EA033027B1 - Ослабленные вакцины от свиного гриппа и способы их получения и применения - Google Patents
Ослабленные вакцины от свиного гриппа и способы их получения и примененияInfo
- Publication number
- EA033027B1 EA033027B1 EA201500140A EA201500140A EA033027B1 EA 033027 B1 EA033027 B1 EA 033027B1 EA 201500140 A EA201500140 A EA 201500140A EA 201500140 A EA201500140 A EA 201500140A EA 033027 B1 EA033027 B1 EA 033027B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- attenuated
- methods
- influenza
- making
- strains
- Prior art date
Links
- 230000002238 attenuated effect Effects 0.000 title abstract 4
- 206010069767 H1N1 influenza Diseases 0.000 title abstract 2
- 208000009620 Orthomyxoviridae Infections Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 201000010740 swine influenza Diseases 0.000 title abstract 2
- 229960003971 influenza vaccine Drugs 0.000 title 1
- 206010022000 influenza Diseases 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 241000282898 Sus scrofa Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16161—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261672398P | 2012-07-17 | 2012-07-17 | |
| PCT/US2013/050000 WO2014014726A1 (en) | 2012-07-17 | 2013-07-11 | Attenuated swine influenza vaccines and methods of making and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201500140A1 EA201500140A1 (ru) | 2016-02-29 |
| EA033027B1 true EA033027B1 (ru) | 2019-08-30 |
Family
ID=48874529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201500140A EA033027B1 (ru) | 2012-07-17 | 2013-07-11 | Ослабленные вакцины от свиного гриппа и способы их получения и применения |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US9216211B2 (https=) |
| EP (1) | EP2874656B1 (https=) |
| JP (1) | JP6467672B2 (https=) |
| KR (1) | KR102027758B1 (https=) |
| CN (1) | CN104582725B (https=) |
| AU (2) | AU2013290597B2 (https=) |
| BR (1) | BR112015001020B1 (https=) |
| CA (1) | CA2879228C (https=) |
| DK (1) | DK2874656T3 (https=) |
| EA (1) | EA033027B1 (https=) |
| ES (1) | ES2662022T3 (https=) |
| HU (1) | HUE036110T2 (https=) |
| MX (1) | MX365880B (https=) |
| MY (1) | MY166879A (https=) |
| NZ (2) | NZ712713A (https=) |
| PH (1) | PH12015500095A1 (https=) |
| PL (1) | PL2874656T3 (https=) |
| PT (1) | PT2874656T (https=) |
| WO (1) | WO2014014726A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2874656T3 (pl) * | 2012-07-17 | 2018-04-30 | Merial, Inc. | Atenuowane szczepionki przeciw grypie świń oraz ich sposoby wytwarzania i zastosowanie |
| JP6839714B2 (ja) * | 2015-12-28 | 2021-03-10 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | Ｍ Ｈｙｏ多重ワクチン及びその使用 |
| EA201991319A1 (ru) * | 2016-11-30 | 2019-11-29 | Вакцины аттенуированного свиного гриппа и способы их изготовления и применения | |
| CN106939355A (zh) * | 2017-03-01 | 2017-07-11 | 苏州系统医学研究所 | 一种流感病毒弱毒活疫苗毒株的筛选和鉴定方法 |
| CN107064499B (zh) * | 2017-03-15 | 2019-06-18 | 青岛蔚蓝生物制品有限公司 | 禽流感病毒np蛋白抗原表位多肽及其胶体金试纸盒 |
| JP2021508696A (ja) | 2017-12-22 | 2021-03-11 | コーダ−ジェニックス・インコーポレイテッドＣｏｄａ−Ｇｅｎｉｘ， Ｉｎｃ． | がん処置のためのコドン対脱最適化領域を有する組換え型ウイルス及びその使用法 |
| CN112040977A (zh) | 2018-03-08 | 2020-12-04 | 科达金尼克斯有限公司 | 减毒黄病毒 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011091376A2 (en) * | 2010-01-24 | 2011-07-28 | Biological Mimetics, Inc. | Immunogenic influenza composition |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4708871A (en) | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| US5585250A (en) | 1993-08-20 | 1996-12-17 | The United States Of America As Represented By The Department Of Health & Human Services | Dampening of an immunodominant epitope of an antigen for use in plant, animal and human compositions and immunotherapies |
| ES2241042T3 (es) | 1996-10-11 | 2005-10-16 | The Regents Of The University Of California | Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora. |
| US5980912A (en) | 1997-03-25 | 1999-11-09 | Zonagen, Inc. | Chitosan induced immunopotentiation |
| KR20060026854A (ko) | 2003-05-28 | 2006-03-24 | 위스콘신 얼럼나이 리서어치 화운데이션 | ＰｏｌⅡ 프로모터 및 리보자임을 갖는 재조합 인플루엔자벡터 |
| US7871626B2 (en) * | 2005-08-04 | 2011-01-18 | St. Jude Children's Research Hospital | Modified influenza virus for monitoring and improving vaccine efficiency |
| CA2690196A1 (en) * | 2007-06-18 | 2008-12-24 | Medimmune, Llc | Influenza b viruses having alterations in the hemaglutinin polypeptide |
| CA2716340A1 (en) | 2008-02-21 | 2009-08-27 | Biological Mimetics, Inc. | Immunogenic influenza composition |
| PL2874656T3 (pl) * | 2012-07-17 | 2018-04-30 | Merial, Inc. | Atenuowane szczepionki przeciw grypie świń oraz ich sposoby wytwarzania i zastosowanie |
-
2013
- 2013-07-11 PL PL13740452T patent/PL2874656T3/pl unknown
- 2013-07-11 KR KR1020157004138A patent/KR102027758B1/ko active Active
- 2013-07-11 NZ NZ712713A patent/NZ712713A/en unknown
- 2013-07-11 EA EA201500140A patent/EA033027B1/ru not_active IP Right Cessation
- 2013-07-11 CA CA2879228A patent/CA2879228C/en active Active
- 2013-07-11 PT PT137404521T patent/PT2874656T/pt unknown
- 2013-07-11 ES ES13740452.1T patent/ES2662022T3/es active Active
- 2013-07-11 MX MX2015000713A patent/MX365880B/es active IP Right Grant
- 2013-07-11 AU AU2013290597A patent/AU2013290597B2/en active Active
- 2013-07-11 DK DK13740452.1T patent/DK2874656T3/en active
- 2013-07-11 MY MYPI2015000100A patent/MY166879A/en unknown
- 2013-07-11 WO PCT/US2013/050000 patent/WO2014014726A1/en not_active Ceased
- 2013-07-11 BR BR112015001020-2A patent/BR112015001020B1/pt active IP Right Grant
- 2013-07-11 US US13/939,321 patent/US9216211B2/en active Active
- 2013-07-11 EP EP13740452.1A patent/EP2874656B1/en active Active
- 2013-07-11 CN CN201380043383.4A patent/CN104582725B/zh active Active
- 2013-07-11 NZ NZ704188A patent/NZ704188A/en unknown
- 2013-07-11 HU HUE13740452A patent/HUE036110T2/hu unknown
- 2013-07-11 JP JP2015523130A patent/JP6467672B2/ja active Active
-
2015
- 2015-01-14 PH PH12015500095A patent/PH12015500095A1/en unknown
- 2015-12-21 US US14/977,485 patent/US9623105B2/en active Active
-
2016
- 2016-04-27 AU AU2016202693A patent/AU2016202693B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011091376A2 (en) * | 2010-01-24 | 2011-07-28 | Biological Mimetics, Inc. | Immunogenic influenza composition |
Non-Patent Citations (2)
| Title |
|---|
| ABE Y, TAKASHITA E, SUGAWARA K, MATSUZAKI Y, MURAKI Y, HONGO S.: "Effect of the addition of oligosaccharides on the biological activities and antigenicity of influenza A/H3N2 virus hemagglutinin.", JOURNAL OF VIROLOGY., THE AMERICAN SOCIETY FOR MICROBIOLOGY., US, vol. 78, no. 18, 1 September 2004 (2004-09-01), US, pages 9605 - 9611, XP002717640, ISSN: 0022-538X, DOI: 10.1128/JVI.78.18.9605-9611.2004 * |
| VINCENT, A.L. MA, W. LAGER, K.M. JANKE, B.H. WEBBY, R.J. GARCIA-SASTRE, A. RICHT, J.A.: "Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine", VACCINE, ELSEVIER, AMSTERDAM, NL, vol. 25, no. 47, 26 October 2007 (2007-10-26), AMSTERDAM, NL, pages 7999 - 8009, XP022317477, ISSN: 0264-410X, DOI: 10.1016/j.vaccine.2007.09.019 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM |