CA2879228C - Attenuated swine influenza vaccines and methods of making and use thereof - Google Patents
Attenuated swine influenza vaccines and methods of making and use thereof Download PDFInfo
- Publication number
- CA2879228C CA2879228C CA2879228A CA2879228A CA2879228C CA 2879228 C CA2879228 C CA 2879228C CA 2879228 A CA2879228 A CA 2879228A CA 2879228 A CA2879228 A CA 2879228A CA 2879228 C CA2879228 C CA 2879228C
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- CA
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- Prior art keywords
- influenza
- seq
- sequence
- strain
- attenuated
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16161—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261672398P | 2012-07-17 | 2012-07-17 | |
| US61/672,398 | 2012-07-17 | ||
| PCT/US2013/050000 WO2014014726A1 (en) | 2012-07-17 | 2013-07-11 | Attenuated swine influenza vaccines and methods of making and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2879228A1 CA2879228A1 (en) | 2014-01-23 |
| CA2879228C true CA2879228C (en) | 2021-07-13 |
Family
ID=48874529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2879228A Active CA2879228C (en) | 2012-07-17 | 2013-07-11 | Attenuated swine influenza vaccines and methods of making and use thereof |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US9216211B2 (https=) |
| EP (1) | EP2874656B1 (https=) |
| JP (1) | JP6467672B2 (https=) |
| KR (1) | KR102027758B1 (https=) |
| CN (1) | CN104582725B (https=) |
| AU (2) | AU2013290597B2 (https=) |
| BR (1) | BR112015001020B1 (https=) |
| CA (1) | CA2879228C (https=) |
| DK (1) | DK2874656T3 (https=) |
| EA (1) | EA033027B1 (https=) |
| ES (1) | ES2662022T3 (https=) |
| HU (1) | HUE036110T2 (https=) |
| MX (1) | MX365880B (https=) |
| MY (1) | MY166879A (https=) |
| NZ (2) | NZ712713A (https=) |
| PH (1) | PH12015500095A1 (https=) |
| PL (1) | PL2874656T3 (https=) |
| PT (1) | PT2874656T (https=) |
| WO (1) | WO2014014726A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2874656T3 (pl) * | 2012-07-17 | 2018-04-30 | Merial, Inc. | Atenuowane szczepionki przeciw grypie świń oraz ich sposoby wytwarzania i zastosowanie |
| JP6839714B2 (ja) * | 2015-12-28 | 2021-03-10 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | Ｍ Ｈｙｏ多重ワクチン及びその使用 |
| EA201991319A1 (ru) * | 2016-11-30 | 2019-11-29 | Вакцины аттенуированного свиного гриппа и способы их изготовления и применения | |
| CN106939355A (zh) * | 2017-03-01 | 2017-07-11 | 苏州系统医学研究所 | 一种流感病毒弱毒活疫苗毒株的筛选和鉴定方法 |
| CN107064499B (zh) * | 2017-03-15 | 2019-06-18 | 青岛蔚蓝生物制品有限公司 | 禽流感病毒np蛋白抗原表位多肽及其胶体金试纸盒 |
| JP2021508696A (ja) | 2017-12-22 | 2021-03-11 | コーダ−ジェニックス・インコーポレイテッドＣｏｄａ−Ｇｅｎｉｘ， Ｉｎｃ． | がん処置のためのコドン対脱最適化領域を有する組換え型ウイルス及びその使用法 |
| CN112040977A (zh) | 2018-03-08 | 2020-12-04 | 科达金尼克斯有限公司 | 减毒黄病毒 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4708871A (en) | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| US5585250A (en) | 1993-08-20 | 1996-12-17 | The United States Of America As Represented By The Department Of Health & Human Services | Dampening of an immunodominant epitope of an antigen for use in plant, animal and human compositions and immunotherapies |
| ES2241042T3 (es) | 1996-10-11 | 2005-10-16 | The Regents Of The University Of California | Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora. |
| US5980912A (en) | 1997-03-25 | 1999-11-09 | Zonagen, Inc. | Chitosan induced immunopotentiation |
| KR20060026854A (ko) | 2003-05-28 | 2006-03-24 | 위스콘신 얼럼나이 리서어치 화운데이션 | ＰｏｌⅡ 프로모터 및 리보자임을 갖는 재조합 인플루엔자벡터 |
| US7871626B2 (en) * | 2005-08-04 | 2011-01-18 | St. Jude Children's Research Hospital | Modified influenza virus for monitoring and improving vaccine efficiency |
| CA2690196A1 (en) * | 2007-06-18 | 2008-12-24 | Medimmune, Llc | Influenza b viruses having alterations in the hemaglutinin polypeptide |
| CA2716340A1 (en) | 2008-02-21 | 2009-08-27 | Biological Mimetics, Inc. | Immunogenic influenza composition |
| CN102985107A (zh) | 2010-01-24 | 2013-03-20 | 生物模仿公司 | 免疫性流感成分 |
| PL2874656T3 (pl) * | 2012-07-17 | 2018-04-30 | Merial, Inc. | Atenuowane szczepionki przeciw grypie świń oraz ich sposoby wytwarzania i zastosowanie |
-
2013
- 2013-07-11 PL PL13740452T patent/PL2874656T3/pl unknown
- 2013-07-11 KR KR1020157004138A patent/KR102027758B1/ko active Active
- 2013-07-11 NZ NZ712713A patent/NZ712713A/en unknown
- 2013-07-11 EA EA201500140A patent/EA033027B1/ru not_active IP Right Cessation
- 2013-07-11 CA CA2879228A patent/CA2879228C/en active Active
- 2013-07-11 PT PT137404521T patent/PT2874656T/pt unknown
- 2013-07-11 ES ES13740452.1T patent/ES2662022T3/es active Active
- 2013-07-11 MX MX2015000713A patent/MX365880B/es active IP Right Grant
- 2013-07-11 AU AU2013290597A patent/AU2013290597B2/en active Active
- 2013-07-11 DK DK13740452.1T patent/DK2874656T3/en active
- 2013-07-11 MY MYPI2015000100A patent/MY166879A/en unknown
- 2013-07-11 WO PCT/US2013/050000 patent/WO2014014726A1/en not_active Ceased
- 2013-07-11 BR BR112015001020-2A patent/BR112015001020B1/pt active IP Right Grant
- 2013-07-11 US US13/939,321 patent/US9216211B2/en active Active
- 2013-07-11 EP EP13740452.1A patent/EP2874656B1/en active Active
- 2013-07-11 CN CN201380043383.4A patent/CN104582725B/zh active Active
- 2013-07-11 NZ NZ704188A patent/NZ704188A/en unknown
- 2013-07-11 HU HUE13740452A patent/HUE036110T2/hu unknown
- 2013-07-11 JP JP2015523130A patent/JP6467672B2/ja active Active
-
2015
- 2015-01-14 PH PH12015500095A patent/PH12015500095A1/en unknown
- 2015-12-21 US US14/977,485 patent/US9623105B2/en active Active
-
2016
- 2016-04-27 AU AU2016202693A patent/AU2016202693B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20180711 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 12TH ANNIV.) - STANDARD Year of fee payment: 12 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250701 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250701 |