CA2892053C - Multi-layer device for selectively determining magnesium ion - Google Patents

Multi-layer device for selectively determining magnesium ion Download PDF

Info

Publication number
CA2892053C
CA2892053C CA2892053A CA2892053A CA2892053C CA 2892053 C CA2892053 C CA 2892053C CA 2892053 A CA2892053 A CA 2892053A CA 2892053 A CA2892053 A CA 2892053A CA 2892053 C CA2892053 C CA 2892053C
Authority
CA
Canada
Prior art keywords
luminoionophore
hydrogen
cation
group
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2892053A
Other languages
English (en)
French (fr)
Other versions
CA2892053A1 (en
Inventor
Peter Chaoquan ZHU
Yingzi Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Opti Medical Systems Inc
Original Assignee
Opti Medical Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opti Medical Systems Inc filed Critical Opti Medical Systems Inc
Publication of CA2892053A1 publication Critical patent/CA2892053A1/en
Application granted granted Critical
Publication of CA2892053C publication Critical patent/CA2892053C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Biophysics (AREA)
CA2892053A 2012-11-29 2013-11-20 Multi-layer device for selectively determining magnesium ion Active CA2892053C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/689,350 US9360474B2 (en) 2012-11-29 2012-11-29 Multi-layer device for selectively determining magnesium ion
US13/689,350 2012-11-29
PCT/US2013/071004 WO2014085160A1 (en) 2012-11-29 2013-11-20 Multi-layer device for selectively determining magnesium ion

Publications (2)

Publication Number Publication Date
CA2892053A1 CA2892053A1 (en) 2014-06-05
CA2892053C true CA2892053C (en) 2018-05-29

Family

ID=50773621

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2892053A Active CA2892053C (en) 2012-11-29 2013-11-20 Multi-layer device for selectively determining magnesium ion

Country Status (5)

Country Link
US (1) US9360474B2 (enExample)
EP (1) EP2926121B1 (enExample)
JP (1) JP6177931B2 (enExample)
CA (1) CA2892053C (enExample)
WO (1) WO2014085160A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108069966B (zh) * 2016-11-14 2020-03-31 中国科学院大连化学物理研究所 用于snap蛋白标记的小分子荧光探针及其合成方法与应用
CN108069967B (zh) * 2016-11-15 2020-03-27 中国科学院大连化学物理研究所 一种用于细胞内蛋白标记的荧光探针及其合成方法和应用
CN109060733B (zh) * 2018-04-25 2019-11-05 苏州首通科技发展有限公司 铁离子分子荧光传感器及其制备方法
CN108801992B (zh) * 2018-04-25 2019-08-02 中国科学院生物物理研究所 Fe3+分子荧光传感器及其制备方法
CN108675989B (zh) * 2018-04-25 2019-07-02 中国科学院生物物理研究所 Fe3+分子荧光测试剂及其制备方法
CN108864046B (zh) * 2018-04-25 2019-11-05 苏州首通科技发展有限公司 Fe2+分子荧光测试液、其制备方法及其应用
CN111650191A (zh) * 2020-06-12 2020-09-11 吉林基蛋生物科技有限公司 一种抗镁离子干扰的尿液钙离子检测试纸制备方法
CN115073311B (zh) * 2022-03-23 2023-05-23 河南大学 一种高效制备n,n′-二（2羟乙基）苯胺的合成方法
CN117304041A (zh) * 2023-10-09 2023-12-29 江苏七禾新材料科技有限公司 一种连续催化加氢制备邻氨基苯酚的方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2842862A1 (de) 1978-10-02 1980-04-10 Boehringer Mannheim Gmbh Verfahren zur bestimmung von ionen, polaren und/oder lipophilen substanzen in fluessigkeiten
US4603209A (en) 1984-09-07 1986-07-29 The Regents Of The University Of California Fluorescent indicator dyes for calcium ions
IL79087A0 (en) 1985-07-02 1986-09-30 Miles Lab Multilayer ion test means
US5215925A (en) * 1986-04-29 1993-06-01 Eastman Kodak Company Method and composition for magnesium ion detection using hydroxy-substituted cyanoformazans
US4774339A (en) 1987-08-10 1988-09-27 Molecular Probes, Inc. Chemically reactive dipyrrometheneboron difluoride dyes
WO1993008684A1 (en) 1991-10-28 1993-05-13 Steinman Gary D Process and device for measuring magnesium in biological fluids and method of preparing the device
US5310888A (en) * 1992-10-22 1994-05-10 Miles Inc. Arylazo chromoionophores
US5516911A (en) 1993-12-30 1996-05-14 The United States Of America As Represented By The Department Of Health And Human Services Fluorescent intracellular calcium indicators
JP3809484B2 (ja) * 1996-03-29 2006-08-16 アークレイ株式会社 体液中のマグネシウム測定用試験片
CN1107229C (zh) * 1996-03-29 2003-04-30 株式会社京都第一科学 用于测定生物体液中镁的测试片
AT405103B (de) 1996-10-16 1999-05-25 Avl Verbrennungskraft Messtech Sensorschicht zur quantitativen bestimmung zumindest einer chemischen komponente einer gasförmigen oder flüssigen probe
KR100207515B1 (ko) 1996-10-31 1999-07-15 윤종용 Y/c 간섭 제거회로
AT405462B (de) 1997-05-30 1999-08-25 Avl List Gmbh Verfahren zur bestimmung eines alkaliions
US6171866B1 (en) 1998-09-30 2001-01-09 Avl Medical Instruments Luminescence indicator for determining calcium ions
JP2000258414A (ja) * 1999-03-08 2000-09-22 Fuji Photo Film Co Ltd 一体型多層化学分析要素および定量方法
DE60045816D1 (de) 1999-04-27 2011-05-19 Bio Rad Laboratories Probenhalter für ein gasphaseionenspektrometer
US6211359B1 (en) * 1999-08-17 2001-04-03 Avl Medical Instruments Triaza-cryptand and method of determining an alkali ion
US6706528B2 (en) * 2000-03-24 2004-03-16 The United States Of America As Represented By The Department Of Health And Human Services Fluorescent magnesium indicators
AU2002229152A1 (en) * 2000-07-28 2002-02-18 Japan Science And Technology Corporation Fluorescent probe for magnesium ion determination
AU7918501A (en) 2000-08-04 2002-02-18 Molecular Probes Inc Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings
JP5090731B2 (ja) * 2004-03-04 2012-12-05 哲雄 長野 蛍光プローブ
US8097725B2 (en) 2004-12-03 2012-01-17 Roche Diagnostics Operations, Inc. Luminescent indicator dye and optical sensor
US20070259438A1 (en) 2006-05-03 2007-11-08 Opti Medical Systems, Inc. Chromoionophore and method of determining calcium ions
KR100858560B1 (ko) * 2007-05-25 2008-09-16 고려대학교 산학협력단 세포질 내 마그네슘의 실시간 모니터링용 이광자 염료, 그제조방법 및 이를 이용한 세포질 내 마그네슘의 실시간모니터링 방법

Also Published As

Publication number Publication date
WO2014085160A1 (en) 2014-06-05
EP2926121B1 (en) 2017-02-22
JP6177931B2 (ja) 2017-08-09
US9360474B2 (en) 2016-06-07
EP2926121A1 (en) 2015-10-07
JP2016505824A (ja) 2016-02-25
EP2926121A4 (en) 2016-04-27
CA2892053A1 (en) 2014-06-05
US20140147876A1 (en) 2014-05-29

Similar Documents

Publication Publication Date Title
EP2926121B1 (en) Multi-layer device for selectively determining magnesium ion
JP4808777B2 (ja) 非揮発性アナライト濃度の測定方法
US6124135A (en) Method of determining an alkali ion
JP2606721B2 (ja) 色原体クリプタヘミスフエランドと水性検査試料中の電解質検出へのその使用
AU617097B2 (en) Compounds, reagents and procedures for determining cations
KR100232439B1 (ko) 생물학적 샘플내 단백질 지시제로서 니트로 또는 니트로소 치환된 폴리할로겐화 페놀설폰프탈레인, 이를 포함하는 시험 스트립 및 이를 사용한 단백질 검출 방법
Donghan et al. Fluorescence turn off-on continuous response of dual lanthanide metal organic frameworks for selective detecting fluoroquinolone antibiotics
KR102513508B1 (ko) pH 검출용 염료 화합물, 이를 이용한 필름 및 키트
US6211359B1 (en) Triaza-cryptand and method of determining an alkali ion
CN115894293A (zh) 一种检测肼的比率型近红外荧光探针及其合成方法与应用
Orellana et al. Environmental and industrial optosensing with tailored luminescent Ru (II) polypyridyl complexes
CN109060733A (zh) 铁离子分子荧光传感器及其制备方法
US6610848B1 (en) Platinum complex dioxygen sensors
CN116496233B (zh) 一种具有聚集诱导发光性质的pH荧光探针及其制备和应用
US5096831A (en) Reagents for determining cations
US5045475A (en) Reagent for determining cations
EP4711422A1 (en) Dyes with ph-dependent absorption and fluorescence
Wolfbeis et al. Solid state supramolecular optical sensors
US5145787A (en) Method for determining the concentration of cations in a sample
KR100232446B1 (ko) 메로시아닌 단백오차 지시제를 함유하는 단백질 검출용 시험 스트립
CN114163423A (zh) 可实现癌细胞筛选的谷胱甘肽比率可逆荧光探针、制备方法与应用
WOLFBEIS et al. University of Regensburg, Institute of Analytical Chemistry, Chemo-and Biosensors, 93040 Regensburg, Germany
US5073501A (en) Method for determining the concentration of cations in a sample
CN120904084A (zh) 一种基于ict机制的近红外荧光探针dci-tso及制备方法和应用
CN110981804A (zh) 一种快速响应的过氧化亚硝酸盐荧光探针、制备方法与应用

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20170105

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 11TH ANNIV.) - STANDARD

Year of fee payment: 11

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20241115

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 11TH ANNIV.) - STANDARD

Year of fee payment: 11

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250501

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250501

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250922

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 12TH ANNIV.) - STANDARD

Year of fee payment: 12

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20251028

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20251028

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-4-4-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20251031