CA2882558C - Mineral-enzyme complex for strengthening and whitening tooth enamel, oral hygiene composition, and toothpaste - Google Patents
Mineral-enzyme complex for strengthening and whitening tooth enamel, oral hygiene composition, and toothpaste Download PDFInfo
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- CA2882558C CA2882558C CA2882558A CA2882558A CA2882558C CA 2882558 C CA2882558 C CA 2882558C CA 2882558 A CA2882558 A CA 2882558A CA 2882558 A CA2882558 A CA 2882558A CA 2882558 C CA2882558 C CA 2882558C
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- 235000019820 disodium diphosphate Nutrition 0.000 description 1
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- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 description 1
- 235000021242 lactoferrin Nutrition 0.000 description 1
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- 229940057428 lactoperoxidase Drugs 0.000 description 1
- 235000011477 liquorice Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
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- 244000005700 microbiome Species 0.000 description 1
- 244000005706 microflora Species 0.000 description 1
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- 229940074371 monofluorophosphate Drugs 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
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- 239000002736 nonionic surfactant Substances 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- ZVVSSOQAYNYNPP-UHFFFAOYSA-N olaflur Chemical compound F.F.CCCCCCCCCCCCCCCCCCN(CCO)CCCN(CCO)CCO ZVVSSOQAYNYNPP-UHFFFAOYSA-N 0.000 description 1
- 229960001245 olaflur Drugs 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 235000011197 perejil Nutrition 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 229940068977 polysorbate 20 Drugs 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- OQZCJRJRGMMSGK-UHFFFAOYSA-M potassium metaphosphate Chemical compound [K+].[O-]P(=O)=O OQZCJRJRGMMSGK-UHFFFAOYSA-M 0.000 description 1
- 229940099402 potassium metaphosphate Drugs 0.000 description 1
- ZNNZYHKDIALBAK-UHFFFAOYSA-M potassium thiocyanate Chemical compound [K+].[S-]C#N ZNNZYHKDIALBAK-UHFFFAOYSA-M 0.000 description 1
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- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 229940112950 sage extract Drugs 0.000 description 1
- 235000020752 sage extract Nutrition 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
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- 230000007017 scission Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 1
- 235000019983 sodium metaphosphate Nutrition 0.000 description 1
- 229940060304 sodium myristoyl sarcosinate Drugs 0.000 description 1
- KHCOJQDJOCNUGV-UHFFFAOYSA-M sodium;2-[methyl(tetradecanoyl)amino]acetate Chemical compound [Na+].CCCCCCCCCCCCCC(=O)N(C)CC([O-])=O KHCOJQDJOCNUGV-UHFFFAOYSA-M 0.000 description 1
- IXMINYBUNCWGER-UHFFFAOYSA-M sodium;4-propoxycarbonylphenolate Chemical compound [Na+].CCCOC(=O)C1=CC=C([O-])C=C1 IXMINYBUNCWGER-UHFFFAOYSA-M 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
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- 239000000725 suspension Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
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- 229920001059 synthetic polymer Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- RYCLIXPGLDDLTM-UHFFFAOYSA-J tetrapotassium;phosphonato phosphate Chemical compound [K+].[K+].[K+].[K+].[O-]P([O-])(=O)OP([O-])([O-])=O RYCLIXPGLDDLTM-UHFFFAOYSA-J 0.000 description 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 1
- 229940061605 tetrasodium glutamate diacetate Drugs 0.000 description 1
- UZVUJVFQFNHRSY-OUTKXMMCSA-J tetrasodium;(2s)-2-[bis(carboxylatomethyl)amino]pentanedioate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CC[C@@H](C([O-])=O)N(CC([O-])=O)CC([O-])=O UZVUJVFQFNHRSY-OUTKXMMCSA-J 0.000 description 1
- 238000004861 thermometry Methods 0.000 description 1
- 230000036367 tooth discoloration Effects 0.000 description 1
- 230000005086 tooth mineralization Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
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- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2012135577/15A RU2494725C1 (ru) | 2012-08-20 | 2012-08-20 | Минерально-ферментативный комплекс для укрепления и отбеливания эмали зубов, композиция для гигиены полости рта и зубная паста |
| RU2012135577 | 2012-08-20 | ||
| PCT/RU2013/000716 WO2014031035A1 (ru) | 2012-08-20 | 2013-08-19 | Минерально-ферметативный комплекс для укрепления и отбеливания эмали зубов, композиция для гигиены полости рта и зубная паста |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2882558A1 CA2882558A1 (en) | 2014-02-27 |
| CA2882558C true CA2882558C (en) | 2020-07-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2882558A Active CA2882558C (en) | 2012-08-20 | 2013-08-19 | Mineral-enzyme complex for strengthening and whitening tooth enamel, oral hygiene composition, and toothpaste |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20150190329A1 (tr) |
| EP (1) | EP2902008B1 (tr) |
| CN (1) | CN104812360A (tr) |
| CA (1) | CA2882558C (tr) |
| EA (1) | EA024261B1 (tr) |
| ES (1) | ES2723923T3 (tr) |
| HK (1) | HK1212907A1 (tr) |
| IN (1) | IN2015DN02235A (tr) |
| RU (1) | RU2494725C1 (tr) |
| SG (1) | SG11201501290QA (tr) |
| TR (1) | TR201902383T4 (tr) |
| UA (1) | UA113772C2 (tr) |
| WO (1) | WO2014031035A1 (tr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11026873B2 (en) * | 2015-12-31 | 2021-06-08 | Colgate-Palmolive Company | Personal care composition comprising taurine, arginine, glycine |
| EA027690B1 (ru) * | 2016-03-14 | 2017-08-31 | Общество С Ограниченной Ответственностью "Сплат-Косметика" (Ооо "Сплат-Косметика") | Минерально-растительный комплекс для удаления зубного налета, композиция для гигиены полости рта и зубная паста |
| RU2675257C1 (ru) * | 2018-01-09 | 2018-12-18 | Федеральное государственное бюджетное учреждение науки Институт органического синтеза им. И.Я. Постовского Уральского отделения Российской академии наук | Лечебно-профилактическая зубная паста |
| JP2023110105A (ja) * | 2020-05-01 | 2023-08-09 | 株式会社トレスバイオ研究所 | 口腔用組成物 |
| CN112274478A (zh) * | 2020-12-21 | 2021-01-29 | 广东微笑科技有限公司 | 一种含精氨酸护龈牙膏及其制备方法 |
| CN112870115B (zh) * | 2021-02-25 | 2023-04-14 | 中国热带农业科学院热带作物品种资源研究所 | 一种中老年人专效的南药复方牙膏及其制备方法 |
| CN113509394A (zh) * | 2021-07-14 | 2021-10-19 | 上海市第十人民医院 | 一种矿化甘油凝胶、制备方法及应用 |
| CN114469750A (zh) * | 2022-01-28 | 2022-05-13 | 陕西师范大学 | 一种用于治疗牙敏感以及促进牙釉质外延生长的矿化材料及其应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3666627A (en) * | 1968-10-14 | 1972-05-30 | Corning Glass Works | Method of stabilizing enzymes |
| JPH0228563B2 (ja) * | 1986-04-22 | 1990-06-25 | Dental Chem Co Ltd | Hamigakisoseibutsu |
| RU2060030C1 (ru) | 1990-02-14 | 1996-05-20 | Научная фирма "Биосиб" | Зубная паста |
| EP0709452A1 (en) * | 1994-10-27 | 1996-05-01 | The Procter & Gamble Company | Cleaning compositions comprising xylanases |
| RU2131723C1 (ru) * | 1997-08-05 | 1999-06-20 | Открытое акционерное общество косметическое объединение "Свобода" | Лечебно-профилактическая композиция для обработки зубов |
| JP4199333B2 (ja) * | 1998-08-07 | 2008-12-17 | 宇部マテリアルズ株式会社 | 歯磨組成物 |
| AU7924200A (en) * | 2000-03-01 | 2001-09-12 | Lucas Huybrechts | Tooth whitening products and procedures |
| US6652841B1 (en) * | 2002-08-28 | 2003-11-25 | Colgate Palmolive Company | Antiplaque enzyme containing dual component composition |
| US20050271601A1 (en) * | 2004-06-02 | 2005-12-08 | Nebojsa Milanovich | Anti-staining antibacterial dentifrice |
| US20060140881A1 (en) * | 2004-12-22 | 2006-06-29 | Guofeng Xu | Oral care compositions containing flavonoids and flavans |
| JP4697449B2 (ja) * | 2006-05-19 | 2011-06-08 | ライオン株式会社 | 歯牙美白用組成物 |
| FR2915386B1 (fr) * | 2007-04-24 | 2009-08-21 | Pierre Fabre Medicament Sa | Utilisation d'un extrait aqueux de pepins de raisin en association avec au moins un sel de fluor contre la formation ou l'accumulation du biofilm dentaire et les compositions comprenant cette association |
| RU2355420C2 (ru) | 2007-06-29 | 2009-05-20 | Леонид Леонидович Клопотенко | Зубная паста, содержащая лактулозу, бетаин, хондроитин сульфат и ферменты: папаин, лизоцим, рибонуклеазу и лидазу |
| RU2381021C2 (ru) * | 2007-11-12 | 2010-02-10 | Леонид Леонидович Клопотенко | Зубная паста, содержащая липосомы |
| RU2355380C1 (ru) | 2008-01-11 | 2009-05-20 | Сергей Владимирович Сирак | Зубной эликсир для профилактики и лечения начальных форм кариеса зубов |
| EP2095724A1 (en) * | 2008-02-27 | 2009-09-02 | Südzucker Aktiengesellschaft Mannheim/Ochsenfurt | Improved non-cariogenic composite materials and processes for their preparation |
| RU2416391C1 (ru) * | 2009-09-03 | 2011-04-20 | Общество с ограниченной ответственностью "СПЛАТ-КОСМЕТИКА" | Композиция для ухода за полостью рта |
| CN101692998A (zh) * | 2009-10-22 | 2010-04-14 | 浙江大学 | 一种含葡萄籽原花青素提取物的牙膏及应用 |
| JP2011162491A (ja) * | 2010-02-10 | 2011-08-25 | Ezaki Glico Co Ltd | 乾燥麹抽出物及びこれを用いた口腔用組成物 |
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2012
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2013
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- 2013-08-19 WO PCT/RU2013/000716 patent/WO2014031035A1/ru active Application Filing
- 2013-08-19 IN IN2235DEN2015 patent/IN2015DN02235A/en unknown
- 2013-08-19 TR TR2019/02383T patent/TR201902383T4/tr unknown
- 2013-08-19 UA UAA201502464A patent/UA113772C2/uk unknown
- 2013-08-19 EA EA201500145A patent/EA024261B1/ru unknown
- 2013-08-19 CN CN201380044236.9A patent/CN104812360A/zh active Pending
- 2013-08-19 EP EP13830900.0A patent/EP2902008B1/en active Active
- 2013-08-19 SG SG11201501290QA patent/SG11201501290QA/en unknown
- 2013-08-19 US US14/422,985 patent/US20150190329A1/en not_active Abandoned
- 2013-08-19 CA CA2882558A patent/CA2882558C/en active Active
-
2016
- 2016-01-28 HK HK16100925.2A patent/HK1212907A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014031035A1 (ru) | 2014-02-27 |
| CN104812360A (zh) | 2015-07-29 |
| US20150190329A1 (en) | 2015-07-09 |
| HK1212907A1 (zh) | 2016-06-24 |
| UA113772C2 (xx) | 2017-03-10 |
| IN2015DN02235A (tr) | 2015-08-21 |
| ES2723923T3 (es) | 2019-09-03 |
| SG11201501290QA (en) | 2015-04-29 |
| EP2902008A1 (en) | 2015-08-05 |
| CA2882558A1 (en) | 2014-02-27 |
| EP2902008B1 (en) | 2019-02-13 |
| EA201500145A1 (ru) | 2015-06-30 |
| TR201902383T4 (tr) | 2019-03-21 |
| EA024261B1 (ru) | 2016-08-31 |
| RU2494725C1 (ru) | 2013-10-10 |
| EP2902008A4 (en) | 2016-05-18 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20180816 |