CA2884897C - Method of treatment or prophylaxis of infections of the eye - Google Patents

Method of treatment or prophylaxis of infections of the eye Download PDF

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Publication number
CA2884897C
CA2884897C CA2884897A CA2884897A CA2884897C CA 2884897 C CA2884897 C CA 2884897C CA 2884897 A CA2884897 A CA 2884897A CA 2884897 A CA2884897 A CA 2884897A CA 2884897 C CA2884897 C CA 2884897C
Authority
CA
Canada
Prior art keywords
integer
dendrimer
eye
macromolecule
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2884897A
Other languages
English (en)
French (fr)
Other versions
CA2884897A1 (en
Inventor
Jacinth Kincaid Fairley
Colin Paul Barrett
Jeremy Robert Arthur PAULL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Starpharma Pty Ltd
Original Assignee
Starpharma Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Starpharma Pty Ltd filed Critical Starpharma Pty Ltd
Publication of CA2884897A1 publication Critical patent/CA2884897A1/en
Application granted granted Critical
Publication of CA2884897C publication Critical patent/CA2884897C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/795Polymers containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2884897A 2012-09-13 2013-09-13 Method of treatment or prophylaxis of infections of the eye Active CA2884897C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261700714P 2012-09-13 2012-09-13
US61/700,714 2012-09-13
PCT/US2013/059810 WO2014043576A1 (en) 2012-09-13 2013-09-13 Method of treatment or prophylaxis of infections of the eye

Publications (2)

Publication Number Publication Date
CA2884897A1 CA2884897A1 (en) 2014-03-20
CA2884897C true CA2884897C (en) 2021-07-27

Family

ID=50278734

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2884897A Active CA2884897C (en) 2012-09-13 2013-09-13 Method of treatment or prophylaxis of infections of the eye

Country Status (9)

Country Link
US (2) US10149885B2 (cg-RX-API-DMAC7.html)
EP (1) EP2895161B1 (cg-RX-API-DMAC7.html)
JP (2) JP6419701B2 (cg-RX-API-DMAC7.html)
CN (2) CN105007910B (cg-RX-API-DMAC7.html)
CA (1) CA2884897C (cg-RX-API-DMAC7.html)
DK (1) DK2895161T3 (cg-RX-API-DMAC7.html)
ES (1) ES2633778T3 (cg-RX-API-DMAC7.html)
IN (1) IN2015DN02233A (cg-RX-API-DMAC7.html)
WO (1) WO2014043576A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009008006A2 (en) * 2007-07-06 2009-01-15 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
RU2667118C1 (ru) * 2017-11-15 2018-09-14 Федеральное государственное бюджетное научное учреждение "Прикаспийский зональный научно-исследовательский ветеринарный институт" Универсальное средство в виде мази для комплексного лечения глазных болезней животных и способ его получения
CN110664757B (zh) * 2018-11-19 2022-08-02 成都瑞沐生物医药科技有限公司 纳米晶滴眼剂、其制备方法及其应用
GB2599799B (en) * 2020-04-15 2023-04-05 Starpharma Pty Ltd Macromolecule for prophylaxis of Coronavirus

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPM623994A0 (en) * 1994-06-15 1994-07-07 Biomolecular Research Institute Limited Antiviral dendrimers
PL345544A1 (en) * 1998-07-14 2001-12-17 Upjohn Co Oxazolidinones to treat eye infections
AUPP584298A0 (en) 1998-09-14 1998-10-08 Starpharma Limited Antimicrobial and antiparasitic agents
AUPR412801A0 (en) * 2001-03-30 2001-05-03 Starpharma Limited Agent for the prevention and treatment of sexually transmitted disease s - I
WO2005007223A2 (en) * 2003-07-16 2005-01-27 Sasha John Programmable medical drug delivery systems and methods for delivery of multiple fluids and concentrations
EP1755616B1 (en) * 2004-04-08 2013-08-14 Advanced Ocular Systems Limited Treatment of exudative retinopathy with mineralcorticoids
RU2396962C2 (ru) 2005-10-18 2010-08-20 Старфарма Пти Лимитед Система доставки микробицидных дендримерных композиций
PL1940916T3 (pl) * 2005-10-25 2017-07-31 Starpharma Pty Limited Związki wielocząsteczkowe o kontrolowanej stechiometrii
US8568790B2 (en) * 2006-05-31 2013-10-29 Medihoney Pty Ltd. Medicinal compositions containing honey
JP5484339B2 (ja) * 2007-10-05 2014-05-07 ウェイン ステート ユニバーシティー 合成物の持続的な放出のためのデンドリマー
BRPI1008602A8 (pt) * 2009-02-18 2018-01-02 Eyeon Particle Sciences Llc uso de co-polímero bi-funcional para as aplicações oftálmicas e outras aplicações tópicas e locais
WO2011003876A1 (en) * 2009-07-07 2011-01-13 Adenovir Pharma Ab New antiviral compounds useful for the treatment or the prevention of epidemic keratoconjonctivitis
SI2709633T1 (sl) 2011-05-16 2020-01-31 Starpharma Pty Ltd Metoda zdravljenja ali profilaksa bakterijske vaginoze

Also Published As

Publication number Publication date
CN105007910B (zh) 2019-03-19
HK1212619A1 (en) 2016-06-17
EP2895161A1 (en) 2015-07-22
EP2895161A4 (en) 2016-03-23
JP6766114B2 (ja) 2020-10-07
JP2019001827A (ja) 2019-01-10
JP6419701B2 (ja) 2018-11-07
EP2895161B1 (en) 2017-05-03
ES2633778T3 (es) 2017-09-25
CN105007910A (zh) 2015-10-28
US10149885B2 (en) 2018-12-11
CN108452316A (zh) 2018-08-28
CN108452316B (zh) 2022-04-15
IN2015DN02233A (cg-RX-API-DMAC7.html) 2015-08-21
US20190070249A1 (en) 2019-03-07
JP2015528509A (ja) 2015-09-28
CA2884897A1 (en) 2014-03-20
DK2895161T3 (en) 2017-08-21
US20150238557A1 (en) 2015-08-27
US11219691B2 (en) 2022-01-11
WO2014043576A1 (en) 2014-03-20

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Effective date: 20180913