CA2870198C - Process for purifying recombinant plasmodium falciparum circumsporozoite protein - Google Patents

Process for purifying recombinant plasmodium falciparum circumsporozoite protein Download PDF

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Publication number
CA2870198C
CA2870198C CA2870198A CA2870198A CA2870198C CA 2870198 C CA2870198 C CA 2870198C CA 2870198 A CA2870198 A CA 2870198A CA 2870198 A CA2870198 A CA 2870198A CA 2870198 C CA2870198 C CA 2870198C
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CA
Canada
Prior art keywords
rcsp
days
circumsporozoite protein
falciparum circumsporozoite
arginine
Prior art date
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Active
Application number
CA2870198A
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English (en)
French (fr)
Other versions
CA2870198A1 (en
Inventor
Jeffrey Allen
Greg CANTIN
Ryan HAVERSTOCK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pelican Technology Holdings Inc
Original Assignee
Pfenex Inc
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Application filed by Pfenex Inc filed Critical Pfenex Inc
Publication of CA2870198A1 publication Critical patent/CA2870198A1/en
Application granted granted Critical
Publication of CA2870198C publication Critical patent/CA2870198C/en
Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2870198A 2012-05-01 2013-04-22 Process for purifying recombinant plasmodium falciparum circumsporozoite protein Active CA2870198C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261641105P 2012-05-01 2012-05-01
US61/641,105 2012-05-01
US13/844,261 US9169304B2 (en) 2012-05-01 2013-03-15 Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
US13/844,261 2013-03-15
PCT/US2013/037656 WO2013165732A1 (en) 2012-05-01 2013-04-22 Process for purifying recombinant plasmodium falciparum circumsporozoite protein

Publications (2)

Publication Number Publication Date
CA2870198A1 CA2870198A1 (en) 2013-11-07
CA2870198C true CA2870198C (en) 2019-12-03

Family

ID=49514758

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2870198A Active CA2870198C (en) 2012-05-01 2013-04-22 Process for purifying recombinant plasmodium falciparum circumsporozoite protein

Country Status (16)

Country Link
US (2) US9169304B2 (enExample)
EP (1) EP2844666B1 (enExample)
JP (1) JP6238967B2 (enExample)
KR (1) KR102087461B1 (enExample)
CN (1) CN104379596B (enExample)
AR (1) AR090900A1 (enExample)
AU (1) AU2013256757B2 (enExample)
BR (1) BR112014027019B1 (enExample)
CA (1) CA2870198C (enExample)
MX (1) MX352093B (enExample)
MY (1) MY166380A (enExample)
NZ (1) NZ630121A (enExample)
SG (1) SG11201407108TA (enExample)
TW (1) TWI630213B (enExample)
WO (1) WO2013165732A1 (enExample)
ZA (1) ZA201407420B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
EP3092002B1 (en) * 2014-01-09 2019-09-25 Kentucky Bioprocessing, Inc. Method of purifying monoclonal antibodies
JP2017512477A (ja) * 2014-03-28 2017-05-25 コンジュゴン，インコーポレーテッド 治療細菌の小型コロニー変種の調製
WO2016089782A1 (en) 2014-12-01 2016-06-09 Pfenex Inc. Fusion partners for peptide production
CN109966319B (zh) * 2017-12-22 2022-11-22 四川好医生攀西药业有限责任公司 一种康复新液的原料及其制备方法和应用
CN108559721A (zh) * 2018-05-15 2018-09-21 北京师范大学 一种净化空气的复合微生物菌剂及其应用
CN116457012A (zh) * 2020-06-29 2023-07-18 帕斯公司 红细胞前期疟疾疫苗
CN114763542A (zh) * 2021-01-12 2022-07-19 正大天晴药业集团股份有限公司 利用酵母胞内表达制备黄曲霉尿酸氧化酶的方法

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Also Published As

Publication number Publication date
KR102087461B1 (ko) 2020-03-10
JP6238967B2 (ja) 2017-11-29
ZA201407420B (en) 2016-10-26
MX2014013124A (es) 2015-02-05
MX352093B (es) 2017-11-08
US20140051841A1 (en) 2014-02-20
MY166380A (en) 2018-06-25
CN104379596B (zh) 2018-05-29
AR090900A1 (es) 2014-12-17
NZ630121A (en) 2016-06-24
EP2844666A4 (en) 2015-11-04
US9169304B2 (en) 2015-10-27
US9849177B2 (en) 2017-12-26
EP2844666A1 (en) 2015-03-11
SG11201407108TA (en) 2014-11-27
US20160051677A1 (en) 2016-02-25
KR20150027743A (ko) 2015-03-12
AU2013256757A1 (en) 2014-10-30
BR112014027019B1 (pt) 2022-09-06
CN104379596A (zh) 2015-02-25
CA2870198A1 (en) 2013-11-07
JP2015517464A (ja) 2015-06-22
TW201348250A (zh) 2013-12-01
TWI630213B (zh) 2018-07-21
AU2013256757B2 (en) 2017-02-16
WO2013165732A1 (en) 2013-11-07
EP2844666B1 (en) 2019-07-17
BR112014027019A2 (pt) 2017-07-11

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