CA2892053C - Multi-layer device for selectively determining magnesium ion - Google Patents

Multi-layer device for selectively determining magnesium ion Download PDF

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Publication number
CA2892053C
CA2892053C CA2892053A CA2892053A CA2892053C CA 2892053 C CA2892053 C CA 2892053C CA 2892053 A CA2892053 A CA 2892053A CA 2892053 A CA2892053 A CA 2892053A CA 2892053 C CA2892053 C CA 2892053C
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Prior art keywords
luminoionophore
hydrogen
cation
group
alkyl
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CA2892053A
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English (en)
French (fr)
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CA2892053A1 (en
Inventor
Peter Chaoquan ZHU
Yingzi Wu
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Opti Medical Systems Inc
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Opti Medical Systems Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Biophysics (AREA)
CA2892053A 2012-11-29 2013-11-20 Multi-layer device for selectively determining magnesium ion Active CA2892053C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/689,350 US9360474B2 (en) 2012-11-29 2012-11-29 Multi-layer device for selectively determining magnesium ion
US13/689,350 2012-11-29
PCT/US2013/071004 WO2014085160A1 (en) 2012-11-29 2013-11-20 Multi-layer device for selectively determining magnesium ion

Publications (2)

Publication Number Publication Date
CA2892053A1 CA2892053A1 (en) 2014-06-05
CA2892053C true CA2892053C (en) 2018-05-29

Family

ID=50773621

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2892053A Active CA2892053C (en) 2012-11-29 2013-11-20 Multi-layer device for selectively determining magnesium ion

Country Status (5)

Country Link
US (1) US9360474B2 (https=)
EP (1) EP2926121B1 (https=)
JP (1) JP6177931B2 (https=)
CA (1) CA2892053C (https=)
WO (1) WO2014085160A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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CN108069966B (zh) * 2016-11-14 2020-03-31 中国科学院大连化学物理研究所 用于snap蛋白标记的小分子荧光探针及其合成方法与应用
CN108069967B (zh) * 2016-11-15 2020-03-27 中国科学院大连化学物理研究所 一种用于细胞内蛋白标记的荧光探针及其合成方法和应用
CN108864046B (zh) * 2018-04-25 2019-11-05 苏州首通科技发展有限公司 Fe2+分子荧光测试液、其制备方法及其应用
CN108675989B (zh) * 2018-04-25 2019-07-02 中国科学院生物物理研究所 Fe3+分子荧光测试剂及其制备方法
CN108801992B (zh) * 2018-04-25 2019-08-02 中国科学院生物物理研究所 Fe3+分子荧光传感器及其制备方法
CN109060733B (zh) * 2018-04-25 2019-11-05 苏州首通科技发展有限公司 铁离子分子荧光传感器及其制备方法
CN111650191A (zh) * 2020-06-12 2020-09-11 吉林基蛋生物科技有限公司 一种抗镁离子干扰的尿液钙离子检测试纸制备方法
CN115073311B (zh) * 2022-03-23 2023-05-23 河南大学 一种高效制备n,n′-二（2羟乙基）苯胺的合成方法
CN117304041A (zh) * 2023-10-09 2023-12-29 江苏七禾新材料科技有限公司 一种连续催化加氢制备邻氨基苯酚的方法

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DE2842862A1 (de) 1978-10-02 1980-04-10 Boehringer Mannheim Gmbh Verfahren zur bestimmung von ionen, polaren und/oder lipophilen substanzen in fluessigkeiten
US4603209A (en) 1984-09-07 1986-07-29 The Regents Of The University Of California Fluorescent indicator dyes for calcium ions
IL79087A0 (en) 1985-07-02 1986-09-30 Miles Lab Multilayer ion test means
US5215925A (en) * 1986-04-29 1993-06-01 Eastman Kodak Company Method and composition for magnesium ion detection using hydroxy-substituted cyanoformazans
US4774339A (en) 1987-08-10 1988-09-27 Molecular Probes, Inc. Chemically reactive dipyrrometheneboron difluoride dyes
WO1993008684A1 (en) * 1991-10-28 1993-05-13 Steinman Gary D Process and device for measuring magnesium in biological fluids and method of preparing the device
US5310888A (en) * 1992-10-22 1994-05-10 Miles Inc. Arylazo chromoionophores
US5516911A (en) 1993-12-30 1996-05-14 The United States Of America As Represented By The Department Of Health And Human Services Fluorescent intracellular calcium indicators
JP3809484B2 (ja) * 1996-03-29 2006-08-16 アークレイ株式会社 体液中のマグネシウム測定用試験片
DE69703906T2 (de) * 1996-03-29 2001-06-13 Kyoto Daiichi Kagaku Co. Ltd., Kyoto Vorrichtung zur Messung von Magnesium in biologischen Flüssigkeiten
AT405103B (de) 1996-10-16 1999-05-25 Avl Verbrennungskraft Messtech Sensorschicht zur quantitativen bestimmung zumindest einer chemischen komponente einer gasförmigen oder flüssigen probe
KR100207515B1 (ko) 1996-10-31 1999-07-15 윤종용 Y/c 간섭 제거회로
AT405462B (de) 1997-05-30 1999-08-25 Avl List Gmbh Verfahren zur bestimmung eines alkaliions
US6171866B1 (en) 1998-09-30 2001-01-09 Avl Medical Instruments Luminescence indicator for determining calcium ions
JP2000258414A (ja) * 1999-03-08 2000-09-22 Fuji Photo Film Co Ltd 一体型多層化学分析要素および定量方法
AU774336B2 (en) 1999-04-27 2004-06-24 Ciphergen Biosystems, Inc. Probes for a gas phase ion spectrometer
US6211359B1 (en) * 1999-08-17 2001-04-03 Avl Medical Instruments Triaza-cryptand and method of determining an alkali ion
US6706528B2 (en) * 2000-03-24 2004-03-16 The United States Of America As Represented By The Department Of Health And Human Services Fluorescent magnesium indicators
US7109043B2 (en) * 2000-07-28 2006-09-19 Japan Science And Technology Corporation Fluorescent probe for magnesium ion determination
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Also Published As

Publication number Publication date
EP2926121A1 (en) 2015-10-07
US9360474B2 (en) 2016-06-07
CA2892053A1 (en) 2014-06-05
EP2926121B1 (en) 2017-02-22
EP2926121A4 (en) 2016-04-27
WO2014085160A1 (en) 2014-06-05
JP6177931B2 (ja) 2017-08-09
JP2016505824A (ja) 2016-02-25
US20140147876A1 (en) 2014-05-29

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