CA2890171C - A porous silica material for use as a pharmaceutical or dietary active ingredient - Google Patents

A porous silica material for use as a pharmaceutical or dietary active ingredient Download PDF

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Publication number
CA2890171C
CA2890171C CA2890171A CA2890171A CA2890171C CA 2890171 C CA2890171 C CA 2890171C CA 2890171 A CA2890171 A CA 2890171A CA 2890171 A CA2890171 A CA 2890171A CA 2890171 C CA2890171 C CA 2890171C
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CA
Canada
Prior art keywords
range
pores
formulation
pore size
dietary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2890171A
Other languages
English (en)
French (fr)
Other versions
CA2890171A1 (en
Inventor
Robert CSIKASZ
Tore Bengtsson
Natalia KUPFERSCHMIDT
Alfonso E. Garcia-Bennett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIGRID THERAPEUTICS AB
Original Assignee
SIGRID THERAPEUTICS AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SIGRID THERAPEUTICS AB filed Critical SIGRID THERAPEUTICS AB
Priority to CA3024640A priority Critical patent/CA3024640A1/en
Publication of CA2890171A1 publication Critical patent/CA2890171A1/en
Application granted granted Critical
Publication of CA2890171C publication Critical patent/CA2890171C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/015—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/12—Surface area
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/14—Pore volume
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/16—Pore diameter
    • C01P2006/17—Pore diameter distribution
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Silicon Compounds (AREA)
CA2890171A 2012-11-06 2013-11-06 A porous silica material for use as a pharmaceutical or dietary active ingredient Active CA2890171C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3024640A CA3024640A1 (en) 2012-11-06 2013-11-06 A porous silica material for use as a pharmaceutical or dietary active ingredient

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261723019P 2012-11-06 2012-11-06
US61/723,019 2012-11-06
PCT/EP2013/073200 WO2014072363A1 (en) 2012-11-06 2013-11-06 A porous silica material for use as a pharmaceutical or dietary active ingredient

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3024640A Division CA3024640A1 (en) 2012-11-06 2013-11-06 A porous silica material for use as a pharmaceutical or dietary active ingredient

Publications (2)

Publication Number Publication Date
CA2890171A1 CA2890171A1 (en) 2014-05-15
CA2890171C true CA2890171C (en) 2019-01-22

Family

ID=49639855

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2890171A Active CA2890171C (en) 2012-11-06 2013-11-06 A porous silica material for use as a pharmaceutical or dietary active ingredient
CA3024640A Abandoned CA3024640A1 (en) 2012-11-06 2013-11-06 A porous silica material for use as a pharmaceutical or dietary active ingredient
CA3024460A Pending CA3024460A1 (fr) 2012-11-06 2018-11-15 A porous silica material for use as a pharmaceutical or dietary active ingredient

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA3024640A Abandoned CA3024640A1 (en) 2012-11-06 2013-11-06 A porous silica material for use as a pharmaceutical or dietary active ingredient
CA3024460A Pending CA3024460A1 (fr) 2012-11-06 2018-11-15 A porous silica material for use as a pharmaceutical or dietary active ingredient

Country Status (20)

Country Link
US (2) US10695294B2 (enExample)
EP (2) EP3892285A3 (enExample)
JP (2) JP6421124B2 (enExample)
CN (2) CN113069467A (enExample)
AU (1) AU2013343565B2 (enExample)
BR (1) BR112015010118A2 (enExample)
CA (3) CA2890171C (enExample)
CY (1) CY1124471T1 (enExample)
DK (1) DK2916852T3 (enExample)
ES (1) ES2878017T3 (enExample)
HR (1) HRP20211036T1 (enExample)
HU (1) HUE055017T2 (enExample)
IL (1) IL238538B (enExample)
LT (1) LT2916852T (enExample)
PH (1) PH12015501010B1 (enExample)
PL (1) PL2916852T3 (enExample)
PT (1) PT2916852T (enExample)
SI (1) SI2916852T1 (enExample)
WO (1) WO2014072363A1 (enExample)
ZA (1) ZA201502979B (enExample)

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* Cited by examiner, † Cited by third party
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CA2890171C (en) 2012-11-06 2019-01-22 Sigrid Therapeutics Ab A porous silica material for use as a pharmaceutical or dietary active ingredient
ES2643057T3 (es) * 2012-12-21 2017-11-21 National Health Research Institutes Nanopartículas mesóporas de sílice para la absorción de aceite
US20200129444A1 (en) * 2017-07-13 2020-04-30 Carnegie Mellon University Method of Increasing Epithelial Permeability Using Nanoparticles
WO2019116258A1 (en) * 2017-12-13 2019-06-20 L.I.Co.Rice S.R.L. Complex of lactoferrin and silica, process for preparing and compositions for oral hygiene
GB201803363D0 (en) * 2018-03-01 2018-04-18 Sigrid Therapeutics Ab New materials and uses thereof
WO2020212418A1 (en) * 2019-04-15 2020-10-22 Nanologica Ab Empty porous particles for use in treatment, prevention and/or postponement of degeneration of neurodegenerative diseases, neurons and glia.
CN110314151B (zh) * 2019-08-02 2020-06-02 深圳国佳产业基金管理有限公司 医用介孔二氧化硅材料及其应用
EP4038162A4 (en) * 2019-09-30 2023-10-25 Zeroignition Technologies Inc. THERMAL INSULATING AND FIRE-RETARDANT MATERIAL AND ITS MANUFACTURING METHOD
JP7578945B2 (ja) * 2020-10-27 2024-11-07 信越化学工業株式会社 イミダゾールシラン処理シリカからなる胆汁酸吸着剤
CN114195885B (zh) * 2022-01-12 2024-04-26 杭州隆基生物技术有限公司 一种单克隆抗体组合物提纯方法
EP4472602A1 (en) 2022-02-04 2024-12-11 Sigrid Therapeutics AB Oral care composition comprising porous silica particles
JP2025119063A (ja) 2022-04-28 2025-08-14 日本たばこ産業株式会社 無機多孔質材料を含む口腔用組成物
GB202212239D0 (en) 2022-08-23 2022-10-05 Sigrid Therapeutics Ab New dietary supplements
GB202212240D0 (en) 2022-08-23 2022-10-05 Sigrid Therapeutics Ab New formulations and medical uses thereof
CN116747321B (zh) * 2023-06-14 2025-09-05 厦门君德医药科技有限公司 一种接枝改性的介孔二氧化硅及其制备方法和应用
GB202312176D0 (en) 2023-08-09 2023-09-20 Sigrid Therapeutics Ab New uses and methods
GB202312179D0 (en) 2023-08-09 2023-09-20 Sigrid Therapeutics Ab New compositions and uses

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AU7881000A (en) * 1999-08-16 2001-03-13 Henceforth Hibernia, Inc. Therapeutic and prophylactic compositions including catalytic biomimetic solids and methods to prepare and use them
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GB201212866D0 (en) 2012-07-20 2012-09-05 Formac Pharmaceuticals Nv Dry granulates of mesoporous silica powders
CA2890171C (en) 2012-11-06 2019-01-22 Sigrid Therapeutics Ab A porous silica material for use as a pharmaceutical or dietary active ingredient
US10835495B2 (en) 2012-11-14 2020-11-17 W. R. Grace & Co.-Conn. Compositions containing a biologically active material and a non-ordered inorganic oxide material and methods of making and using the same
ES2643057T3 (es) 2012-12-21 2017-11-21 National Health Research Institutes Nanopartículas mesóporas de sílice para la absorción de aceite

Also Published As

Publication number Publication date
US20150258028A1 (en) 2015-09-17
SI2916852T1 (sl) 2021-08-31
PL2916852T3 (pl) 2021-11-02
PT2916852T (pt) 2021-06-15
IL238538B (en) 2019-06-30
DK2916852T3 (en) 2021-05-10
EP3892285A3 (en) 2021-11-17
AU2013343565A1 (en) 2015-05-21
JP6752858B2 (ja) 2020-09-09
CA3024460A1 (fr) 2018-11-15
ES2878017T3 (es) 2021-11-18
US12121612B2 (en) 2024-10-22
HRP20211036T1 (hr) 2021-10-01
JP6421124B2 (ja) 2018-11-07
US10695294B2 (en) 2020-06-30
CN113069467A (zh) 2021-07-06
BR112015010118A2 (pt) 2017-07-11
EP2916852A1 (en) 2015-09-16
LT2916852T (lt) 2021-06-25
AU2013343565B2 (en) 2018-07-26
US20200390703A1 (en) 2020-12-17
JP2019023222A (ja) 2019-02-14
ZA201502979B (en) 2024-09-25
HUE055017T2 (hu) 2021-10-28
CA2890171A1 (en) 2014-05-15
PH12015501010A1 (en) 2015-07-27
EP3892285A2 (en) 2021-10-13
CY1124471T1 (el) 2022-07-22
WO2014072363A1 (en) 2014-05-15
EP2916852B1 (en) 2021-04-14
CN105188720A (zh) 2015-12-23
CA3024640A1 (en) 2014-05-15
IL238538A0 (en) 2015-06-30
JP2015536939A (ja) 2015-12-24
PH12015501010B1 (en) 2023-10-20

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