CA2905223A1 - Anti-il-4 antibodies and bispecific antibodies and uses thereof - Google Patents
Anti-il-4 antibodies and bispecific antibodies and uses thereof Download PDFInfo
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- CA2905223A1 CA2905223A1 CA2905223A CA2905223A CA2905223A1 CA 2905223 A1 CA2905223 A1 CA 2905223A1 CA 2905223 A CA2905223 A CA 2905223A CA 2905223 A CA2905223 A CA 2905223A CA 2905223 A1 CA2905223 A1 CA 2905223A1
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| JP6952605B2 (ja) | 2015-04-24 | 2021-10-20 | ジェネンテック， インコーポレイテッド | 多特異性抗原結合タンパク質 |
| KR20180048731A (ko) * | 2015-08-20 | 2018-05-10 | 제넨테크, 인크. | 재조합 폴리펩티드를 제조하기 위한 fkpa의 정제 및 그의 용도 |
| TWI703158B (zh) * | 2015-09-18 | 2020-09-01 | 美商希佛隆公司 | 特異性結合tl1a之抗體 |
| CN105664178B (zh) * | 2015-09-24 | 2019-08-20 | 洪健 | Syk作为肝纤维化/硬化治疗靶点的应用 |
| EP3383430A4 (en) * | 2015-12-02 | 2019-12-18 | Agenus Inc. | ANTIBODIES AND METHOD FOR USE THEREOF |
| WO2017189805A1 (en) | 2016-04-27 | 2017-11-02 | Abbvie Inc. | Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies |
| CN107446045A (zh) * | 2016-07-22 | 2017-12-08 | 北京天广实生物技术股份有限公司 | 一种抗her2的抗体、其药物组合物及用途 |
| US10377833B2 (en) | 2016-07-22 | 2019-08-13 | Beijing Mabworks Biotech Co., Ltd. | Bispecific anti-HER2 antibody |
| JP6995844B2 (ja) | 2016-09-23 | 2022-02-04 | ジェネンテック， インコーポレイテッド | アトピー性皮膚炎を治療するためのｉｌ－１３アンタゴニストの使用 |
| MA46770A (fr) | 2016-11-09 | 2019-09-18 | Agenus Inc | Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation |
| US20200093764A1 (en) * | 2017-02-07 | 2020-03-26 | Children's Hospital Medical Center | Treatment of asthma with cysteamine |
| US11053309B2 (en) | 2017-08-04 | 2021-07-06 | Regeneron Pharmaceuticals, Inc. | Methods for treating active eosinophilic esophagitis |
| TWI848953B (zh) | 2018-06-09 | 2024-07-21 | 德商百靈佳殷格翰國際股份有限公司 | 針對癌症治療之多特異性結合蛋白 |
| WO2020092015A1 (en) | 2018-11-02 | 2020-05-07 | University Of Rochester | Therapeutic mitigation of epithelial infection |
| CN109593773B (zh) * | 2018-11-22 | 2021-07-30 | 北京利德曼生化股份有限公司 | 一种应用酵母表达系统表达可溶性生长刺激表达基因2蛋白的方法 |
| CN111518211B (zh) | 2018-12-25 | 2022-06-21 | 江苏荃信生物医药股份有限公司 | 抗人白介素4受体α单克隆抗体的制药用途 |
| CA3129963A1 (en) | 2019-03-06 | 2020-09-10 | Regeneron Pharmaceuticals, Inc. | Il-4/il-13 pathway inhibitors for enhanced efficacy in treating cancer |
| MX2021011141A (es) | 2019-03-21 | 2022-01-19 | Regeneron Pharma | Combinacion de inhibidores de la via de il-4/il-13 y ablacion de celulas plasmaticas para el tratamiento de alergia. |
| CN120204385A (zh) * | 2019-05-24 | 2025-06-27 | 赛诺菲 | 治疗系统性硬化症的方法 |
| KR102697769B1 (ko) * | 2020-09-14 | 2024-08-23 | 아주대학교산학협력단 | 인터루킨-4 수용체 알파 서브유닛과 인터루킨-5 수용체 알파 서브유닛에 동시에 결합하는 이중특이항체 및 이의 용도 |
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| CN118355034A (zh) | 2021-12-30 | 2024-07-16 | 瑞泽恩制药公司 | 施用il-4/il-13拮抗剂以减弱特应性进程的方法 |
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| JP5620626B2 (ja) * | 2005-03-31 | 2014-11-05 | 中外製薬株式会社 | 会合制御によるポリペプチド製造方法 |
| EP2050764A1 (en) * | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
| DK2285408T3 (en) * | 2008-06-05 | 2019-02-04 | Ablynx Nv | AMINO ACID SEQUENCES AGAINST COATING PROTEINS IN A VIRUS AND POLYPEPTIDES INCLUDING THESE FOR TREATMENT OF VIRUSAL DISEASES |
| AU2010233994A1 (en) * | 2009-04-07 | 2011-09-22 | Roche Glycart Ag | Bispecific anti-ErbB-3/anti-c-Met antibodies |
| EA201190275A1 (ru) * | 2009-05-28 | 2012-11-30 | Глаксо Груп Лимитед | Белок, связывающий интерлейкин-13 (il-13) |
| DK2560683T4 (da) * | 2010-04-23 | 2022-08-29 | Hoffmann La Roche | Fremstilling af heteromultimeriske proteiner |
-
2014
- 2014-04-04 BR BR112015024553A patent/BR112015024553A2/pt not_active Application Discontinuation
- 2014-04-04 MX MX2015013901A patent/MX2015013901A/es unknown
- 2014-04-04 AR ARP140101485A patent/AR095774A1/es unknown
- 2014-04-04 KR KR1020157031454A patent/KR20150139905A/ko not_active Withdrawn
- 2014-04-04 RU RU2015141529A patent/RU2015141529A/ru not_active Application Discontinuation
- 2014-04-04 JP JP2016506649A patent/JP2016522168A/ja active Pending
- 2014-04-04 CN CN201480031775.3A patent/CN105307676A/zh active Pending
- 2014-04-04 WO PCT/US2014/032998 patent/WO2014165771A2/en not_active Ceased
- 2014-04-04 HK HK16109143.9A patent/HK1220919A1/zh unknown
- 2014-04-04 CA CA2905223A patent/CA2905223A1/en not_active Abandoned
- 2014-04-04 EP EP14779789.8A patent/EP2981286A4/en not_active Withdrawn
- 2014-04-07 TW TW103112741A patent/TW201518321A/zh unknown
-
2015
- 2015-09-18 US US14/858,251 patent/US20160207995A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20160207995A1 (en) | 2016-07-21 |
| RU2015141529A (ru) | 2017-05-15 |
| AR095774A1 (es) | 2015-11-11 |
| JP2016522168A (ja) | 2016-07-28 |
| BR112015024553A2 (pt) | 2017-10-24 |
| TW201518321A (zh) | 2015-05-16 |
| WO2014165771A3 (en) | 2014-11-27 |
| CN105307676A (zh) | 2016-02-03 |
| EP2981286A2 (en) | 2016-02-10 |
| MX2015013901A (es) | 2015-12-11 |
| HK1220919A1 (zh) | 2017-05-19 |
| KR20150139905A (ko) | 2015-12-14 |
| EP2981286A4 (en) | 2016-08-24 |
| WO2014165771A2 (en) | 2014-10-09 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20180404 |