CA2905564A1 - A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids - Google Patents

A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids Download PDF

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Publication number
CA2905564A1
CA2905564A1 CA2905564A CA2905564A CA2905564A1 CA 2905564 A1 CA2905564 A1 CA 2905564A1 CA 2905564 A CA2905564 A CA 2905564A CA 2905564 A CA2905564 A CA 2905564A CA 2905564 A1 CA2905564 A1 CA 2905564A1
Authority
CA
Canada
Prior art keywords
electromagnetic radiation
objects
measuring apparatus
microscopic
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2905564A
Other languages
English (en)
French (fr)
Inventor
Richard Harry Turner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2905564A1 publication Critical patent/CA2905564A1/en
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/088—Condensers for both incident illumination and transillumination
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/30—Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33—Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/70—Determining position or orientation of objects or cameras
    • G06T7/73—Determining position or orientation of objects or cameras using feature-based methods
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10141—Special mode during image acquisition
    • G06T2207/10152—Varying illumination
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Microscoopes, Condenser (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Image Processing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2905564A 2013-03-15 2014-03-10 A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids Abandoned CA2905564A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361790764P 2013-03-15 2013-03-15
US61/790,764 2013-03-15
PCT/IB2014/059581 WO2014141034A2 (en) 2013-03-15 2014-03-10 A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids

Publications (1)

Publication Number Publication Date
CA2905564A1 true CA2905564A1 (en) 2014-09-18

Family

ID=51538221

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2905564A Abandoned CA2905564A1 (en) 2013-03-15 2014-03-10 A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids

Country Status (10)

Country Link
US (1) US10032270B2 (https=)
EP (1) EP2973408A4 (https=)
JP (1) JP2016522880A (https=)
CN (1) CN105492887A (https=)
AU (1) AU2014229420A1 (https=)
BR (1) BR112015023081A2 (https=)
CA (1) CA2905564A1 (https=)
EA (1) EA201591800A1 (https=)
SG (2) SG10201707599WA (https=)
WO (1) WO2014141034A2 (https=)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015029032A1 (en) 2013-08-26 2015-03-05 Parasight Ltd. Digital microscopy systems, methods and computer program products
JP6537332B2 (ja) * 2014-04-28 2019-07-03 キヤノン株式会社 画像処理方法および撮影装置
CN107851031B (zh) * 2015-05-08 2021-05-28 佛罗乔有限责任公司 数据发现节点
US10488644B2 (en) 2015-09-17 2019-11-26 S.D. Sight Diagnostics Ltd. Methods and apparatus for detecting an entity in a bodily sample
WO2017066487A1 (en) * 2015-10-14 2017-04-20 Manta Instructions, Inc. Apparatus and method for measurements of growth or dissolution kinetics of colloidal particles
JP2017142118A (ja) * 2016-02-09 2017-08-17 株式会社イシダ 光検査装置
CA3018536A1 (en) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Distinguishing between blood sample components
KR102497849B1 (ko) * 2016-05-09 2023-02-07 삼성전자주식회사 분석물질 농도 예측 방법 및 장치
WO2017195205A1 (en) 2016-05-11 2017-11-16 S.D. Sight Diagnostics Ltd Sample carrier for optical measurements
EP3455626B1 (en) 2016-05-11 2025-08-06 S.D. Sight Diagnostics Ltd. Performing optical measurements on a sample
EP3279635B1 (en) * 2016-08-04 2022-06-01 Malvern Panalytical Limited Method, processor and machine-readable, non-transient storage medium for characterising particles suspended in a fluid dispersant
EP4357298A3 (en) 2016-12-02 2024-08-07 Molecular Imprints, Inc. Configuring optical layers in imprint lithography processes
US12440193B2 (en) 2017-04-07 2025-10-14 Toi Labs, Inc. System, method and apparatus for forming machine learning sessions
EP3606412A4 (en) * 2017-04-07 2020-12-23 Toi Labs, Inc. BIOSURVEILLANCE DEVICES, METHODS AND SYSTEMS FOR USE IN A BATHROOM LAYOUT
JP6959755B2 (ja) * 2017-04-14 2021-11-05 シスメックス株式会社 蛍光画像分析装置、蛍光画像の分析方法及びコンピュータプログラム
CN107290291A (zh) * 2017-07-02 2017-10-24 广东技术师范学院 双光程调制透射和荧光激发光源测量复杂溶液成分的方法
JP7007122B2 (ja) 2017-07-11 2022-01-24 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
US20210181085A1 (en) * 2017-10-26 2021-06-17 Essenlix Corporation Rapid measurement of platelets
FR3073047B1 (fr) * 2017-11-02 2021-01-29 Commissariat Energie Atomique Procede optique d'estimation d'un volume representatif de particules presentes dans un echantillon
CN111788471B (zh) * 2017-11-14 2023-12-12 思迪赛特诊断有限公司 用于光学测量的样品载体
MX2020006123A (es) 2017-12-15 2020-09-21 Gastroklenz Inc Sistema de monitoreo de sensor para tratamientos basados en cateter permanente.
CN109001191A (zh) * 2018-06-06 2018-12-14 西安纸贵互联网科技有限公司 一种体外诊断试剂的半定量识别方法及装置
CN109235585A (zh) * 2018-09-19 2019-01-18 浙江瑞宝生物科技有限公司 马桶内藏排泄物潜血检测装置及其方法
WO2020076872A1 (en) * 2018-10-08 2020-04-16 Bioelectronica Corporation Systems and methods for optically processing samples
CN111077073A (zh) * 2018-10-19 2020-04-28 深圳迈瑞生物医疗电子股份有限公司 一种样本分析仪
US20200158628A1 (en) * 2018-10-22 2020-05-21 Bioelectronica Corporation Multiplexed assay systems and methods
JP7376245B2 (ja) 2019-03-29 2023-11-08 シスメックス株式会社 蛍光画像分析装置及び蛍光画像分析方法
USD984637S1 (en) 2019-06-26 2023-04-25 Gastroklenz Inc. Measurement vessel
CN114531852A (zh) 2019-06-26 2022-05-24 葛思特克朗兹公司 用于流体监测的系统、装置及方法
USD903126S1 (en) 2019-06-26 2020-11-24 Gastroklenz Inc. Monitoring device
CN110426335B (zh) * 2019-09-05 2022-03-22 苏州大学 一种基于原子力显微镜的纳米颗粒浓度测量方法
AU2020370212B2 (en) 2019-10-22 2025-09-25 S.D. Sight Diagnostics Ltd Accounting for errors in optical measurements
CN114787625B (zh) 2019-12-12 2026-01-13 思迪赛特诊断有限公司 检测血液样品中的血小板
JP7677972B2 (ja) 2019-12-12 2025-05-15 エス．ディー．サイト ダイアグノスティックス リミテッド カラー血液スミア画像の人工的な生成
BR112022011312A2 (pt) 2019-12-12 2022-08-23 S D Sight Diagnostics Ltd Análise de um analito disposto dentro de um meio
CN110940621B (zh) * 2019-12-19 2020-09-15 西安交通大学 一种基于红外技术的凝结液珠形态的识别方法
US10823662B1 (en) * 2020-02-18 2020-11-03 Horiba Instruments, Incorporated Special purpose cuvette assembly and method for optical microscopy of nanoparticle colloids
EP3933479A1 (en) * 2020-07-03 2022-01-05 Leica Microsystems CMS GmbH Microscope for microscopic examination of a sample
CN113340894B (zh) * 2021-05-28 2023-04-07 上海睿钰生物科技有限公司 一种非透明微粒的检测方法
CN119968567A (zh) 2022-10-14 2025-05-09 爱科来株式会社 信息处理装置、信息处理方法和信息处理程序
JP2026017219A (ja) * 2024-07-23 2026-02-04 富士フイルム株式会社 観察装置及び観察方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4592089A (en) 1983-08-15 1986-05-27 Bio Image Corporation Electrophoretogram analytical image processing system
US5134662A (en) 1985-11-04 1992-07-28 Cell Analysis Systems, Inc. Dual color camera microscope and methodology for cell staining and analysis
US4998284A (en) 1987-11-17 1991-03-05 Cell Analysis Systems, Inc. Dual color camera microscope and methodology for cell staining and analysis
US4965725B1 (en) * 1988-04-08 1996-05-07 Neuromedical Systems Inc Neural network based automated cytological specimen classification system and method
AU677780B2 (en) 1992-05-01 1997-05-08 Trustees Of The University Of Pennsylvania, The Microfabricated detection structures
US5889881A (en) 1992-10-14 1999-03-30 Oncometrics Imaging Corp. Method and apparatus for automatically detecting malignancy-associated changes
CA2411465C (en) 2000-06-08 2013-08-27 The Regents Of The University Of California Visual-servoing optical microscopy
JP4133319B2 (ja) * 2000-07-14 2008-08-13 ノバダック テクノロジーズ インコーポレイテッド コンパクトな蛍光内視鏡映像システム
US6993169B2 (en) * 2001-01-11 2006-01-31 Trestle Corporation System and method for finding regions of interest for microscopic digital montage imaging
JP2003075725A (ja) 2001-09-04 2003-03-12 Olympus Optical Co Ltd 透過照明装置
EP1595136A1 (en) * 2003-02-06 2005-11-16 Koninklijke Philips Electronics N.V. Apparatus and method for blood analysis
EP2305173B1 (en) * 2003-03-28 2016-05-11 Inguran, LLC Apparatus and methods for providing sorted particles
DE102005052752A1 (de) * 2005-11-04 2007-05-10 Clondiag Chip Technologies Gmbh Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen
EP2752874A1 (en) * 2004-06-07 2014-07-09 Fluidigm Corporation Method and apparatus for imaging a device under temperature control
US20060066850A1 (en) 2004-09-29 2006-03-30 Fuji Photo Film Co., Ltd. Light measuring device, biochemical analyzer, biochemical analysis method, and spectrophotometer
JP2006098227A (ja) 2004-09-29 2006-04-13 Fuji Photo Film Co Ltd 反射光測定装置及び生化学分析装置
JP2006238802A (ja) * 2005-03-03 2006-09-14 Olympus Corp 細胞観察装置、細胞観察方法、顕微鏡システム、及び細胞観察プログラム
AU2006247747A1 (en) 2005-05-11 2006-11-23 Embrex, Inc. Competitive particle immunoassay methods utilizing fluorescence microscopy
TWI330380B (en) * 2006-12-07 2010-09-11 Nat Univ Tsing Hua A specimen kit for electron microscope and its fabrication process
CA2580589C (en) * 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
US7738094B2 (en) * 2007-01-26 2010-06-15 Becton, Dickinson And Company Method, system, and compositions for cell counting and analysis
TWI320856B (en) * 2007-03-26 2010-02-21 Asia Optical Co Inc Optical apparatus with dual illuminating devices
NZ582786A (en) 2007-07-23 2012-09-28 Clondiag Gmbh Assays for nucleic acids
AT508102A1 (de) 2009-04-08 2010-10-15 Photonic Optische Geraete Gmbh Beleuchtungseinrichtung
US8570370B2 (en) * 2009-08-31 2013-10-29 Bio-Rad Laboratories, Inc. Compact automated cell counter
FR2951542B1 (fr) * 2009-10-16 2011-12-02 Commissariat Energie Atomique Procede de detection optique d'objets micrometriques en solution
WO2011087894A1 (en) * 2010-01-15 2011-07-21 Qbc Diagnostics, Inc. Fluorescent microscope slide
US9743020B2 (en) * 2010-03-23 2017-08-22 California Institute Of Technology Super resolution optofluidic microscopes for 2D and 3D imaging
US9224031B2 (en) * 2010-05-21 2015-12-29 Chemometec A/S Compact dark field light source and dark field image analysis at low magnification
JP5703609B2 (ja) * 2010-07-02 2015-04-22 ソニー株式会社 顕微鏡及び領域判定方法
CN103154662A (zh) * 2010-10-26 2013-06-12 加州理工学院 扫描投影无透镜显微镜系统
US9437393B2 (en) * 2012-11-16 2016-09-06 Protochips, Inc. Method for forming an electrical connection to an sample support in an electron microscope holder
EP2972227B1 (en) * 2013-03-12 2020-05-06 Ventana Medical Systems, Inc. Digitally enhanced microscopy for multiplexed histology

Also Published As

Publication number Publication date
JP2016522880A (ja) 2016-08-04
EP2973408A4 (en) 2017-06-14
AU2014229420A1 (en) 2015-09-24
US10032270B2 (en) 2018-07-24
BR112015023081A2 (pt) 2017-07-18
SG10201707599WA (en) 2017-10-30
US20160042507A1 (en) 2016-02-11
WO2014141034A3 (en) 2015-12-17
WO2014141034A2 (en) 2014-09-18
CN105492887A (zh) 2016-04-13
SG11201506786VA (en) 2015-09-29
EP2973408A2 (en) 2016-01-20
EA201591800A1 (ru) 2016-04-29

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20190312