CA2857506C - Accurate dose control mechanisms and drug delivery syringes - Google Patents

Accurate dose control mechanisms and drug delivery syringes Download PDF

Info

Publication number
CA2857506C
CA2857506C CA2857506A CA2857506A CA2857506C CA 2857506 C CA2857506 C CA 2857506C CA 2857506 A CA2857506 A CA 2857506A CA 2857506 A CA2857506 A CA 2857506A CA 2857506 C CA2857506 C CA 2857506C
Authority
CA
Canada
Prior art keywords
plunger
screw
syringe
housing
pitch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2857506A
Other languages
English (en)
French (fr)
Other versions
CA2857506A1 (en
Inventor
Gautam N. Shetty
Lou Castagna
Original Assignee
Unitract Syringe Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unitract Syringe Pty Ltd filed Critical Unitract Syringe Pty Ltd
Publication of CA2857506A1 publication Critical patent/CA2857506A1/en
Application granted granted Critical
Publication of CA2857506C publication Critical patent/CA2857506C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31526—Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/041—Controlled or regulated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CA2857506A 2011-12-08 2012-12-06 Accurate dose control mechanisms and drug delivery syringes Expired - Fee Related CA2857506C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161568509P 2011-12-08 2011-12-08
US61/568,509 2011-12-08
PCT/US2012/068210 WO2013086167A1 (en) 2011-12-08 2012-12-06 Accurate dose control mechanisms and drug delivery syringes

Publications (2)

Publication Number Publication Date
CA2857506A1 CA2857506A1 (en) 2013-06-13
CA2857506C true CA2857506C (en) 2020-01-14

Family

ID=47472025

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2857506A Expired - Fee Related CA2857506C (en) 2011-12-08 2012-12-06 Accurate dose control mechanisms and drug delivery syringes

Country Status (17)

Country Link
US (1) US9345839B2 (enExample)
EP (1) EP2788054B1 (enExample)
JP (2) JP6298946B2 (enExample)
KR (1) KR20140105457A (enExample)
CN (1) CN103998080B (enExample)
AU (1) AU2012347818B2 (enExample)
BR (1) BR112014013632A8 (enExample)
CA (1) CA2857506C (enExample)
DK (1) DK2788054T3 (enExample)
IL (1) IL232733B (enExample)
IN (1) IN2014CN04000A (enExample)
MX (1) MX351572B (enExample)
PT (1) PT2788054T (enExample)
RU (1) RU2650207C2 (enExample)
TW (1) TWI555544B (enExample)
WO (1) WO2013086167A1 (enExample)
ZA (1) ZA201404088B (enExample)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
EP2627292B1 (en) 2010-10-15 2018-10-10 Clearside Biomedical, Inc. Device for ocular access
WO2017204787A1 (en) * 2011-12-08 2017-11-30 Unitract Syringe Pty Ltd Accurate dose control mechanisms and drug delivery syringes
RU2650207C2 (ru) * 2011-12-08 2018-04-11 Юнитрект Сириндж Пти Лтд Механизм контроля точной величины дозы и шприц для доставки лекарства
KR102467714B1 (ko) 2012-11-08 2022-11-16 클리어사이드 바이오메디컬, 인코포레이드 인간 대상체에서 안구 질병을 치료하기 위한 방법 및 장치
AU2014259694B2 (en) 2013-05-03 2018-11-08 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
US10188550B2 (en) 2013-06-03 2019-01-29 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
US9586008B2 (en) * 2013-07-16 2017-03-07 Unitract Syringe Pty Ltd Syringes for sequential delivery of injectables
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
KR101472821B1 (ko) * 2014-05-14 2014-12-16 김준우 성분 분리기
WO2015196085A2 (en) 2014-06-20 2015-12-23 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
US10049189B2 (en) * 2014-09-29 2018-08-14 Min Wei Method for developing parenteral therapeutic product with drug delivery device through clinical trial
USD750223S1 (en) 2014-10-14 2016-02-23 Clearside Biomedical, Inc. Medical injector for ocular injection
JP6471029B2 (ja) * 2015-04-10 2019-02-13 株式会社ダイセル 注射器
AU2016291849B2 (en) 2015-07-12 2021-09-23 Patients Pending Ltd. Cover for liquid delivery system with integrated plunger position sensing, and corresponding method
EP3187213A1 (en) * 2015-12-29 2017-07-05 Galderma S.A. Syringe with click mechanism
WO2017139375A1 (en) 2016-02-10 2017-08-17 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
CN109069753A (zh) * 2016-02-25 2018-12-21 中央研究院 用于搅拌及递送包含细胞的组成物的注射装置
US20190298490A1 (en) * 2016-04-13 2019-10-03 3M Innovative Properties Company A syringe for dispensing a dental substance
EP3442623B1 (en) * 2016-04-15 2021-01-20 Santen Pharmaceutical Co., Ltd. Accurate, precise microliter dosing syringe
WO2017192565A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
BR112018074108A2 (pt) * 2016-05-24 2019-03-06 Unl Holdings Llc seringas de administração de medicamentos e mecanismos de controle de dose exata
WO2017219018A2 (en) * 2016-06-17 2017-12-21 Becton, Dickinson And Company Method and apparatus for wetting internal fluid path surfaces of a fluid port to increase ultrasonic signal transmission
CN106038053B (zh) * 2016-07-05 2018-11-20 颜繁诚 眼球后注药装置
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
US11083851B2 (en) 2016-09-17 2021-08-10 Ethan Pedde Methods, systems and devices for administering medication
US12090294B2 (en) 2017-05-02 2024-09-17 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
EP3638346B1 (en) * 2017-06-16 2025-10-15 Credence Medsystems, Inc. System and method for safety syringe
DE102017005779A1 (de) 2017-06-19 2018-12-20 Giesecke+Devrient Mobile Security Gmbh Mikrooptisches Element mit Farbwechsel
FR3072297B1 (fr) * 2017-10-17 2023-05-12 Edix Sa Dispositif d'injection manuelle
IL310302B2 (en) 2017-12-13 2025-06-01 Regeneron Pharma Devices and methods for precision dose delivery
RU2710348C1 (ru) * 2019-03-11 2019-12-25 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ярославский государственный медицинский университет" Министерства здравоохранения Российской Федерации Универсальный одноразовый шприц
US20220168510A1 (en) * 2019-04-09 2022-06-02 Congruence Medical Solutions, Llc Injection Device
MA54325A (fr) 2019-06-05 2022-05-11 Regeneron Pharma Dispositifs et procédés pour l'administration précise de doses
IL267610A (en) * 2019-06-24 2019-10-31 Dali Medical Devices Ltd dose monitoring
CN115038480B (zh) * 2019-11-14 2025-01-10 和谐医疗解决方案有限责任公司 可变剂量注射筒
JP2020121157A (ja) * 2020-04-10 2020-08-13 ユーエヌエル ホールディングス エルエルシーＵＮＬ Ｈｏｌｄｉｎｇｓ ＬＬＣ 正確な投与量制御機構および薬物送達注射器
CN111529826B (zh) * 2020-05-28 2025-06-20 南京康友医疗科技有限公司 一种注射装置
US11883635B2 (en) 2020-06-17 2024-01-30 Credence MedSystems System and method for microdose injection
CN115715209B (zh) * 2020-08-20 2026-04-07 泰尔茂株式会社 预灌装注射器
US20220280389A1 (en) * 2021-03-06 2022-09-08 Control, Ltd. Syringe Assembly & Method for Accurate Dosing
CN113578697B (zh) * 2021-07-23 2023-07-28 信利光电股份有限公司 一种点导电银浆用注射器
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
WO2024180081A1 (en) * 2023-02-28 2024-09-06 Dunne, Stephen Terence Controlled dose syringe
WO2025154005A1 (en) * 2024-01-19 2025-07-24 Gupta Nalini K An aseptic syringe for collection of samples
WO2025199106A1 (en) * 2024-03-19 2025-09-25 Halozyme, Inc. Autoinjector

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2943624A (en) 1958-04-17 1960-07-05 Mavis M Alquist Quantitative indicator for syringes
US3596659A (en) * 1968-12-09 1971-08-03 Nuclear Associates Inc A shielding holder for a syringe
US4018223A (en) 1974-12-09 1977-04-19 Andros Incorporated Dosage control device
US4444335A (en) 1981-09-14 1984-04-24 Merck & Co., Inc. Delivery of adjustable quantities of materials
US4465478A (en) 1982-10-14 1984-08-14 Collagen Corporation Syringe force amplification device
GB2140302A (en) 1983-05-26 1984-11-28 Microsurgical Equipment Ltd An aspiration adaptor for a syringe
FR2583291A1 (fr) 1985-06-14 1986-12-19 Hazon Bernard Dispositif d'avancement pas a pas du piston de seringues par double vis coaxiale avec controle du debit d'injection. application aux injections medicamenteuses intra-dermiques repetitives
US4687472A (en) 1986-11-12 1987-08-18 Gross Daniel A Injection assisting apparatus
GB8713810D0 (en) 1987-06-12 1987-07-15 Hypoguard Uk Ltd Measured dose dispensing device
WO1989004187A2 (en) * 1987-11-06 1989-05-18 Louis Paul Ellgass Non-reusable syringe
US5135511A (en) 1990-08-22 1992-08-04 Becton, Dickinson And Company Assembly for aspirating tissue, including adapter for syringe
US5115816A (en) 1991-01-24 1992-05-26 Peter F. Lee, Inc. Single-hand controlled fine needle aspiration device
AR243387A1 (es) 1991-10-03 1993-08-31 Cesar Gabriel Corsich Jeringa hipodermica con embolo trabable para evitar su recarga y reutilizacion.
US5378233A (en) 1992-11-18 1995-01-03 Habley Medical Technology Corporation Selected dose pharmaceutical dispenser
US5346475A (en) 1993-10-27 1994-09-13 Edward Gregorio Single use syringe
US5531691A (en) 1994-02-14 1996-07-02 Univec Inc. Single use syringe assembly
US5562623A (en) 1994-02-14 1996-10-08 Univec Single-use syringe assembly including spring clip lock and plunger
US5674204A (en) * 1995-09-19 1997-10-07 Becton Dickinson And Company Medication delivery pen cap actuated dose delivery clutch
US5582595A (en) 1995-09-28 1996-12-10 Habley Medical Technology Corporation Aspirating syringe having a plunger guide for a reciprocating plunger assembly
US5819983A (en) 1995-11-22 1998-10-13 Camelot Sysems, Inc. Liquid dispensing system with sealing augering screw and method for dispensing
JPH09225031A (ja) * 1996-02-28 1997-09-02 Terumo Corp 定量分与器
US6533758B1 (en) * 1997-07-18 2003-03-18 Liebel-Flarsheim Company Adapter and syringe for front-loading medical fluid injector
CZ297361B6 (cs) * 1998-01-30 2006-11-15 Novo Nordisk A/S Injekcní stríkacka
US6221053B1 (en) * 1998-02-20 2001-04-24 Becton, Dickinson And Company Multi-featured medication delivery pen
JP3832148B2 (ja) 1999-02-08 2006-10-11 フジノン株式会社 シリンジ用アダプタ装置
WO2001019428A2 (en) 1999-09-13 2001-03-22 Vitro Diagnostics, Inc. Multi-dose syringe driver
US6231550B1 (en) 1999-12-02 2001-05-15 Joshua D. Laughlin One-handed single grip position aspiration and injection syringe
US6533756B2 (en) 2000-02-10 2003-03-18 Univec, Inc. Single use syringe
US7500959B2 (en) 2000-10-05 2009-03-10 Novo Nordisk A/S Medication delivery system with improved dose accuracy
DE10235468A1 (de) 2001-08-08 2003-04-30 Ntn Toyo Bearing Co Ltd Spritzenpumpe
US7798185B2 (en) 2005-08-01 2010-09-21 Medical Instill Technologies, Inc. Dispenser and method for storing and dispensing sterile food product
JP4405802B2 (ja) 2001-10-16 2010-01-27 メディカル・インスティル・テクノロジーズ・インコーポレイテッド 計量された量の物質を供給するための、密閉チャンバ及び一方向弁を備えたディスペンサ
AUPS053902A0 (en) 2002-02-14 2002-03-07 Hawthorne, Matthew Aspiration device
US6719735B1 (en) 2003-02-28 2004-04-13 Gammon Technical Products, Inc. Syringe adapter
CN1950124B (zh) 2004-01-12 2010-11-10 Ⅰ科学外科公司 一种输送粘性材料的注射器
WO2005097240A1 (en) 2004-03-30 2005-10-20 Eli Lilly And Company Medication dispensing apparatus with gear set having drive member accommodating opening
JP5178202B2 (ja) * 2004-12-01 2013-04-10 ノボ・ノルデイスク・エー／エス 注入装置
PT1868669T (pt) 2005-04-15 2017-01-17 Unitract Syringe Pty Ltd Seringa de retração controlada e seu êmbolo
WO2006119570A1 (en) 2005-05-12 2006-11-16 Unitract Syringe Pty Ltd Improved controlled retraction syringe and plunger therefor
DE102005023823B4 (de) * 2005-05-24 2022-11-17 Tecpharma Licensing Ag Dosiervorrichtung für eine Injektionsvorrichtung und Injektionsvorrichtung mit einer solchen Dosiervorrichtung
US7611495B1 (en) 2005-10-07 2009-11-03 Gianturco Michael C Device for manually controlling delivery rate of a hypodermic syringe and syringe having same
AU2006338189B2 (en) 2006-02-14 2012-01-19 Battelle Memorial Institute Accurate metering system
US8057427B2 (en) 2007-05-09 2011-11-15 Meridian Medical Technologies, Inc. Drug delivery system with a small amount of a therapeutic agent
ES2354016T3 (es) 2007-05-14 2011-03-09 Shl Group Ab Dispositivo de administración.
NZ595031A (en) 2007-07-02 2012-02-24 Unitract Syringe Pty Ltd Automatically retracting syringe with spring based mechanisim
CN201168280Y (zh) * 2008-03-28 2008-12-24 甘肃成纪生物药业有限公司 一种卡式瓶注射器
US8267900B2 (en) * 2008-05-02 2012-09-18 Sanofi-Aventis Deutschland Gmbh Medication delivery device
NZ588808A (en) * 2008-05-02 2012-04-27 Sanofi Aventis Deutschland Medication delivery device including piston with two threaded sections
BRPI0922692B8 (pt) * 2008-12-04 2021-06-22 Sanofi Aventis Deutschland dispositivo de injeção
PL4019065T3 (pl) * 2009-12-01 2024-01-08 Becton, Dickinson And Company Pen do iniekcji z cofaniem oraz kontrolą ostatniej dawki leku
AU2010336003B2 (en) 2009-12-22 2014-07-03 Unitract Syringe Pty Ltd Retractable syringe with improved delivery efficiency and locking system
CN102869398B (zh) 2010-05-04 2015-08-26 尤尼特拉克特注射器公司 注射器筒适配器和针组件
RU2650207C2 (ru) * 2011-12-08 2018-04-11 Юнитрект Сириндж Пти Лтд Механизм контроля точной величины дозы и шприц для доставки лекарства

Also Published As

Publication number Publication date
US9345839B2 (en) 2016-05-24
IL232733B (en) 2019-01-31
AU2012347818A1 (en) 2014-06-12
JP2015500095A (ja) 2015-01-05
BR112014013632A2 (pt) 2017-06-13
WO2013086167A1 (en) 2013-06-13
IL232733A0 (en) 2014-07-31
AU2012347818B2 (en) 2017-03-30
MX2014006694A (es) 2014-07-14
EP2788054B1 (en) 2018-04-25
US20130150803A1 (en) 2013-06-13
CN103998080A (zh) 2014-08-20
JP6298946B2 (ja) 2018-03-28
MX351572B (es) 2017-10-18
CA2857506A1 (en) 2013-06-13
RU2014126753A (ru) 2016-01-27
CN103998080B (zh) 2017-03-08
JP6446714B2 (ja) 2019-01-09
JP2018061832A (ja) 2018-04-19
BR112014013632A8 (pt) 2017-06-13
EP2788054A1 (en) 2014-10-15
ZA201404088B (en) 2016-08-31
IN2014CN04000A (enExample) 2015-10-23
TWI555544B (zh) 2016-11-01
PT2788054T (pt) 2018-07-30
DK2788054T3 (en) 2018-08-06
RU2650207C2 (ru) 2018-04-11
HK1200125A1 (en) 2015-07-31
KR20140105457A (ko) 2014-09-01
TW201330889A (zh) 2013-08-01

Similar Documents

Publication Publication Date Title
US9345839B2 (en) Accurate dose control mechanisms and drug delivery syringes
US10328211B2 (en) Automatic self-dispensing accurate dose drug delivery syringes
US10213556B2 (en) Accurate dose control mechanisms and drug delivery syringes
AU2014328035B2 (en) Automatic self-dispensing accurate dose drug delivery syringes
JP7568670B2 (ja) 注射ペン
EP3463517A1 (en) Accurate dose control mechanisms and drug delivery syringes
CN111491680B (zh) 用于精确剂量输送的装置和方法
EP3442623B1 (en) Accurate, precise microliter dosing syringe
EP3573688A1 (en) A prefilled injection device with cleaning chamber
HK1200125B (en) Accurate dose control mechanisms and drug delivery syringes
JP2020121157A (ja) 正確な投与量制御機構および薬物送達注射器
HK40000032B (en) Accurate, precise microliter dosing syringe
HK40000032A (en) Accurate, precise microliter dosing syringe

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20171205

MKLA Lapsed

Effective date: 20201207