CA2907832A1 - Antibacterial biaromatic derivatives - Google Patents
Antibacterial biaromatic derivativesInfo
- Publication number
- CA2907832A1 CA2907832A1 CA2907832A CA2907832A CA2907832A1 CA 2907832 A1 CA2907832 A1 CA 2907832A1 CA 2907832 A CA2907832 A CA 2907832A CA 2907832 A CA2907832 A CA 2907832A CA 2907832 A1 CA2907832 A1 CA 2907832A1
- Authority
- CA
- Canada
- Prior art keywords
- oxo
- oxazolidin
- pyrido
- methoxy
- oxazin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IBPCT/IB2013/053021 | 2013-04-16 | ||
| IB2013053021 | 2013-04-16 | ||
| PCT/IB2014/060724 WO2014170821A1 (en) | 2013-04-16 | 2014-04-15 | Antibacterial biaromatic derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2907832A1 true CA2907832A1 (en) | 2014-10-23 |
Family
ID=50639826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2907832A Abandoned CA2907832A1 (en) | 2013-04-16 | 2014-04-15 | Antibacterial biaromatic derivatives |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9527867B2 (enExample) |
| EP (1) | EP2986607B1 (enExample) |
| JP (1) | JP6375365B2 (enExample) |
| KR (1) | KR20150143720A (enExample) |
| CN (1) | CN105143216B (enExample) |
| AR (1) | AR095884A1 (enExample) |
| AU (1) | AU2014255326B2 (enExample) |
| BR (1) | BR112015026261A8 (enExample) |
| CA (1) | CA2907832A1 (enExample) |
| CL (1) | CL2015003019A1 (enExample) |
| EA (1) | EA029361B1 (enExample) |
| ES (1) | ES2640482T3 (enExample) |
| HK (1) | HK1221459A1 (enExample) |
| MA (1) | MA38588B1 (enExample) |
| MX (1) | MX362338B (enExample) |
| PH (1) | PH12015502411A1 (enExample) |
| PL (1) | PL2986607T3 (enExample) |
| SA (1) | SA515361261B1 (enExample) |
| SG (1) | SG11201508479RA (enExample) |
| TW (1) | TWI631119B (enExample) |
| WO (1) | WO2014170821A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101294962B1 (ko) | 2008-10-07 | 2013-08-12 | 액테리온 파마슈티칼 리미티드 | 트리사이클 옥사졸리디논 항생제 화합물 |
| AR102256A1 (es) * | 2014-10-15 | 2017-02-15 | Actelion Pharmaceuticals Ltd | Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi |
| UY36851A (es) | 2015-08-16 | 2017-03-31 | Glaxosmithkline Ip Dev Ltd | Compuestos para uso en aplicaciones antibacterianas |
| JP2019513700A (ja) | 2016-03-16 | 2019-05-30 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 殺有害生物剤及び植物保護剤としてのｎ−（シアノベンジル）−６−（シクロプロピル−カルボニルアミノ）−４−（フェニル）−ピリジン−２−カルボキサミド誘導体及び関連する化合物 |
| AR108108A1 (es) | 2016-04-14 | 2018-07-18 | Idorsia Pharmaceuticals Ltd | Derivados biaromáticos antibacterianos con sustitución de oxetan-3-iloxi |
| GB2550437B (en) * | 2016-05-20 | 2021-06-23 | Bugworks Res Inc | Heterocyclic compounds useful as anti-bacterial agents and method for production |
| TW201833120A (zh) * | 2017-02-17 | 2018-09-16 | 瑞士商愛杜西亞製藥有限公司 | 芳基噁唑啶酮抗生素化合物 |
| EP3284739A1 (de) | 2017-07-19 | 2018-02-21 | Bayer CropScience Aktiengesellschaft | Substituierte (het)arylverbindungen als schädlingsbekämpfungsmittel |
| WO2019106693A1 (en) * | 2017-11-29 | 2019-06-06 | Bugworks Research India Pvt Ltd | Anti-bacterial heterocyclic compounds and their synthesis |
| AU2019322538B2 (en) | 2018-08-13 | 2021-09-30 | F. Hoffmann-La Roche Ag | New heterocyclic compounds as monoacylglycerol lipase inhibitors |
| PL3883936T3 (pl) | 2018-11-22 | 2023-11-20 | F. Hoffmann-La Roche Ag | Nowe związki heterocykliczne |
| MX2022002311A (es) | 2019-09-12 | 2022-03-25 | Hoffmann La Roche | Compuestos de 4,4a,5,7,8,8a-hexapirido[4,3-b][1,4]oxazin-3-ona como inhibidores de monoacilglicerol lipasa (magl). |
| CN115298176A (zh) * | 2020-03-24 | 2022-11-04 | 豪夫迈·罗氏有限公司 | 化合物以及它们在治疗细菌感染中的用途 |
| CN115785718B (zh) * | 2022-11-25 | 2023-08-22 | 四川大学 | 一种多基底表面的金属配位抗菌涂层及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0297042A1 (de) | 1987-06-23 | 1988-12-28 | Ciba-Geigy Ag | Substituierte Penem-Verbindungen |
| DE19802239A1 (de) | 1998-01-22 | 1999-07-29 | Bayer Ag | Neue mit Bicyclen substituierte Oxazolidinone |
| AU1026901A (en) | 1999-10-29 | 2001-05-08 | Syngenta Participations Ag | Novel herbicides |
| WO2003043997A1 (en) | 2001-11-15 | 2003-05-30 | Eli Lilly And Company | Peroxisome proliferator activated receptor alpha agonists |
| TW200406413A (en) | 2002-06-26 | 2004-05-01 | Glaxo Group Ltd | Compounds |
| WO2006102674A2 (en) | 2005-03-24 | 2006-09-28 | Microbia, Inc. | Diphenylheterocycle cholesterol absorption inhibitors |
| TW200734311A (en) | 2005-11-21 | 2007-09-16 | Astrazeneca Ab | New compounds |
| US7998992B2 (en) | 2007-03-30 | 2011-08-16 | Institute Of Medicinal Molecular Design, Inc. | Oxazolidinone derivative having inhibitory activity on 11β-hydroxysteroid dehydrogenase type 1 |
| CL2008001003A1 (es) * | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| BRPI0821116B8 (pt) | 2007-12-20 | 2021-05-25 | Pharma Mar Sa | composto, composição farmacêutica que o contem, uso deste e processo para a preparação do mesmo |
| ES2411930T3 (es) | 2008-02-20 | 2013-07-09 | Actelion Pharmaceuticals Ltd. | Compuestos antibióticos azatricíclicos |
| JP5404652B2 (ja) | 2008-02-22 | 2014-02-05 | アクテリオン ファーマシューティカルズ リミテッド | オキサゾリジノン誘導体 |
| EP2321307B1 (en) * | 2008-08-04 | 2012-12-19 | Actelion Pharmaceuticals Ltd. | Tricyclic alkylaminomethyloxazolidinone derivatives |
| KR101294962B1 (ko) | 2008-10-07 | 2013-08-12 | 액테리온 파마슈티칼 리미티드 | 트리사이클 옥사졸리디논 항생제 화합물 |
| CA2738775A1 (en) * | 2008-10-10 | 2010-04-15 | Actelion Pharmaceuticals Ltd | 2-benzothiophenyl-and 2-naphthyl-0xaz0lidin0nes and their azaisostere analogues as antibacterial agents |
| JP6030146B2 (ja) | 2011-11-08 | 2016-11-24 | アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | ２−オキソ−オキサゾリジン−３，５−ジイル抗生物質誘導体 |
-
2014
- 2014-04-15 EA EA201501025A patent/EA029361B1/ru not_active IP Right Cessation
- 2014-04-15 SG SG11201508479RA patent/SG11201508479RA/en unknown
- 2014-04-15 MX MX2015014576A patent/MX362338B/es active IP Right Grant
- 2014-04-15 CA CA2907832A patent/CA2907832A1/en not_active Abandoned
- 2014-04-15 CN CN201480022059.9A patent/CN105143216B/zh not_active Expired - Fee Related
- 2014-04-15 MA MA38588A patent/MA38588B1/fr unknown
- 2014-04-15 PL PL14721539T patent/PL2986607T3/pl unknown
- 2014-04-15 US US14/784,602 patent/US9527867B2/en not_active Expired - Fee Related
- 2014-04-15 EP EP14721539.6A patent/EP2986607B1/en not_active Not-in-force
- 2014-04-15 AU AU2014255326A patent/AU2014255326B2/en not_active Ceased
- 2014-04-15 WO PCT/IB2014/060724 patent/WO2014170821A1/en not_active Ceased
- 2014-04-15 HK HK16109490.8A patent/HK1221459A1/zh unknown
- 2014-04-15 ES ES14721539.6T patent/ES2640482T3/es active Active
- 2014-04-15 TW TW103113729A patent/TWI631119B/zh not_active IP Right Cessation
- 2014-04-15 KR KR1020157032552A patent/KR20150143720A/ko not_active Abandoned
- 2014-04-15 BR BR112015026261A patent/BR112015026261A8/pt not_active Application Discontinuation
- 2014-04-15 JP JP2016508263A patent/JP6375365B2/ja not_active Expired - Fee Related
- 2014-04-16 AR ARP140101625A patent/AR095884A1/es unknown
-
2015
- 2015-10-04 SA SA515361261A patent/SA515361261B1/ar unknown
- 2015-10-09 CL CL2015003019A patent/CL2015003019A1/es unknown
- 2015-10-16 PH PH12015502411A patent/PH12015502411A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20160075722A1 (en) | 2016-03-17 |
| CN105143216B (zh) | 2018-04-13 |
| EA029361B1 (ru) | 2018-03-30 |
| HK1221459A1 (zh) | 2017-06-02 |
| SA515361261B1 (ar) | 2016-06-15 |
| AR095884A1 (es) | 2015-11-18 |
| MX2015014576A (es) | 2016-03-04 |
| MA38588A1 (fr) | 2017-05-31 |
| PL2986607T3 (pl) | 2017-11-30 |
| BR112015026261A2 (pt) | 2017-07-25 |
| PH12015502411A1 (en) | 2016-02-22 |
| CL2015003019A1 (es) | 2016-09-30 |
| EA201501025A1 (ru) | 2016-08-31 |
| AU2014255326B2 (en) | 2018-09-13 |
| TWI631119B (zh) | 2018-08-01 |
| BR112015026261A8 (pt) | 2017-12-26 |
| KR20150143720A (ko) | 2015-12-23 |
| AU2014255326A1 (en) | 2015-11-26 |
| CN105143216A (zh) | 2015-12-09 |
| WO2014170821A1 (en) | 2014-10-23 |
| MX362338B (es) | 2019-01-11 |
| TW201516043A (zh) | 2015-05-01 |
| ES2640482T3 (es) | 2017-11-03 |
| EP2986607A1 (en) | 2016-02-24 |
| JP2016516805A (ja) | 2016-06-09 |
| EP2986607B1 (en) | 2017-06-14 |
| US9527867B2 (en) | 2016-12-27 |
| JP6375365B2 (ja) | 2018-08-15 |
| MA38588B1 (fr) | 2018-04-30 |
| SG11201508479RA (en) | 2015-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20190412 |
|
| FZDE | Discontinued |
Effective date: 20220808 |