CA2910320A1 - Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease - Google Patents
Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus diseaseInfo
- Publication number
- CA2910320A1 CA2910320A1 CA2910320A CA2910320A CA2910320A1 CA 2910320 A1 CA2910320 A1 CA 2910320A1 CA 2910320 A CA2910320 A CA 2910320A CA 2910320 A CA2910320 A CA 2910320A CA 2910320 A1 CA2910320 A1 CA 2910320A1
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- Prior art keywords
- seq
- polypeptide
- cdr2
- cdr3
- cdr1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261638797P | 2012-04-26 | 2012-04-26 | |
| US61/638,797 | 2012-04-26 | ||
| PCT/US2013/031927 WO2013162751A1 (en) | 2012-04-26 | 2013-03-15 | Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2910320A1 true CA2910320A1 (en) | 2013-10-31 |
Family
ID=49483735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2910320A Abandoned CA2910320A1 (en) | 2012-04-26 | 2013-03-15 | Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9701738B2 (enExample) |
| EP (1) | EP2841101B1 (enExample) |
| JP (2) | JP6251730B2 (enExample) |
| CN (1) | CN104703622B (enExample) |
| AU (1) | AU2013252888B2 (enExample) |
| BR (1) | BR112014026808A2 (enExample) |
| CA (1) | CA2910320A1 (enExample) |
| HK (1) | HK1207321A1 (enExample) |
| NZ (1) | NZ702282A (enExample) |
| WO (1) | WO2013162751A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9181329B2 (en) * | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
| WO2013162746A1 (en) * | 2012-04-26 | 2013-10-31 | University Of Chicago | Staphylococcal coagulase antigens and methods of their use |
| WO2015112895A2 (en) * | 2014-01-24 | 2015-07-30 | Church William R | Antibody specific to staphylococcus aureus, therapeutic method and detection method using same |
| JP7117244B2 (ja) * | 2016-02-12 | 2022-08-12 | ザ・ユニバーシティ・オブ・シカゴ | 黄色ブドウ球菌疾患の間にコアグラーゼ活性を中和する抗体に関連した組成物および方法 |
| EP3475304B1 (en) * | 2016-06-28 | 2022-03-23 | Xencor, Inc. | Heterodimeric antibodies that bind somatostatin receptor 2 |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| JP6908111B2 (ja) * | 2017-06-30 | 2021-07-21 | 日本電気株式会社 | 予測装置、予測方法、予測プログラム、及び、遺伝子推定装置 |
| JP7460531B2 (ja) | 2017-12-05 | 2024-04-02 | バイオピーエルエックス,インコーポレイティド | 微生物感染を防ぐための方法および組成物 |
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| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4196265A (en) | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4338298A (en) | 1980-04-04 | 1982-07-06 | Endowment And Research Foundation At Montana State University | Vaccine for passive immunization against enteric colibacillosis and method of use |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
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| US4938948A (en) | 1985-10-07 | 1990-07-03 | Cetus Corporation | Method for imaging breast tumors using labeled monoclonal anti-human breast cancer antibodies |
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-
2013
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- 2013-03-15 WO PCT/US2013/031927 patent/WO2013162751A1/en not_active Ceased
- 2013-03-15 BR BR112014026808A patent/BR112014026808A2/pt not_active Application Discontinuation
- 2013-03-15 NZ NZ702282A patent/NZ702282A/en not_active IP Right Cessation
- 2013-03-15 US US14/397,049 patent/US9701738B2/en active Active
- 2013-03-15 AU AU2013252888A patent/AU2013252888B2/en not_active Ceased
- 2013-03-15 JP JP2015508964A patent/JP6251730B2/ja active Active
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- 2013-03-15 HK HK15108152.0A patent/HK1207321A1/xx unknown
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2017
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- 2017-11-27 JP JP2017226624A patent/JP2018058871A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015515492A (ja) | 2015-05-28 |
| AU2013252888A1 (en) | 2014-12-11 |
| JP6251730B2 (ja) | 2017-12-20 |
| JP2018058871A (ja) | 2018-04-12 |
| US20170306004A1 (en) | 2017-10-26 |
| NZ702282A (en) | 2016-07-29 |
| CN104703622B (zh) | 2017-05-24 |
| EP2841101A1 (en) | 2015-03-04 |
| EP2841101A4 (en) | 2016-02-24 |
| US9701738B2 (en) | 2017-07-11 |
| CN104703622A (zh) | 2015-06-10 |
| BR112014026808A2 (pt) | 2018-05-15 |
| WO2013162751A1 (en) | 2013-10-31 |
| US20150368322A1 (en) | 2015-12-24 |
| EP2841101B1 (en) | 2019-08-07 |
| HK1207321A1 (en) | 2016-01-29 |
| AU2013252888B2 (en) | 2018-06-14 |
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