CA2903382A1 - Procedes et systemes de traitement micro-fluidique ameliore - Google Patents

Procedes et systemes de traitement micro-fluidique ameliore Download PDF

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Publication number
CA2903382A1
CA2903382A1 CA2903382A CA2903382A CA2903382A1 CA 2903382 A1 CA2903382 A1 CA 2903382A1 CA 2903382 A CA2903382 A CA 2903382A CA 2903382 A CA2903382 A CA 2903382A CA 2903382 A1 CA2903382 A1 CA 2903382A1
Authority
CA
Canada
Prior art keywords
cartridge
fluid
microfluidic
molecule
actuator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2903382A
Other languages
English (en)
Inventor
Daniel Laser
Amy Droitcour
Hailemariam NEGUSSIE
William BEHNKE-PARKS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WAVE 80 BIOSCIENCES Inc
Original Assignee
WAVE 80 BIOSCIENCES Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WAVE 80 BIOSCIENCES Inc filed Critical WAVE 80 BIOSCIENCES Inc
Publication of CA2903382A1 publication Critical patent/CA2903382A1/fr
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0418—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Micromachines (AREA)

Abstract

La présente invention concerne des procédés et des systèmes pour une cartouche micro-fluidique comprenant un actionneur haute performance utile pour la détection d'analyte, l'étiquetage et l'analyse. Les systèmes de traitement micro-fluidique servent à effectuer des réactions chimiques ou biochimiques, ou des séquences de réactions, à l'aide de petits volumes de réactifs et de produits (habituellement, entre 1 microlitre et 10 millilitres). Un système de traitement micro-fluidique peut comprendre un réseau de tubes interfacés avec des éléments individuels tels que des vannes et des capteurs, ou un dispositif intégré fabriqué en plastique, verre, métal, ou d'autres matériaux, ou une combinaison de matériaux, avec des éléments tels que des vannes et des capteurs intégrés dans le dispositif et connectés par des passages d'écoulement formés dans le matériau.
CA2903382A 2013-03-01 2014-03-03 Procedes et systemes de traitement micro-fluidique ameliore Abandoned CA2903382A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361771708P 2013-03-01 2013-03-01
US61/771,708 2013-03-01
PCT/US2014/020029 WO2014137940A1 (fr) 2013-03-01 2014-03-03 Procédés et systèmes de traitement micro-fluidique amélioré

Publications (1)

Publication Number Publication Date
CA2903382A1 true CA2903382A1 (fr) 2014-09-12

Family

ID=51491830

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2903382A Abandoned CA2903382A1 (fr) 2013-03-01 2014-03-03 Procedes et systemes de traitement micro-fluidique ameliore

Country Status (4)

Country Link
EP (1) EP2962092A4 (fr)
JP (2) JP2016516562A (fr)
CA (1) CA2903382A1 (fr)
WO (1) WO2014137940A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017066884A1 (fr) * 2015-10-23 2017-04-27 The Royal Institution For The Advancement Of Learning/Mcgill University Circuits fluidiques et procédés de criblage bactérien

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105758942B (zh) * 2014-12-16 2019-01-04 中国科学院大连化学物理研究所 基于多种核酸适体的多蛋白同时在线富集检测方法
CN105241941A (zh) * 2015-09-06 2016-01-13 常州大学 一种毛细管内快速检测酶浓度的方法
WO2018025899A1 (fr) * 2016-08-03 2018-02-08 和光純薬工業株式会社 Solution pour remplir un dispositif microfluidique en plastique
JP6759841B2 (ja) * 2016-08-15 2020-09-23 住友ゴム工業株式会社 マイクロ流路チップ
US11865540B2 (en) * 2016-09-23 2024-01-09 Hewlett-Packard Development Company, L.P. Microfluidic device
PL235210B1 (pl) * 2016-12-21 2020-06-15 Genomtec Spolka Akcyjna Sposób detekcji materiału genetycznego w próbce biologicznej oraz urządzenie do jego realizacji
JP6863074B2 (ja) * 2017-05-24 2021-04-21 住友ゴム工業株式会社 マイクロ流路チップ
CA3078976A1 (fr) * 2017-11-09 2019-05-16 Visby Medical, Inc. Dispositif de diagnostic moleculaire portatif et procedes de detection de virus cibles
US10046322B1 (en) * 2018-03-22 2018-08-14 Talis Biomedical Corporation Reaction well for assay device
CN109576345A (zh) * 2018-10-17 2019-04-05 西人马（厦门）科技有限公司 一种用于dna提取的微流控芯片及其检测方法
US11008627B2 (en) 2019-08-15 2021-05-18 Talis Biomedical Corporation Diagnostic system
KR102329337B1 (ko) * 2020-01-21 2021-11-19 (주)옵토레인 푸시타입 pcr용 카트리지
CN116930298B (zh) * 2023-09-14 2023-12-26 古镜科技(深圳)有限公司 用于检测hiv的电化学生物传感器及其制备方法和应用

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EP0907412B1 (fr) * 1996-06-28 2008-08-27 Caliper Life Sciences, Inc. Systeme de dosage de criblage a fort rendement dans des dispositifs microscopiques de transfert de fluides
US5800690A (en) * 1996-07-03 1998-09-01 Caliper Technologies Corporation Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forces
US6391622B1 (en) * 1997-04-04 2002-05-21 Caliper Technologies Corp. Closed-loop biochemical analyzers
US6416642B1 (en) * 1999-01-21 2002-07-09 Caliper Technologies Corp. Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection
US6670153B2 (en) * 2000-09-14 2003-12-30 Caliper Technologies Corp. Microfluidic devices and methods for performing temperature mediated reactions
US7214300B2 (en) * 2001-06-04 2007-05-08 Epocal Inc. Integrated electrokinetic devices and methods of manufacture
US7235164B2 (en) * 2002-10-18 2007-06-26 Eksigent Technologies, Llc Electrokinetic pump having capacitive electrodes
NL1023404C2 (nl) * 2003-05-13 2004-11-16 Berkin Bv Inrichting voor het regelen van het massadebiet van een vloeistofstroom in een vloeistofkanaal.
US7316543B2 (en) 2003-05-30 2008-01-08 The Board Of Trustees Of The Leland Stanford Junior University Electroosmotic micropump with planar features
US20050034990A1 (en) * 2003-08-12 2005-02-17 Crooks Richard M. System and method for electrokinetic trapping and concentration enrichment of analytes in a microfluidic channel
JP4593373B2 (ja) * 2004-06-07 2010-12-08 ナノフュージョン株式会社 電気浸透流ポンプシステム及び電気浸透流ポンプ
CN101939644B (zh) * 2008-01-10 2014-06-11 休雷尔公司 免疫系统模拟装置和方法
JP2012508894A (ja) * 2008-11-13 2012-04-12 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マイクロ流体システムの流入口と毛細管チャネルとの接続
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JP2012251927A (ja) * 2011-06-06 2012-12-20 National Institute Of Advanced Industrial & Technology 標的物質検出用マイクロチップ

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017066884A1 (fr) * 2015-10-23 2017-04-27 The Royal Institution For The Advancement Of Learning/Mcgill University Circuits fluidiques et procédés de criblage bactérien

Also Published As

Publication number Publication date
EP2962092A4 (fr) 2016-08-24
JP2016516562A (ja) 2016-06-09
JP2019162623A (ja) 2019-09-26
WO2014137940A1 (fr) 2014-09-12
EP2962092A1 (fr) 2016-01-06

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190228

FZDE Discontinued

Effective date: 20220110

FZDE Discontinued

Effective date: 20220110