CN112274478A - 一种含精氨酸护龈牙膏及其制备方法 - Google Patents

一种含精氨酸护龈牙膏及其制备方法 Download PDF

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CN112274478A
CN112274478A CN202011522629.4A CN202011522629A CN112274478A CN 112274478 A CN112274478 A CN 112274478A CN 202011522629 A CN202011522629 A CN 202011522629A CN 112274478 A CN112274478 A CN 112274478A
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arginine
toothpaste
gingiva
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彭程
黄彪
向卓林
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Guangdong Smile Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/84Products or compounds obtained by lyophilisation, freeze-drying

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Abstract

一种含精氨酸护龈牙膏,由以下按照重量份数计的原材料组成:精氨酸20‑30份,调味剂2‑8份,月桂醇酸钠2份~3份,牙粉2份~5份,益生菌冻干粉2‑7份,谷氨酸钠0.01‑0.05份,甘油8‑10份,蒸馏水20‑30份,黄原胶0.5‑1.5份,摩擦剂10‑15份,将精氨酸、月桂醇酸钠、牙粉、谷氨酸钠、甘油、蒸馏水、和黄原胶加入搅拌机中进行第一次搅拌得到初步混合物,然后再往初步混合物中加入摩擦剂、调味剂和益生菌冻干粉,进行第二次搅拌,得到二次混合物;研磨,真空脱气,得到牙膏膏体。本发明有效去除固有的牙菌斑,达到全面护理口腔,保持牙齿健康,美白牙齿,保护牙龈的作用。

Description

一种含精氨酸护龈牙膏及其制备方法
技术领域
本发明涉及牙膏技术领域,具体地说是一种含精氨酸护龈牙膏及其制备方法。
背景技术
随着人类生活水平的逐渐提高,越来越多的人们对口腔的保健观念和习惯发生了较大变化。同时,现代生活的快节奏、高压力让中国人的口腔状况日渐复杂化、多样化,以含氟牙膏、中草药牙膏、脱敏牙膏为代表的传统功效型牙膏逐渐被细分。从2005年开始,在云南白药牙膏的带动下,相当数量的知名牙膏品牌陆续推出了高端功效牙膏,牙膏的功效、品质、包装得到进一步提升。目前功效型牙膏的功能主要分为两个大类:一是预防和辅助治疗某些口腔疾病,如蛀牙、牙敏感、牙龈炎、牙周炎、口腔溃疡、牙齿缺损等。二是帮助调整和改善口腔状况,如增白牙齿、去口腔异味、去牙结石、去牙渍和牙斑等。未来随着消费者对口腔问题的关注变化和医学机构对口腔状况更深度地了解,还会有一些新的功能需求。如抗口干牙膏、补牙牙膏被挖掘出来。
而目前的多功能性牙膏,作用仍然较为有限。
发明内容
为了解决上述的技术问题,本发明提供了一种含精氨酸护龈牙膏及其制备方法。
为了解决上述技术问题,本发明采取以下技术方案:
一种含精氨酸护龈牙膏,由以下按照重量份数计的原材料组成:
精氨酸20-30份,调味剂2-8份,月桂醇酸钠2份~3份,牙粉2份~5份,益生菌冻干粉2-7份,谷氨酸钠0.01-0.05份,甘油8-10份,蒸馏水20-30份,黄原胶0.5-1.5份,摩擦剂10-15份。
所述调味剂为山梨糖醇、甜菊糖苷和薄荷醇的一种或多种组合。
所述摩擦剂为二氧化硅。
所述二氧化硅的粒径为0.5-30微米。
所述益生菌冻干粉的益生菌种类为唾液乳杆菌。
一种含精氨酸护龈牙膏的制备方法,包括以下步骤:
将精氨酸、月桂醇酸钠、牙粉、谷氨酸钠、甘油、蒸馏水、和黄原胶加入搅拌机中进行第一次搅拌得到初步混合物,然后再往初步混合物中加入摩擦剂、调味剂和益生菌冻干粉,进行第二次搅拌,得到二次混合物;
研磨,真空脱气,得到牙膏膏体。
所述二次混合物还进行PH值调整,将PH值调整为6-8。
所述调节PH值采用柠檬酸或氢氧化钠作为调节剂。
本发明有效去除固有的牙菌斑,达到全面护理口腔,保持牙齿健康,美白牙齿,保护牙龈的作用。
具体实施方式
为能进一步了解本发明的特征、技术手段以及所达到的具体目的、功能,下面结合具体实施方式对本发明作进一步详细描述。
实施例一
一种含精氨酸护龈牙膏,由以下按照重量份数计的原材料组成:
精氨酸15份,甜菊糖苷5份,月桂醇酸钠3份,牙粉3份,益生菌冻干粉5份,谷氨酸钠0.04份,甘油9份,蒸馏水25份,黄原胶0.1份,摩擦剂12份。所述二氧化硅的粒径为15微米。
所述益生菌冻干粉的益生菌种类为唾液乳杆菌。
一种含精氨酸护龈牙膏的制备方法,包括以下步骤:
将精氨酸、月桂醇酸钠、牙粉、谷氨酸钠、甘油、蒸馏水、和黄原胶加入搅拌机中进行第一次搅拌得到初步混合物,然后再往初步混合物中加入摩擦剂、调味剂和益生菌冻干粉,进行第二次搅拌,得到二次混合物。
研磨,真空脱气,得到牙膏膏体。可在真空制膏机中完成制备。
所述二次混合物还进行PH值调整,采用柠檬酸作为调节剂,将PH值调整为7。
实施例二
一种含精氨酸护龈牙膏,由以下按照重量份数计的原材料组成:
精氨酸20份,山梨糖醇2份,月桂醇酸钠2份,牙粉2份,益生菌冻干粉2份,谷氨酸钠0.01份,甘油8份,蒸馏水20份,黄原胶0.5份,二氧化硅10份。所述二氧化硅的粒径为0.5微米。
所述益生菌冻干粉的益生菌种类为唾液乳杆菌。
一种含精氨酸护龈牙膏的制备方法,包括以下步骤:
将精氨酸、月桂醇酸钠、牙粉、谷氨酸钠、甘油、蒸馏水、和黄原胶加入搅拌机中进行第一次搅拌得到初步混合物,然后再往初步混合物中加入摩擦剂、调味剂和益生菌冻干粉,进行第二次搅拌,得到二次混合物。
研磨,真空脱气,得到牙膏膏体。可在真空制膏机中完成制备。
所述二次混合物还进行PH值调整,采用柠檬酸作为调节剂,将PH值调整为6。
实施例三
一种含精氨酸护龈牙膏,由以下按照重量份数计的原材料组成:
精氨酸30份,薄荷醇8份,月桂醇酸钠3份,牙粉5份,益生菌冻干粉7份,谷氨酸钠0.05份,甘油10份,蒸馏水30份,黄原胶1.5份,摩擦剂15份。所述二氧化硅的粒径为30微米。
所述益生菌冻干粉的益生菌种类为唾液乳杆菌。
一种含精氨酸护龈牙膏的制备方法,包括以下步骤:
将精氨酸、月桂醇酸钠、牙粉、谷氨酸钠、甘油、蒸馏水、和黄原胶加入搅拌机中进行第一次搅拌得到初步混合物,然后再往初步混合物中加入摩擦剂、调味剂和益生菌冻干粉,进行第二次搅拌,得到二次混合物。
研磨,真空脱气,得到牙膏膏体。可在真空制膏机中完成制备。
所述二次混合物还进行PH值调整,采用氢氧化钠作为调节剂,将PH值调整为7。
需要说明的是,以上仅为本发明的优选实施例而已,并不用于限制本发明,尽管参照实施例对本发明进行了详细的说明,对于本领域的技术人员来说,其依然可以对前述实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换,但是凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。

Claims (8)

1.一种含精氨酸护龈牙膏,其特征在于,由以下按照重量份数计的原材料组成:
精氨酸20-30份,调味剂2-8份,月桂醇酸钠2份~3份,牙粉2份~5份,益生菌冻干粉2-7份,谷氨酸钠0.01-0.05份,甘油8-10份,蒸馏水20-30份,黄原胶0.5-1.5份,摩擦剂10-15份。
2.根据权利要求1所述的含精氨酸护龈牙膏,其特征在于,所述调味剂为山梨糖醇、甜菊糖苷和薄荷醇的一种或多种组合。
3.根据权利要求2所述的含精氨酸护龈牙膏,其特征在于,所述摩擦剂为二氧化硅。
4.根据权利要求3所述的含精氨酸护龈牙膏,其特征在于,所述二氧化硅的粒径为0.5-30微米。
5.根据权利要求4所述的含精氨酸护龈牙膏,其特征在于,所述益生菌冻干粉的益生菌种类为唾液乳杆菌。
6.一种根据权利要求1-5中任一项所述的含精氨酸护龈牙膏的制备方法,其特征在于,包括以下步骤:
将精氨酸、月桂醇酸钠、牙粉、谷氨酸钠、甘油、蒸馏水、和黄原胶加入搅拌机中进行第一次搅拌得到初步混合物,然后再往初步混合物中加入摩擦剂、调味剂和益生菌冻干粉,进行第二次搅拌,得到二次混合物;
研磨,真空脱气,得到牙膏膏体。
7.根据权利要求6所述的含精氨酸护龈牙膏的制备方法,其特征在于,所述二次混合物还进行PH值调整,将PH值调整为6-8。
8.根据权利要求7所述的含精氨酸护龈牙膏的制备方法,其特征在于,所述调节PH值采用柠檬酸或氢氧化钠作为调节剂。
CN202011522629.4A 2020-12-21 2020-12-21 一种含精氨酸护龈牙膏及其制备方法 Pending CN112274478A (zh)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150190329A1 (en) * 2012-08-20 2015-07-09 Obshchestvo S Ogranichennoj Otvetstvennostyu "Splat-Kosmetika" Mineral-enzyme complex for strengthening and whitening tooth enamel, oral hygiene composition, and toothpaste
CN105434322A (zh) * 2015-12-22 2016-03-30 南昌理工学院 一种含有口腔益生菌的牙膏
CN108324675A (zh) * 2018-04-04 2018-07-27 三椒口腔健康股份有限公司 一种含有副干酪乳杆菌的牙膏及其制备方法
CN108785119A (zh) * 2018-08-16 2018-11-13 江苏雪豹日化有限公司 一种氨基酸生物复合酶牙膏
CN110559233A (zh) * 2019-09-25 2019-12-13 曲沃李时珍医药科技有限公司 一种抗口腔幽门螺杆菌中药牙膏及其制备方法
CN111603407A (zh) * 2020-06-22 2020-09-01 江西草珊瑚口腔护理用品有限公司 一种含多种氨基酸的美白牙膏

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150190329A1 (en) * 2012-08-20 2015-07-09 Obshchestvo S Ogranichennoj Otvetstvennostyu "Splat-Kosmetika" Mineral-enzyme complex for strengthening and whitening tooth enamel, oral hygiene composition, and toothpaste
CN105434322A (zh) * 2015-12-22 2016-03-30 南昌理工学院 一种含有口腔益生菌的牙膏
CN108324675A (zh) * 2018-04-04 2018-07-27 三椒口腔健康股份有限公司 一种含有副干酪乳杆菌的牙膏及其制备方法
CN108785119A (zh) * 2018-08-16 2018-11-13 江苏雪豹日化有限公司 一种氨基酸生物复合酶牙膏
CN110559233A (zh) * 2019-09-25 2019-12-13 曲沃李时珍医药科技有限公司 一种抗口腔幽门螺杆菌中药牙膏及其制备方法
CN111603407A (zh) * 2020-06-22 2020-09-01 江西草珊瑚口腔护理用品有限公司 一种含多种氨基酸的美白牙膏

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