CA2885240A1 - Novel mva virus and uses thereof - Google Patents

Novel mva virus and uses thereof Download PDF

Info

Publication number
CA2885240A1
CA2885240A1 CA2885240A CA2885240A CA2885240A1 CA 2885240 A1 CA2885240 A1 CA 2885240A1 CA 2885240 A CA2885240 A CA 2885240A CA 2885240 A CA2885240 A CA 2885240A CA 2885240 A1 CA2885240 A1 CA 2885240A1
Authority
CA
Canada
Prior art keywords
amino acid
gene product
virus
cell
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2885240A
Other languages
English (en)
French (fr)
Inventor
Ingo Jordan
Volker Sandig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ProBioGen AG
Original Assignee
ProBioGen AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ProBioGen AG filed Critical ProBioGen AG
Publication of CA2885240A1 publication Critical patent/CA2885240A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24061Methods of inactivation or attenuation
    • C12N2710/24064Methods of inactivation or attenuation by serial passage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24121Viruses as such, e.g. new isolates, mutants or their genomic sequences

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2885240A 2012-09-28 2012-09-28 Novel mva virus and uses thereof Abandoned CA2885240A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2012/069256 WO2014048500A1 (en) 2012-09-28 2012-09-28 Novel mva virus and uses thereof

Publications (1)

Publication Number Publication Date
CA2885240A1 true CA2885240A1 (en) 2014-04-03

Family

ID=46982581

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2885240A Abandoned CA2885240A1 (en) 2012-09-28 2012-09-28 Novel mva virus and uses thereof

Country Status (12)

Country Link
US (1) US9732325B2 (enExample)
EP (1) EP2900810B1 (enExample)
JP (1) JP2015535687A (enExample)
CN (1) CN104812894B (enExample)
AU (1) AU2012391162A1 (enExample)
BR (1) BR112015006798A2 (enExample)
CA (1) CA2885240A1 (enExample)
DK (1) DK2900810T3 (enExample)
IN (1) IN2015DN02335A (enExample)
MX (1) MX2015003687A (enExample)
RU (1) RU2015115898A (enExample)
WO (1) WO2014048500A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11104884B2 (en) 2017-02-23 2021-08-31 Probiogen Ab Vaccinia virus vectors related to MVA with extensive genomic symmetries
JP7551496B2 (ja) 2017-10-31 2024-09-17 カリヴィル イムノセラピューティクス, インコーポレイテッド 全身送達のためのプラットフォーム腫瘍溶解性ベクター
CN108371715A (zh) * 2018-01-03 2018-08-07 肖小林 一种病毒的靶向性防治药物
JP2021535730A (ja) * 2018-05-11 2021-12-23 シティ・オブ・ホープCity of Hope 複数の部位メガロウイルス(cmv)抗原の発現のためのmvaベクター及びその使用
CN112384615A (zh) 2018-07-04 2021-02-19 普罗拜奥根股份公司 用于纯化包膜病毒的方法
WO2022109133A1 (en) 2020-11-19 2022-05-27 Kalivir Immunotherapeutics, Inc. Oncolytic immunotherapy by tumor micro-environment remodeling
WO2023128672A1 (ko) * 2021-12-29 2023-07-06 재단법인 아산사회복지재단 외피외 바이러스 생산이 증가한 신규한 백시니아 바이러스 변이주
WO2023223183A1 (en) 2022-05-16 2023-11-23 Crispr Therapeutics Ag Picornaviral vectors for gene editing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7645456B2 (en) 2001-04-23 2010-01-12 Sanofi Pasteur Biologics Co. Vaccinia virus strains
WO2005048957A2 (en) 2003-02-20 2005-06-02 Therion Biologics Corporation Novel insertion sites in pox vectors

Also Published As

Publication number Publication date
DK2900810T3 (en) 2019-04-29
IN2015DN02335A (enExample) 2015-08-28
CN104812894A (zh) 2015-07-29
WO2014048500A1 (en) 2014-04-03
US9732325B2 (en) 2017-08-15
MX2015003687A (es) 2015-06-15
JP2015535687A (ja) 2015-12-17
BR112015006798A2 (pt) 2017-11-21
RU2015115898A (ru) 2016-11-20
EP2900810A1 (en) 2015-08-05
EP2900810B1 (en) 2019-02-20
CN104812894B (zh) 2021-10-22
US20150299666A1 (en) 2015-10-22
AU2012391162A1 (en) 2015-04-09

Similar Documents

Publication Publication Date Title
US9732325B2 (en) MVA virus and uses thereof
JP5783642B2 (ja) Mvaの主なゲノム欠失を含むワクシニアウイルス変異体
TW575664B (en) Recombinant MVA virus, and the use thereof
MX2008015166A (es) Proceso para producir poxvirus y composiciones de poxvirus.
KR20130030298A (ko) 불멸화 조류 세포주들
BRPI0215003B1 (pt) método para a recuperação e purificação de poxvírus a partir de células infectadas
CN103088049A (zh) 日本脑炎病毒sa14-14-2株基于dna的感染性克隆、其构建方法及应用
Jordan et al. A chemically defined production process for highly attenuated poxviruses
Léon et al. The EB66® cell line as a valuable cell substrate for MVA-based vaccines production
US11104884B2 (en) Vaccinia virus vectors related to MVA with extensive genomic symmetries
US11999975B2 (en) Method for purifying an enveloped virus
Melamed et al. Attenuation and immunogenicity of host-range extended modified vaccinia virus Ankara recombinants
US20060216312A1 (en) Mutants of replication competent vaccinia virus
JP2006509526A (ja) トリ胚性幹細胞上におけるalvacの産生
KR20250156704A (ko) 메추라기 세포 배양을 통한 폭스바이러스 생산
WO2024188801A1 (en) Use of quail cell lines for poxvirus production
AU2024280931A9 (en) Rapid selection system for the generation of recombinant enveloped viruses
AU2024280931A1 (en) Rapid selection system for the generation of recombinant enveloped viruses
WO2024245721A1 (en) Diploid recombinant nucleocytoplasmic large dna viral vectors
Ricci Generation of modified vaccinia virus ankara recombinants by rescue of the essential D4R gene
EP2199385A1 (en) Specific and persistent activation of heat shock response in cell lines using a viral factor

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20180928