SG11201508479RA - Antibacterial biaromatic derivatives - Google Patents

Antibacterial biaromatic derivatives

Info

Publication number
SG11201508479RA
SG11201508479RA SG11201508479RA SG11201508479RA SG11201508479RA SG 11201508479R A SG11201508479R A SG 11201508479RA SG 11201508479R A SG11201508479R A SG 11201508479RA SG 11201508479R A SG11201508479R A SG 11201508479RA SG 11201508479R A SG11201508479R A SG 11201508479RA
Authority
SG
Singapore
Prior art keywords
antibacterial
derivatives
biaromatic derivatives
antibacterial biaromatic
biaromatic
Prior art date
Application number
SG11201508479RA
Inventor
Sylvaine Cren
Astrid Friedli
Christian Hubschwerlen
Georg Rueedi
Cornelia Zumbrunn
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of SG11201508479RA publication Critical patent/SG11201508479RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201508479RA 2013-04-16 2014-04-15 Antibacterial biaromatic derivatives SG11201508479RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2013053021 2013-04-16
PCT/IB2014/060724 WO2014170821A1 (en) 2013-04-16 2014-04-15 Antibacterial biaromatic derivatives

Publications (1)

Publication Number Publication Date
SG11201508479RA true SG11201508479RA (en) 2015-11-27

Family

ID=50639826

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201508479RA SG11201508479RA (en) 2013-04-16 2014-04-15 Antibacterial biaromatic derivatives

Country Status (21)

Country Link
US (1) US9527867B2 (en)
EP (1) EP2986607B1 (en)
JP (1) JP6375365B2 (en)
KR (1) KR20150143720A (en)
CN (1) CN105143216B (en)
AR (1) AR095884A1 (en)
AU (1) AU2014255326B2 (en)
BR (1) BR112015026261A8 (en)
CA (1) CA2907832A1 (en)
CL (1) CL2015003019A1 (en)
EA (1) EA029361B1 (en)
ES (1) ES2640482T3 (en)
HK (1) HK1221459A1 (en)
MA (1) MA38588B1 (en)
MX (1) MX362338B (en)
PH (1) PH12015502411A1 (en)
PL (1) PL2986607T3 (en)
SA (1) SA515361261B1 (en)
SG (1) SG11201508479RA (en)
TW (1) TWI631119B (en)
WO (1) WO2014170821A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2533217T3 (en) 2008-10-07 2015-04-08 Actelion Pharmaceuticals Ltd. Tricyclic oxazolidinone antibiotic compounds
AR102256A1 (en) 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH REPLACEMENT OF AMINOALCOXI
TW201722965A (en) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 Compounds for use in antibacterial applications
CN109071444A (en) 2016-03-16 2018-12-21 拜耳作物科学股份公司 N- (cyanobenzyl) -6- (cyclopropyl-carbonyl amino) -4- (phenyl)-pyridine -2- carboxamide derivative and related compound as pesticide and plant protection product
AR108108A1 (en) 2016-04-14 2018-07-18 Idorsia Pharmaceuticals Ltd ANTIBACTERIAL BIAROMATIC DERIVATIVES WITH REPLACEMENT OF OXETAN-3-ILOXI
GB2550437B (en) 2016-05-20 2021-06-23 Bugworks Res Inc Heterocyclic compounds useful as anti-bacterial agents and method for production
TW201833120A (en) * 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 Aryloxazolidinone antibiotic compounds
EP3284739A1 (en) 2017-07-19 2018-02-21 Bayer CropScience Aktiengesellschaft Substituted (het) aryl compounds as pesticides
WO2019106693A1 (en) 2017-11-29 2019-06-06 Bugworks Research India Pvt Ltd Anti-bacterial heterocyclic compounds and their synthesis
CA3104928A1 (en) 2018-08-13 2020-02-20 F. Hoffmann-La Roche Ag New heterocyclic compounds as monoacylglycerol lipase inhibitors
CR20220104A (en) 2019-09-12 2022-04-20 Hoffmann La Roche 4,4a,5,7,8,8a-hexapyrido[4,3-b][1,4]oxazin-3-one compounds as magl inhibitors
EP4126855B1 (en) * 2020-03-24 2024-04-24 F. Hoffmann-La Roche AG Compounds and their use in the treatment of bacterial infections
CN115785718B (en) * 2022-11-25 2023-08-22 四川大学 Metal coordination antibacterial coating on multi-substrate surface and preparation method thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0297042A1 (en) 1987-06-23 1988-12-28 Ciba-Geigy Ag Substituted penem compounds
DE19802239A1 (en) 1998-01-22 1999-07-29 Bayer Ag New oxazolidinone derivatives useful as antimicrobial agents against Gram-positive and some Gram-negative bacteria, mycobacteria, etc.
AU1026901A (en) 1999-10-29 2001-05-08 Syngenta Participations Ag Novel herbicides
EP1448538A1 (en) 2001-11-15 2004-08-25 Eli Lilly And Company Peroxisome proliferator activated receptor alpha agonists
AR040335A1 (en) 2002-06-26 2005-03-30 Glaxo Group Ltd CYCLLOHEXAN OR CYCLHEXENE COMPOUND, USE OF THE SAME TO PREPARE A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, PROCEDURE AND INTERMEDIATE COMPOUNDS OF UTILITY TO PREPARE SUCH COMPOUND
WO2006102674A2 (en) 2005-03-24 2006-09-28 Microbia, Inc. Diphenylheterocycle cholesterol absorption inhibitors
TW200734311A (en) 2005-11-21 2007-09-16 Astrazeneca Ab New compounds
US7998992B2 (en) 2007-03-30 2011-08-16 Institute Of Medicinal Molecular Design, Inc. Oxazolidinone derivative having inhibitory activity on 11β-hydroxysteroid dehydrogenase type 1
CL2008001003A1 (en) * 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd COMPOUNDS DERIVED FROM OXAZOLIDINONA; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUNDS; AND ITS USE TO PREPARE A MEDICINAL PRODUCT TO TREAT A BACTERIAL INFECTION.
UA104281C2 (en) 2007-12-20 2014-01-27 Фарма Мар, С.А. Antitumoral peptide analogs, process for the preparation thereof and pharmaceutical composition based thereon
CA2713182C (en) 2008-02-20 2016-09-13 Actelion Pharmaceuticals Ltd Azatricyclic antibiotic compounds
TWI429643B (en) 2008-02-22 2014-03-11 Actelion Pharmaceuticals Ltd Oxazolidinone derivatives
KR20110036938A (en) * 2008-08-04 2011-04-12 액테리온 파마슈티칼 리미티드 Tricyclic alkylaminomethyloxazolidinone derivatives
ES2533217T3 (en) 2008-10-07 2015-04-08 Actelion Pharmaceuticals Ltd. Tricyclic oxazolidinone antibiotic compounds
JP2012505201A (en) * 2008-10-10 2012-03-01 アクテリオン ファーマシューティカルズ リミテッド 2-Benzothiophenyl- and 2-naphthyl-oxazolidinones and their Azaisostare analogs
WO2013068948A1 (en) 2011-11-08 2013-05-16 Actelion Pharmaceuticals Ltd 2-oxo-oxazolidin-3,5-diyl antibiotic derivatives

Also Published As

Publication number Publication date
US9527867B2 (en) 2016-12-27
PL2986607T3 (en) 2017-11-30
BR112015026261A8 (en) 2017-12-26
US20160075722A1 (en) 2016-03-17
HK1221459A1 (en) 2017-06-02
EA029361B1 (en) 2018-03-30
ES2640482T3 (en) 2017-11-03
CN105143216A (en) 2015-12-09
TW201516043A (en) 2015-05-01
MA38588A1 (en) 2017-05-31
AR095884A1 (en) 2015-11-18
TWI631119B (en) 2018-08-01
MX2015014576A (en) 2016-03-04
JP6375365B2 (en) 2018-08-15
CN105143216B (en) 2018-04-13
BR112015026261A2 (en) 2017-07-25
CA2907832A1 (en) 2014-10-23
CL2015003019A1 (en) 2016-09-30
EA201501025A1 (en) 2016-08-31
EP2986607A1 (en) 2016-02-24
MX362338B (en) 2019-01-11
SA515361261B1 (en) 2016-06-15
KR20150143720A (en) 2015-12-23
AU2014255326A1 (en) 2015-11-26
PH12015502411A1 (en) 2016-02-22
WO2014170821A1 (en) 2014-10-23
MA38588B1 (en) 2018-04-30
AU2014255326B2 (en) 2018-09-13
JP2016516805A (en) 2016-06-09
EP2986607B1 (en) 2017-06-14

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