CA2900949A1 - Treatment of pediatric growth hormone deficiency with human growth hormone analogues - Google Patents
Treatment of pediatric growth hormone deficiency with human growth hormone analogues Download PDFInfo
- Publication number
- CA2900949A1 CA2900949A1 CA2900949A CA2900949A CA2900949A1 CA 2900949 A1 CA2900949 A1 CA 2900949A1 CA 2900949 A CA2900949 A CA 2900949A CA 2900949 A CA2900949 A CA 2900949A CA 2900949 A1 CA2900949 A1 CA 2900949A1
- Authority
- CA
- Canada
- Prior art keywords
- days
- hgh
- xten
- fusion protein
- bolus dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361776618P | 2013-03-11 | 2013-03-11 | |
| US61/776,618 | 2013-03-11 | ||
| US201361810786P | 2013-04-11 | 2013-04-11 | |
| US61/810,786 | 2013-04-11 | ||
| US201361835002P | 2013-06-14 | 2013-06-14 | |
| US61/835,002 | 2013-06-14 | ||
| US201361880701P | 2013-09-20 | 2013-09-20 | |
| US61/880,701 | 2013-09-20 | ||
| US201361911731P | 2013-12-04 | 2013-12-04 | |
| US61/911,731 | 2013-12-04 | ||
| US201461931987P | 2014-01-27 | 2014-01-27 | |
| US61/931,987 | 2014-01-27 | ||
| US201461948457P | 2014-03-05 | 2014-03-05 | |
| US61/948,457 | 2014-03-05 | ||
| PCT/US2014/022850 WO2014164568A1 (en) | 2013-03-11 | 2014-03-10 | Treatment of pediatric growth hormone deficiency with human growth hormone analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2900949A1 true CA2900949A1 (en) | 2014-10-09 |
Family
ID=51658905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2900949A Abandoned CA2900949A1 (en) | 2013-03-11 | 2014-03-10 | Treatment of pediatric growth hormone deficiency with human growth hormone analogues |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20160158321A1 (enExample) |
| EP (1) | EP2968451A4 (enExample) |
| JP (3) | JP2016514132A (enExample) |
| KR (1) | KR20150124955A (enExample) |
| CN (1) | CN105209055A (enExample) |
| AU (1) | AU2014249258A1 (enExample) |
| BR (1) | BR112015022257A8 (enExample) |
| CA (1) | CA2900949A1 (enExample) |
| CL (1) | CL2015002456A1 (enExample) |
| EA (1) | EA201591529A1 (enExample) |
| HK (1) | HK1216617A1 (enExample) |
| IL (1) | IL240392A0 (enExample) |
| MX (1) | MX2015012175A (enExample) |
| PH (1) | PH12015502063A1 (enExample) |
| SG (1) | SG11201506732YA (enExample) |
| WO (1) | WO2014164568A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9849188B2 (en) | 2009-06-08 | 2017-12-26 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
| WO2016109823A1 (en) * | 2015-01-02 | 2016-07-07 | Amunix Operation Inc. | Treatment of pediatric growth hormone deficiency with human growth hormone analogues |
| WO2016124817A1 (en) | 2015-02-03 | 2016-08-11 | Beddit Oy | Family sleep monitoring system |
| IL319047A (en) | 2015-08-28 | 2025-04-01 | Amunix Operating Inc | Chimeric polypeptide composition and methods for its preparation and use |
| WO2017136583A1 (en) | 2016-02-02 | 2017-08-10 | Versartis, Inc. | Growth hormone treatment adherence system |
| EP3416677B1 (en) | 2016-02-17 | 2022-08-03 | Genexine, Inc. | Pharmaceutical composition comprising recombinant hgh for the treatment of growth hormone deficiency |
| CN118105512A (zh) * | 2016-08-30 | 2024-05-31 | 株式会社吉耐森 | 含有hGH融合蛋白的治疗生长激素缺乏症的药物组合物 |
| US10288629B1 (en) * | 2017-12-19 | 2019-05-14 | Aeterna Zentaris, Inc. | Method of assessing growth hormone deficiency in humans by a macimorelin containing composition |
| KR20260039804A (ko) | 2017-12-21 | 2026-03-20 | 아뮤닉스 파마슈티컬스, 인크. | 유리 세그먼트 및 이것을 포함하는 결합 조성물 |
| US11903683B2 (en) | 2018-08-03 | 2024-02-20 | Chelak Medical Solutions Inc | Non-barometric determination of hemodynamic effects of cardiac arrhythmias using signals sensed by an implantable device |
| RU2753191C2 (ru) * | 2019-09-26 | 2021-08-12 | Федеральное государственное бюджетное учреждение науки Институт Биологии Развития им. Н.К. Кольцова Российской Академии Наук | Новый рекомбинантный аналог гормона роста пролонгированного действия |
| WO2021136223A1 (en) | 2019-12-31 | 2021-07-08 | Beijing Ql Biopharmaceutical Co., Ltd. | Fusion proteins of glp-1 and gdf15 and conjugates thereof |
| CN113728013B (zh) | 2020-01-11 | 2022-06-14 | 北京质肽生物医药科技有限公司 | Glp-1和fgf21的融合蛋白的缀合物 |
| KR102599111B1 (ko) * | 2020-01-31 | 2023-11-07 | 울산대학교 산학협력단 | 인슐린유사성장인자-1 융합단백질 및 이의 용도 |
| CN114258492A (zh) * | 2020-07-22 | 2022-03-29 | 阿特纳赞塔里斯有限公司 | 一种通过使用马昔瑞林诊断儿科患者中生长激素缺乏症的筛选方法 |
| CA3193453A1 (en) | 2020-09-30 | 2022-04-07 | Beijing Ql Biopharmaceutical Co., Ltd. | Polypeptide conjugates and methods of uses |
| EP4323413A4 (en) | 2022-03-30 | 2025-10-15 | Beijing Ql Biopharmaceutical Co Ltd | LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3178835T3 (da) * | 2009-02-03 | 2019-06-24 | Amunix Pharmaceuticals Inc | Forlængede rekombinante polypeptider og sammensætninger omfattende samme |
| ES2544982T3 (es) * | 2009-09-02 | 2015-09-07 | Merck Serono S.A. | Método para predecir el nivel de respuesta al crecimiento |
| CN107320719A (zh) * | 2012-06-05 | 2017-11-07 | 阿穆尼克斯运营公司 | Hgh‑xten融合蛋白及其在治疗生长激素缺乏中的用途 |
-
2014
- 2014-03-10 WO PCT/US2014/022850 patent/WO2014164568A1/en not_active Ceased
- 2014-03-10 EA EA201591529A patent/EA201591529A1/ru unknown
- 2014-03-10 US US14/771,445 patent/US20160158321A1/en not_active Abandoned
- 2014-03-10 SG SG11201506732YA patent/SG11201506732YA/en unknown
- 2014-03-10 AU AU2014249258A patent/AU2014249258A1/en not_active Abandoned
- 2014-03-10 EP EP14780175.7A patent/EP2968451A4/en not_active Withdrawn
- 2014-03-10 KR KR1020157023667A patent/KR20150124955A/ko not_active Withdrawn
- 2014-03-10 CA CA2900949A patent/CA2900949A1/en not_active Abandoned
- 2014-03-10 CN CN201480011475.9A patent/CN105209055A/zh active Pending
- 2014-03-10 HK HK16104695.2A patent/HK1216617A1/zh unknown
- 2014-03-10 BR BR112015022257A patent/BR112015022257A8/pt active Search and Examination
- 2014-03-10 JP JP2016501088A patent/JP2016514132A/ja not_active Withdrawn
- 2014-03-10 MX MX2015012175A patent/MX2015012175A/es unknown
-
2015
- 2015-08-06 IL IL240392A patent/IL240392A0/en unknown
- 2015-09-02 CL CL2015002456A patent/CL2015002456A1/es unknown
- 2015-09-11 PH PH12015502063A patent/PH12015502063A1/en unknown
-
2017
- 2017-03-02 JP JP2017039625A patent/JP2017101074A/ja not_active Withdrawn
-
2019
- 2019-01-17 JP JP2019005944A patent/JP2019056013A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR112015022257A2 (pt) | 2017-10-10 |
| MX2015012175A (es) | 2016-01-12 |
| CL2015002456A1 (es) | 2016-05-27 |
| IL240392A0 (en) | 2015-09-24 |
| BR112015022257A8 (pt) | 2018-01-23 |
| EA201591529A1 (ru) | 2016-04-29 |
| SG11201506732YA (en) | 2015-09-29 |
| US20160158321A1 (en) | 2016-06-09 |
| JP2019056013A (ja) | 2019-04-11 |
| CN105209055A (zh) | 2015-12-30 |
| WO2014164568A1 (en) | 2014-10-09 |
| HK1216617A1 (zh) | 2016-11-25 |
| EP2968451A4 (en) | 2017-01-04 |
| JP2016514132A (ja) | 2016-05-19 |
| AU2014249258A1 (en) | 2015-08-27 |
| JP2017101074A (ja) | 2017-06-08 |
| EP2968451A1 (en) | 2016-01-20 |
| PH12015502063A1 (en) | 2016-01-25 |
| KR20150124955A (ko) | 2015-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20190312 |