CA2880708C - Plant extracts for improving cognitive health and function - Google Patents

Plant extracts for improving cognitive health and function Download PDF

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Publication number
CA2880708C
CA2880708C CA2880708A CA2880708A CA2880708C CA 2880708 C CA2880708 C CA 2880708C CA 2880708 A CA2880708 A CA 2880708A CA 2880708 A CA2880708 A CA 2880708A CA 2880708 C CA2880708 C CA 2880708C
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Canada
Prior art keywords
memory
cognitive
mice
samp8
extract
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CA2880708A
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English (en)
French (fr)
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CA2880708A1 (en
Inventor
Michael Ceddia
Kelli HERRLINGER
Brandon LEWIS
Harry FENG
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Kemin Industries Inc
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Kemin Industries Inc
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Publication of CA2880708A1 publication Critical patent/CA2880708A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
CA2880708A 2012-08-09 2013-08-09 Plant extracts for improving cognitive health and function Active CA2880708C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261681414P 2012-08-09 2012-08-09
US61/681,414 2012-08-09
PCT/US2013/054274 WO2014026081A1 (en) 2012-08-09 2013-08-09 Plant extracts for improving cognitive health and function

Publications (2)

Publication Number Publication Date
CA2880708A1 CA2880708A1 (en) 2014-02-13
CA2880708C true CA2880708C (en) 2023-09-26

Family

ID=50066333

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2880708A Active CA2880708C (en) 2012-08-09 2013-08-09 Plant extracts for improving cognitive health and function

Country Status (11)

Country Link
US (2) US20140044813A1 (https=)
EP (1) EP2882443B1 (https=)
JP (4) JP2015524484A (https=)
KR (1) KR101947352B1 (https=)
CN (2) CN104684562A (https=)
AU (1) AU2013299491B2 (https=)
BR (1) BR112015002739A2 (https=)
CA (1) CA2880708C (https=)
ES (1) ES2715005T3 (https=)
PL (1) PL2882443T3 (https=)
WO (1) WO2014026081A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140044813A1 (en) * 2012-08-09 2014-02-13 Kemin Industries, Inc. Plant Extracts for Improving Cognitive Health and Function
JP2017507125A (ja) * 2014-01-30 2017-03-16 ケミン、インダストリーズ、インコーポレーテッドKemin Industries, Inc. 認知機能を向上させるための植物抽出物
JP2017527591A (ja) * 2014-09-15 2017-09-21 ケミン、インダストリーズ、インコーポレーテッドKemin Industries, Inc. 認知機能向上のための植物抽出物
MX2017004582A (es) * 2014-10-08 2017-10-12 Abbott Lab Composiciones nutricionales que comprenden un componente oxidable y un extracto de plantas solubles en agua.
EP3538085B1 (en) * 2016-11-11 2023-07-12 Kemin Industries, Inc. Use of a spearmint extract for improving the rate of neurogenesis
CN106727915B (zh) * 2017-01-18 2020-03-31 云南德彩堂生物医药科技有限公司 一种稳定高效提高记忆的组合物及其制备方法和应用
EP3703675A4 (en) * 2017-10-30 2021-06-16 Neuropore Therapies, Inc. SUBSTITUTED PHENYLSULFONYLPHÉNYLTRIAZOLETHIONES AND ASSOCIATED USES
CN109602759B (zh) * 2019-01-17 2020-10-09 广西医科大学 罗汉松实多糖的用途
KR102421772B1 (ko) * 2019-05-21 2022-07-18 건국대학교 글로컬산학협력단 클로로필 및 로즈마린산을 포함하는 미세먼지에 의해 유발된 신경염증 또는 신경 퇴행성 질환의 예방 또는 치료용 조성물
CN110463846A (zh) * 2019-07-30 2019-11-19 河南科技学院 留兰香提取物在制备抗宠物衰老药物或宠物食品中的应用
JP7330630B2 (ja) * 2019-11-20 2023-08-22 株式会社ニップン ロスマリン酸及びカルノシン酸を有効成分とする神経突起伸長誘導作用を有する組成物
JP2022104122A (ja) * 2020-12-28 2022-07-08 株式会社ニップン オキシトシン関連シグナル活性化剤
JP2026503187A (ja) * 2022-10-27 2026-01-28 ケミン、インダストリーズ、インコーポレーテッド 網膜神経栄養のためのスペアミント抽出物の使用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999059606A1 (en) * 1998-05-16 1999-11-25 Mogam Biotechnology Research Institute Use of rosmarinic acid and derivatives thereof as an immunosuppressant or an inhibitor of sh2-mediated process
JP4629822B2 (ja) * 1999-12-02 2011-02-09 長瀬産業株式会社 神経成長因子合成促進剤
JP2006199666A (ja) * 2005-01-24 2006-08-03 Nagase & Co Ltd 健忘症の予防・治療剤
EP1940389A2 (en) * 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
EP1930019A1 (en) * 2006-11-24 2008-06-11 DSMIP Assets B.V. Rosemary extracts, dietary and pharmaceutical compositions containing them and their uses
EP1925213A1 (en) * 2006-11-24 2008-05-28 DSMIP Assets B.V. Dietary and pharmaceutical compositions comprising a sage extract comprising a mixture of tricyclic diterpenes and their derivatives and their uses
US20100137433A1 (en) * 2007-01-24 2010-06-03 Laima Kott Production of Rosmarinic Acid from Spearmint and uses Thereof
US7972633B2 (en) * 2007-02-07 2011-07-05 Applied Cognitive Sciences, LLC Nutritional supplements for healthy memory and mental function
ES2561330T3 (es) * 2007-10-17 2016-02-25 Rudolf Wild Gmbh & Co. Kg Composición que comprende extractos de toronjil
AU2010258356B2 (en) * 2009-06-12 2017-01-19 Generex Pharmaceuticals, Inc. Compositions and methods for prevention and treatment of brain diseases and conditions
CN101773488A (zh) * 2010-02-10 2010-07-14 青岛大学 一种基于迷迭香酸的药物及其在治疗帕金森病中的应用
JP2011256118A (ja) * 2010-06-07 2011-12-22 Kao Corp Il−8及びgm−csf発現抑制剤
US20140044813A1 (en) * 2012-08-09 2014-02-13 Kemin Industries, Inc. Plant Extracts for Improving Cognitive Health and Function

Also Published As

Publication number Publication date
WO2014026081A1 (en) 2014-02-13
KR101947352B1 (ko) 2019-02-12
CA2880708A1 (en) 2014-02-13
KR20150041654A (ko) 2015-04-16
EP2882443B1 (en) 2019-01-16
AU2013299491B2 (en) 2018-03-15
US20250009703A1 (en) 2025-01-09
US20140044813A1 (en) 2014-02-13
EP2882443A4 (en) 2016-01-06
JP2023027232A (ja) 2023-03-01
JP2015524484A (ja) 2015-08-24
JP2021066735A (ja) 2021-04-30
AU2013299491A1 (en) 2015-02-12
JP2025029029A (ja) 2025-03-05
ES2715005T3 (es) 2019-05-31
BR112015002739A2 (pt) 2017-07-04
CN104684562A (zh) 2015-06-03
PL2882443T3 (pl) 2019-06-28
EP2882443A1 (en) 2015-06-17
CN111358832A (zh) 2020-07-03

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Effective date: 20180216