917095C CA 2917095 A CA2917095 A CA 2917095A CA 2917095 A CA2917095 A CA 2917095A CA 2917095 C CA2917095 C CA 2917095C
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CA
Canada
Prior art keywords
ultrasound
occlusion
site
acoustic pressure
mid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2917095A
Other languages
English (en)
French (fr)
Other versions
CA2917095A1 (en
Inventor
Jeffry Earl Powers
Ralf Seip
William Tao Shi
Francois Tranquart
Yannick BOHREN
Emmanuel Jean-Marie GAUD
Ebeline BIHEL
Feng Yan
Marcel Arditi
Jean-Marc Paul Robert HYVELIN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Suisse SA
Koninklijke Philips NV
Original Assignee
Bracco Suisse SA
Koninklijke Philips NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Suisse SA, Koninklijke Philips NV filed Critical Bracco Suisse SA
Publication of CA2917095A1 publication Critical patent/CA2917095A1/en
Application granted granted Critical
Publication of CA2917095C publication Critical patent/CA2917095C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Clinical applications
    • A61B8/0833—Clinical applications involving detecting or locating foreign bodies or organic structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005—Effects, e.g. on tissue
    • A61B2017/22007—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005—Effects, e.g. on tissue
    • A61B2017/22007—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • A61B2017/22008—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing used or promoted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/483—Diagnostic techniques involving the acquisition of a 3D volume of data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5238—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
    • A61B8/5246—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from the same or different imaging techniques, e.g. color Doppler and B-mode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0004—Applications of ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0039—Ultrasound therapy using microbubbles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0052—Ultrasound therapy using the same transducer for therapy and imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0078—Ultrasound therapy with multiple treatment transducers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0086—Beam steering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Mechanical Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgical Instruments (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Percussion Or Vibration Massage (AREA)
CA2917095A 2013-07-03 2014-07-02 Devices and methods for the ultrasound treatment of ischemic stroke Active CA2917095C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361842402P 2013-07-03 2013-07-03
US201361842404P 2013-07-03 2013-07-03
US61/842,402 2013-07-03
US61/842,404 2013-07-03
EP13182062 2013-08-28
EP13182062.3 2013-08-28
PCT/EP2014/064052 WO2015000953A1 (en) 2013-07-03 2014-07-02 Devices and methods for the ultrasound treatment of ischemic stroke

Publications (2)

Publication Number Publication Date
CA2917095A1 CA2917095A1 (en) 2015-01-08
CA2917095C true CA2917095C (en) 2021-11-02

Family

ID=49036479

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2917095A Active CA2917095C (en) 2013-07-03 2014-07-02 Devices and methods for the ultrasound treatment of ischemic stroke

Country Status (7)

Country Link
US (1) US10926112B2 (enExample)
EP (1) EP3016713B1 (enExample)
JP (1) JP6568057B2 (enExample)
CN (1) CN105407968B (enExample)
BR (1) BR112015032732B1 (enExample)
CA (1) CA2917095C (enExample)
WO (1) WO2015000953A1 (enExample)

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WO2015003154A1 (en) 2013-07-03 2015-01-08 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
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WO2015027164A1 (en) 2013-08-22 2015-02-26 The Regents Of The University Of Michigan Histotripsy using very short ultrasound pulses
US11141179B2 (en) 2014-12-11 2021-10-12 Koninklijke Philips N.V. Setting of sonothromobolysis ultrasound output power
WO2016210133A1 (en) * 2015-06-24 2016-12-29 The Regents Of The Universtiy Of Michigan Histotripsy therapy systems and methods for the treatment of brain tissue
US11284910B2 (en) 2015-12-09 2022-03-29 Koninklijke Philips N.V. Interleaved beam pattern for sonothhrombolysis and other vascular acoustic resonator mediated therapies
US10589129B2 (en) * 2016-09-14 2020-03-17 Insightec, Ltd. Therapeutic ultrasound with reduced interference from microbubbles
US11259781B2 (en) 2016-12-16 2022-03-01 Koninklijke Philips N.V. Adaptive pulsing for sonothrombolysis treatment
US11369810B2 (en) * 2016-12-19 2022-06-28 Michalakis Averkiou Method and apparatus for ultrasonic mediation of drug delivery using microbubbles
WO2020039082A1 (en) * 2018-08-24 2020-02-27 Neuravi Limited Apparatus for managing acute ischemic events
CN113164181A (zh) 2018-08-24 2021-07-23 尼尔拉维有限公司 用于管理急性缺血性事件的设备
CA3120586A1 (en) 2018-11-28 2020-06-04 Histosonics, Inc. Histotripsy systems and methods
KR20200078365A (ko) * 2018-12-19 2020-07-01 뉴라비 리미티드 급성 허혈성 사건을 관리하기 위한 방법 및 장치
JP2023513012A (ja) 2020-01-28 2023-03-30 ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン ヒストトリプシー免疫感作のためのシステムおよび方法
BR112022025722A2 (pt) 2020-06-18 2023-03-07 Histosonics Inc Sistemas e métodos de acoplamento acústico e paciente de histotripsia
JP2023538245A (ja) * 2020-08-11 2023-09-07 アミール・イー・ハサン 術者非依存ヒストトリプシデバイス
CN116782843A (zh) 2020-08-27 2023-09-19 密歇根大学董事会 用于组织摧毁术的具有发射-接收能力的超声换能器
ES2972017T3 (es) * 2020-09-21 2024-06-10 Servicio Andaluz De Salud Dispositivo para la limpieza preventiva no invasiva de sistemas de derivación de líquido cefalorraquídeo
EP4351447A4 (en) 2021-06-07 2025-07-16 Univ Michigan Regents ALL-IN-ONE ULTRASOUND SYSTEMS AND METHODS INCLUDING HISTOTRIPSY
US12582848B2 (en) 2021-06-07 2026-03-24 The Regents Of The University Of Michigan Minimally invasive histotripsy systems and methods
CN113974765B (zh) * 2021-10-22 2022-09-06 北京荷清和创医疗科技有限公司 介入式除栓装置及促溶栓模块
CN115105123A (zh) * 2022-05-31 2022-09-27 深圳迈瑞生物医疗电子股份有限公司 一种超声成像系统和方法
WO2024092272A1 (en) 2022-10-28 2024-05-02 Histosonics, Inc. Histotripsy systems and methods
USD1037522S1 (en) 2022-11-30 2024-07-30 Eaton Intelligent Power Limited Floodlight
KR20260003742A (ko) 2023-04-20 2026-01-07 히스토소닉스, 인크. 치료 계획 및 요법을 위한 사용자 인터페이스들 및 작업 흐름들을 포함하는 히스토트립시 시스템들 및 연관된 방법들

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Also Published As

Publication number Publication date
BR112015032732B1 (pt) 2022-05-17
JP6568057B2 (ja) 2019-08-28
EP3016713B1 (en) 2023-03-01
CN105407968A (zh) 2016-03-16
JP2016526976A (ja) 2016-09-08
CN105407968B (zh) 2019-09-03
BR112015032732A2 (pt) 2017-07-25
CA2917095A1 (en) 2015-01-08
US10926112B2 (en) 2021-02-23
US20160279449A1 (en) 2016-09-29
WO2015000953A1 (en) 2015-01-08
EP3016713A1 (en) 2016-05-11

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