BR112014026808A2 - composições e métodos relacionados a anticorpos que neutralizam atividade de coagulase durante doença por staphylococcus aureus - Google Patents

composições e métodos relacionados a anticorpos que neutralizam atividade de coagulase durante doença por staphylococcus aureus

Info

Publication number
BR112014026808A2
BR112014026808A2 BR112014026808A BR112014026808A BR112014026808A2 BR 112014026808 A2 BR112014026808 A2 BR 112014026808A2 BR 112014026808 A BR112014026808 A BR 112014026808A BR 112014026808 A BR112014026808 A BR 112014026808A BR 112014026808 A2 BR112014026808 A2 BR 112014026808A2
Authority
BR
Brazil
Prior art keywords
methods
compositions
antibody
coagulase
staphylococcus aureus
Prior art date
Application number
BR112014026808A
Other languages
English (en)
Portuguese (pt)
Inventor
Emolo Carla
M Missiakas Dominique
Mcadow Molly
Schneewind Olaf
Original Assignee
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Chicago filed Critical Univ Chicago
Publication of BR112014026808A2 publication Critical patent/BR112014026808A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR112014026808A 2012-04-26 2013-03-15 composições e métodos relacionados a anticorpos que neutralizam atividade de coagulase durante doença por staphylococcus aureus BR112014026808A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261638797P 2012-04-26 2012-04-26
PCT/US2013/031927 WO2013162751A1 (en) 2012-04-26 2013-03-15 Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease

Publications (1)

Publication Number Publication Date
BR112014026808A2 true BR112014026808A2 (pt) 2018-05-15

Family

ID=49483735

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014026808A BR112014026808A2 (pt) 2012-04-26 2013-03-15 composições e métodos relacionados a anticorpos que neutralizam atividade de coagulase durante doença por staphylococcus aureus

Country Status (10)

Country Link
US (2) US9701738B2 (enExample)
EP (1) EP2841101B1 (enExample)
JP (2) JP6251730B2 (enExample)
CN (1) CN104703622B (enExample)
AU (1) AU2013252888B2 (enExample)
BR (1) BR112014026808A2 (enExample)
CA (1) CA2910320A1 (enExample)
HK (1) HK1207321A1 (enExample)
NZ (1) NZ702282A (enExample)
WO (1) WO2013162751A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9181329B2 (en) * 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
BR112014026861A2 (pt) * 2012-04-26 2018-05-15 Univ Chicago antígenos de estafilococos coagulase e métodos de seu uso
CA2937054C (en) * 2014-01-24 2023-02-14 William R. Church Antibody specific to staphylococcus aureus, therapeutic method and detection method using same
JP7117244B2 (ja) * 2016-02-12 2022-08-12 ザ・ユニバーシティ・オブ・シカゴ 黄色ブドウ球菌疾患の間にコアグラーゼ活性を中和する抗体に関連した組成物および方法
KR20190020341A (ko) * 2016-06-28 2019-02-28 젠코어 인코포레이티드 소마토스타틴 수용체 2에 결합하는 이종이량체 항체
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
EP3648109A4 (en) * 2017-06-30 2020-06-24 Nec Corporation PREDICTION DEVICE, PREDICTION METHOD, INFORMATION MEDIUM STORED WITH PREDICTION PROGRAM, AND GENETIC INFERENCE DEVICE
AU2018379996A1 (en) 2017-12-05 2020-06-25 BioPlx, Inc. Methods and compositions to prevent microbial infection

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Also Published As

Publication number Publication date
WO2013162751A1 (en) 2013-10-31
JP2018058871A (ja) 2018-04-12
CN104703622A (zh) 2015-06-10
AU2013252888A1 (en) 2014-12-11
JP6251730B2 (ja) 2017-12-20
US20170306004A1 (en) 2017-10-26
HK1207321A1 (en) 2016-01-29
US20150368322A1 (en) 2015-12-24
NZ702282A (en) 2016-07-29
AU2013252888B2 (en) 2018-06-14
CA2910320A1 (en) 2013-10-31
EP2841101A4 (en) 2016-02-24
EP2841101A1 (en) 2015-03-04
CN104703622B (zh) 2017-05-24
JP2015515492A (ja) 2015-05-28
EP2841101B1 (en) 2019-08-07
US9701738B2 (en) 2017-07-11

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B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B07D Technical examination (opinion) related to article 229 of industrial property law

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B07E Notice of approval relating to section 229 industrial property law
B06U Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements