CA2904052A1 - Methods of treating b2-bradykinin receptor mediated angioedema - Google Patents

Info

Publication number

CA2904052A1

CA2904052A1 CA2904052A CA2904052A CA2904052A1 CA 2904052 A1 CA2904052 A1 CA 2904052A1 CA 2904052 A CA2904052 A CA 2904052A CA 2904052 A CA2904052 A CA 2904052A CA 2904052 A1 CA2904052 A1 CA 2904052A1

Authority

CA

Canada

Prior art keywords

methyl

methylquinolin

oxymethyl

dichloro

phenyl

Prior art date

2013-03-14

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Abandoned

Links

• Espacenet
• Global Dossier
• CIPO
• Discuss

• 101710085045 B2 bradykinin receptor Proteins 0.000 title claims abstract description 51
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• 238000000034 method Methods 0.000 title claims abstract description 50
• 230000001404 mediated effect Effects 0.000 title claims abstract description 33
• 208000028185 Angioedema Diseases 0.000 title claims abstract description 28
• 239000000203 mixture Substances 0.000 claims abstract description 111
• -1 quinolone compound Chemical class 0.000 claims abstract description 82
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• QXZGBUJJYSLZLT-FDISYFBBSA-N bradykinin Chemical compound NC(=N)NCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1[C@H](C(=O)NCC(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CO)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)CCC1 QXZGBUJJYSLZLT-FDISYFBBSA-N 0.000 claims description 28
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