TWI555544B - 精準劑量控制機制及藥品傳送注射器及其製造方法 - Google Patents
精準劑量控制機制及藥品傳送注射器及其製造方法 Download PDFInfo
- Publication number
- TWI555544B TWI555544B TW101146033A TW101146033A TWI555544B TW I555544 B TWI555544 B TW I555544B TW 101146033 A TW101146033 A TW 101146033A TW 101146033 A TW101146033 A TW 101146033A TW I555544 B TWI555544 B TW I555544B
- Authority
- TW
- Taiwan
- Prior art keywords
- plunger
- syringe
- screw
- dose
- control mechanism
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31526—Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31573—Accuracy improving means
- A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features; Drive mechanisms or modes for piston rods
- A61M5/31583—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it
- A61M5/31585—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3137—Syringe barrels with finger grip means, e.g. for easy manipulation of the syringe rod
- A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
- F04C2270/00—Control; Monitoring or safety arrangements
- F04C2270/04—Force
- F04C2270/041—Controlled or regulated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161568509P | 2011-12-08 | 2011-12-08 | |
| PCT/US2012/068210 WO2013086167A1 (en) | 2011-12-08 | 2012-12-06 | Accurate dose control mechanisms and drug delivery syringes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201330889A TW201330889A (zh) | 2013-08-01 |
| TWI555544B true TWI555544B (zh) | 2016-11-01 |
Family
ID=47472025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW101146033A TWI555544B (zh) | 2011-12-08 | 2012-12-07 | 精準劑量控制機制及藥品傳送注射器及其製造方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9345839B2 (enExample) |
| EP (1) | EP2788054B1 (enExample) |
| JP (2) | JP6298946B2 (enExample) |
| KR (1) | KR20140105457A (enExample) |
| CN (1) | CN103998080B (enExample) |
| AU (1) | AU2012347818B2 (enExample) |
| BR (1) | BR112014013632A2 (enExample) |
| CA (1) | CA2857506C (enExample) |
| DK (1) | DK2788054T3 (enExample) |
| IL (1) | IL232733B (enExample) |
| IN (1) | IN2014CN04000A (enExample) |
| MX (1) | MX351572B (enExample) |
| PT (1) | PT2788054T (enExample) |
| RU (1) | RU2650207C2 (enExample) |
| TW (1) | TWI555544B (enExample) |
| WO (1) | WO2013086167A1 (enExample) |
| ZA (1) | ZA201404088B (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
| WO2012051575A2 (en) | 2010-10-15 | 2012-04-19 | Iscience Interventional Corporation | Device for ocular access |
| WO2017204787A1 (en) * | 2011-12-08 | 2017-11-30 | Unitract Syringe Pty Ltd | Accurate dose control mechanisms and drug delivery syringes |
| JP6298946B2 (ja) * | 2011-12-08 | 2018-03-28 | ユーエヌエル ホールディングス エルエルシーUNL Holdings LLC | 正確な投与制御機構及び薬物送達用注射器 |
| AU2013342275B2 (en) | 2012-11-08 | 2017-11-09 | Clearside Biomedical, Inc. | Methods and devices for the treatment of ocular diseases in human subjects |
| SG10201702674PA (en) | 2013-05-03 | 2017-06-29 | Clearside Biomedical Inc | Apparatus and methods for ocular injection |
| WO2014197317A1 (en) | 2013-06-03 | 2014-12-11 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
| WO2015009868A1 (en) | 2013-07-16 | 2015-01-22 | Unitract Syringe Pty Ltd | Syringes for repetitive mixing and delivery of injectables |
| US20150158926A1 (en) | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
| KR101472821B1 (ko) * | 2014-05-14 | 2014-12-16 | 김준우 | 성분 분리기 |
| WO2015196085A2 (en) | 2014-06-20 | 2015-12-23 | Clearside Biomedical, Inc. | Variable diameter cannula and methods for controlling insertion depth for medicament delivery |
| US10049189B2 (en) * | 2014-09-29 | 2018-08-14 | Min Wei | Method for developing parenteral therapeutic product with drug delivery device through clinical trial |
| USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
| JP6471029B2 (ja) * | 2015-04-10 | 2019-02-13 | 株式会社ダイセル | 注射器 |
| US10702658B2 (en) | 2015-07-12 | 2020-07-07 | Patients Pending Ltd. | Cover for liquid delivery system with integrated plunger position sensing, and corresponding method |
| EP3187213A1 (en) * | 2015-12-29 | 2017-07-05 | Galderma S.A. | Syringe with click mechanism |
| US10390901B2 (en) | 2016-02-10 | 2019-08-27 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
| WO2017147404A1 (en) * | 2016-02-25 | 2017-08-31 | Academia Sinica | Syringe apparatus for stirring and delivering composition containing cells |
| EP3442718B1 (en) * | 2016-04-13 | 2019-08-07 | 3M Innovative Properties Company | A syringe for dispensing a dental substance |
| JP7076106B2 (ja) | 2016-04-15 | 2022-05-27 | 参天製薬株式会社 | 正確で優れた精度のマイクロリットル投薬シリンジ |
| JP2019514581A (ja) | 2016-05-02 | 2019-06-06 | クリアサイド バイオメディカル,インコーポレイテッド | 眼の薬物送達のためのシステムおよび方法 |
| AU2016408375A1 (en) * | 2016-05-24 | 2019-01-03 | Unl Holdings Llc | Accurate dose control mechanisms and drug delivery syringes |
| WO2017219018A2 (en) * | 2016-06-17 | 2017-12-21 | Becton, Dickinson And Company | Method and apparatus for wetting internal fluid path surfaces of a fluid port to increase ultrasonic signal transmission |
| CN106038053B (zh) * | 2016-07-05 | 2018-11-20 | 颜繁诚 | 眼球后注药装置 |
| US10973681B2 (en) | 2016-08-12 | 2021-04-13 | Clearside Biomedical, Inc. | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
| US11083851B2 (en) | 2016-09-17 | 2021-08-10 | Ethan Pedde | Methods, systems and devices for administering medication |
| WO2018204515A1 (en) | 2017-05-02 | 2018-11-08 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
| EP3638346B1 (en) | 2017-06-16 | 2025-10-15 | Credence Medsystems, Inc. | System and method for safety syringe |
| DE102017005779A1 (de) | 2017-06-19 | 2018-12-20 | Giesecke+Devrient Mobile Security Gmbh | Mikrooptisches Element mit Farbwechsel |
| USD1141122S1 (en) | 2017-09-15 | 2026-08-11 | Ethan Pedde | Volume limiter device |
| FR3072297B1 (fr) * | 2017-10-17 | 2023-05-12 | Edix Sa | Dispositif d'injection manuelle |
| IL318292A (en) | 2017-12-13 | 2025-03-01 | Regeneron Pharma | Devices and methods for administering precise doses |
| US11419991B2 (en) | 2018-11-13 | 2022-08-23 | Credence Medsystems, Inc. | System and method for microdose injection |
| RU2710348C1 (ru) * | 2019-03-11 | 2019-12-25 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ярославский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Универсальный одноразовый шприц |
| MX2021012304A (es) * | 2019-04-09 | 2021-12-15 | Congruence Medical Solutions Llc | Dispositivo de inyeccion. |
| PE20240329A1 (es) | 2019-06-05 | 2024-02-27 | Regeneron Pharma | Dispositivos y metodos para administracion de dosis de precision |
| IL267610A (en) * | 2019-06-24 | 2019-10-31 | Dali Medical Devices Ltd | dose monitoring |
| EP4058108A2 (en) * | 2019-11-14 | 2022-09-21 | Congruence Medical Solutions, LLC | Variable dosing syringe |
| JP2020121157A (ja) * | 2020-04-10 | 2020-08-13 | ユーエヌエル ホールディングス エルエルシーUNL Holdings LLC | 正確な投与量制御機構および薬物送達注射器 |
| CN111529826B (zh) * | 2020-05-28 | 2025-06-20 | 南京康友医疗科技有限公司 | 一种注射装置 |
| US11883635B2 (en) | 2020-06-17 | 2024-01-30 | Credence MedSystems | System and method for microdose injection |
| WO2022039196A1 (ja) * | 2020-08-20 | 2022-02-24 | テルモ株式会社 | プレフィルドシリンジ |
| US20220280389A1 (en) * | 2021-03-06 | 2022-09-08 | Control, Ltd. | Syringe Assembly & Method for Accurate Dosing |
| CN113578697B (zh) * | 2021-07-23 | 2023-07-28 | 信利光电股份有限公司 | 一种点导电银浆用注射器 |
| US12649031B2 (en) | 2021-09-08 | 2026-06-09 | Regeneron Pharmaceuticals, Inc. | Methods for delivering agents with pre-filled syringes to minimize intraocular inflammation |
| USD1120314S1 (en) | 2022-11-30 | 2026-03-24 | Regeneron Pharmaceuticals, Inc. | Dose delivery device |
| EP4673194A1 (en) * | 2023-02-28 | 2026-01-07 | Stephen Terence Dunne | Controlled dose syringe |
| WO2025154005A1 (en) * | 2024-01-19 | 2025-07-24 | Gupta Nalini K | An aseptic syringe for collection of samples |
| WO2025199106A1 (en) * | 2024-03-19 | 2025-09-25 | Halozyme, Inc. | Autoinjector |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3596659A (en) * | 1968-12-09 | 1971-08-03 | Nuclear Associates Inc | A shielding holder for a syringe |
| CN201168280Y (zh) * | 2008-03-28 | 2008-12-24 | 甘肃成纪生物药业有限公司 | 一种卡式瓶注射器 |
| US20090275914A1 (en) * | 2008-05-02 | 2009-11-05 | Sanofi-Aventis Deutschland Gmbh | Medication Delivery Device |
| US7867202B2 (en) * | 2005-05-24 | 2011-01-11 | Tecpharma Licensing Ag | Threaded rod and dose setting mechanism for an injection device |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2943624A (en) | 1958-04-17 | 1960-07-05 | Mavis M Alquist | Quantitative indicator for syringes |
| US4018223A (en) | 1974-12-09 | 1977-04-19 | Andros Incorporated | Dosage control device |
| US4444335A (en) | 1981-09-14 | 1984-04-24 | Merck & Co., Inc. | Delivery of adjustable quantities of materials |
| US4465478A (en) | 1982-10-14 | 1984-08-14 | Collagen Corporation | Syringe force amplification device |
| GB2140302A (en) | 1983-05-26 | 1984-11-28 | Microsurgical Equipment Ltd | An aspiration adaptor for a syringe |
| FR2583291A1 (fr) | 1985-06-14 | 1986-12-19 | Hazon Bernard | Dispositif d'avancement pas a pas du piston de seringues par double vis coaxiale avec controle du debit d'injection. application aux injections medicamenteuses intra-dermiques repetitives |
| US4687472A (en) | 1986-11-12 | 1987-08-18 | Gross Daniel A | Injection assisting apparatus |
| GB8713810D0 (en) | 1987-06-12 | 1987-07-15 | Hypoguard Uk Ltd | Measured dose dispensing device |
| EP0341281B1 (en) * | 1987-11-06 | 1993-03-24 | ELLGASS, Louis Paul | Non-reusable syringe |
| US5135511A (en) | 1990-08-22 | 1992-08-04 | Becton, Dickinson And Company | Assembly for aspirating tissue, including adapter for syringe |
| US5115816A (en) | 1991-01-24 | 1992-05-26 | Peter F. Lee, Inc. | Single-hand controlled fine needle aspiration device |
| AR243387A1 (es) | 1991-10-03 | 1993-08-31 | Cesar Gabriel Corsich | Jeringa hipodermica con embolo trabable para evitar su recarga y reutilizacion. |
| US5378233A (en) | 1992-11-18 | 1995-01-03 | Habley Medical Technology Corporation | Selected dose pharmaceutical dispenser |
| US5346475A (en) | 1993-10-27 | 1994-09-13 | Edward Gregorio | Single use syringe |
| US5531691A (en) | 1994-02-14 | 1996-07-02 | Univec Inc. | Single use syringe assembly |
| US5562623A (en) | 1994-02-14 | 1996-10-08 | Univec | Single-use syringe assembly including spring clip lock and plunger |
| US5674204A (en) * | 1995-09-19 | 1997-10-07 | Becton Dickinson And Company | Medication delivery pen cap actuated dose delivery clutch |
| US5582595A (en) | 1995-09-28 | 1996-12-10 | Habley Medical Technology Corporation | Aspirating syringe having a plunger guide for a reciprocating plunger assembly |
| US5819983A (en) | 1995-11-22 | 1998-10-13 | Camelot Sysems, Inc. | Liquid dispensing system with sealing augering screw and method for dispensing |
| JPH09225031A (ja) * | 1996-02-28 | 1997-09-02 | Terumo Corp | 定量分与器 |
| US6533758B1 (en) * | 1997-07-18 | 2003-03-18 | Liebel-Flarsheim Company | Adapter and syringe for front-loading medical fluid injector |
| JP3270761B2 (ja) * | 1998-01-30 | 2002-04-02 | ノボ ノルディスク アクティーゼルスカブ | 注射器 |
| US6221053B1 (en) * | 1998-02-20 | 2001-04-24 | Becton, Dickinson And Company | Multi-featured medication delivery pen |
| JP3832148B2 (ja) | 1999-02-08 | 2006-10-11 | フジノン株式会社 | シリンジ用アダプタ装置 |
| EP1257307A2 (en) | 1999-09-13 | 2002-11-20 | Vitro Diagnostics, Inc. | Multi-dose syringe driver |
| US6231550B1 (en) | 1999-12-02 | 2001-05-15 | Joshua D. Laughlin | One-handed single grip position aspiration and injection syringe |
| US6533756B2 (en) | 2000-02-10 | 2003-03-18 | Univec, Inc. | Single use syringe |
| US7500959B2 (en) | 2000-10-05 | 2009-03-10 | Novo Nordisk A/S | Medication delivery system with improved dose accuracy |
| DE10235468A1 (de) | 2001-08-08 | 2003-04-30 | Ntn Toyo Bearing Co Ltd | Spritzenpumpe |
| US7798185B2 (en) | 2005-08-01 | 2010-09-21 | Medical Instill Technologies, Inc. | Dispenser and method for storing and dispensing sterile food product |
| WO2003033363A1 (en) | 2001-10-16 | 2003-04-24 | Medical Instill Technologies, Inc. | Dispenser with sealed chamber and one-way valve for providing metered amounts of substances |
| AUPS053902A0 (en) | 2002-02-14 | 2002-03-07 | Hawthorne, Matthew | Aspiration device |
| US6719735B1 (en) | 2003-02-28 | 2004-04-13 | Gammon Technical Products, Inc. | Syringe adapter |
| CN101912325A (zh) | 2004-01-12 | 2010-12-15 | i科学外科公司 | 一种输送粘性材料的注射器 |
| EP1732628B1 (en) | 2004-03-30 | 2011-09-28 | Eli Lilly & Company | Medication dispensing apparatus with gear set having drive member accommodating opening |
| DE602005026595D1 (de) * | 2004-12-01 | 2011-04-07 | Novo Nordisk As | Injektionsvorrichtung |
| EP1868669B1 (en) | 2005-04-15 | 2016-10-19 | Unitract Syringe Pty Ltd | Controlled retraction syringe and plunger therefor |
| WO2006119570A1 (en) | 2005-05-12 | 2006-11-16 | Unitract Syringe Pty Ltd | Improved controlled retraction syringe and plunger therefor |
| US7611495B1 (en) | 2005-10-07 | 2009-11-03 | Gianturco Michael C | Device for manually controlling delivery rate of a hypodermic syringe and syringe having same |
| WO2007094833A1 (en) | 2006-02-14 | 2007-08-23 | Battelle Memorial Institute | Accurate metering system |
| US8057427B2 (en) | 2007-05-09 | 2011-11-15 | Meridian Medical Technologies, Inc. | Drug delivery system with a small amount of a therapeutic agent |
| EP2162230B1 (en) | 2007-05-14 | 2010-11-03 | SHL Group AB | Delivery device |
| NZ595031A (en) | 2007-07-02 | 2012-02-24 | Unitract Syringe Pty Ltd | Automatically retracting syringe with spring based mechanisim |
| UA101498C2 (ru) * | 2008-05-02 | 2013-04-10 | Санофі-Авентіс Дойчланд Гмбх | Устройство подачи лекарственного средства |
| ES2648867T3 (es) * | 2008-12-04 | 2018-01-08 | Sanofi-Aventis Deutschland Gmbh | Dispositivo de inyección con medios de retención para impedir movimientos no intencionados de un vástago de pistón |
| EP3733232B1 (en) * | 2009-12-01 | 2021-12-29 | Becton, Dickinson and Company | Injection pen with dial back and last dose control |
| WO2011075760A1 (en) | 2009-12-22 | 2011-06-30 | Unitract Syringe Pty Ltd | Retractable syringe with improved delivery efficiency and locking system |
| EP2571552A4 (en) | 2010-05-04 | 2014-11-26 | Unitract Syringe Pty Ltd | SYRINGE CYLINDER ADAPTER AND NEEDLE ASSEMBLY |
| JP6298946B2 (ja) * | 2011-12-08 | 2018-03-28 | ユーエヌエル ホールディングス エルエルシーUNL Holdings LLC | 正確な投与制御機構及び薬物送達用注射器 |
-
2012
- 2012-12-06 JP JP2014546069A patent/JP6298946B2/ja not_active Expired - Fee Related
- 2012-12-06 WO PCT/US2012/068210 patent/WO2013086167A1/en not_active Ceased
- 2012-12-06 CA CA2857506A patent/CA2857506C/en not_active Expired - Fee Related
- 2012-12-06 DK DK12809422.4T patent/DK2788054T3/en active
- 2012-12-06 RU RU2014126753A patent/RU2650207C2/ru not_active IP Right Cessation
- 2012-12-06 BR BR112014013632A patent/BR112014013632A2/pt not_active Application Discontinuation
- 2012-12-06 US US13/707,201 patent/US9345839B2/en active Active
- 2012-12-06 CN CN201280060269.8A patent/CN103998080B/zh not_active Expired - Fee Related
- 2012-12-06 IN IN4000CHN2014 patent/IN2014CN04000A/en unknown
- 2012-12-06 PT PT128094224T patent/PT2788054T/pt unknown
- 2012-12-06 MX MX2014006694A patent/MX351572B/es active IP Right Grant
- 2012-12-06 KR KR1020147015320A patent/KR20140105457A/ko not_active Abandoned
- 2012-12-06 AU AU2012347818A patent/AU2012347818B2/en not_active Ceased
- 2012-12-06 EP EP12809422.4A patent/EP2788054B1/en not_active Not-in-force
- 2012-12-07 TW TW101146033A patent/TWI555544B/zh not_active IP Right Cessation
-
2014
- 2014-05-21 IL IL232733A patent/IL232733B/en active IP Right Grant
- 2014-06-05 ZA ZA2014/04088A patent/ZA201404088B/en unknown
-
2017
- 2017-08-23 JP JP2017160466A patent/JP6446714B2/ja not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3596659A (en) * | 1968-12-09 | 1971-08-03 | Nuclear Associates Inc | A shielding holder for a syringe |
| US7867202B2 (en) * | 2005-05-24 | 2011-01-11 | Tecpharma Licensing Ag | Threaded rod and dose setting mechanism for an injection device |
| CN201168280Y (zh) * | 2008-03-28 | 2008-12-24 | 甘肃成纪生物药业有限公司 | 一种卡式瓶注射器 |
| US20090275914A1 (en) * | 2008-05-02 | 2009-11-05 | Sanofi-Aventis Deutschland Gmbh | Medication Delivery Device |
Also Published As
| Publication number | Publication date |
|---|---|
| TW201330889A (zh) | 2013-08-01 |
| JP2015500095A (ja) | 2015-01-05 |
| MX2014006694A (es) | 2014-07-14 |
| JP2018061832A (ja) | 2018-04-19 |
| BR112014013632A8 (pt) | 2017-06-13 |
| WO2013086167A1 (en) | 2013-06-13 |
| US9345839B2 (en) | 2016-05-24 |
| IN2014CN04000A (enExample) | 2015-10-23 |
| MX351572B (es) | 2017-10-18 |
| IL232733B (en) | 2019-01-31 |
| HK1200125A1 (en) | 2015-07-31 |
| DK2788054T3 (en) | 2018-08-06 |
| CN103998080B (zh) | 2017-03-08 |
| EP2788054A1 (en) | 2014-10-15 |
| AU2012347818B2 (en) | 2017-03-30 |
| CA2857506A1 (en) | 2013-06-13 |
| RU2014126753A (ru) | 2016-01-27 |
| JP6446714B2 (ja) | 2019-01-09 |
| KR20140105457A (ko) | 2014-09-01 |
| RU2650207C2 (ru) | 2018-04-11 |
| IL232733A0 (en) | 2014-07-31 |
| JP6298946B2 (ja) | 2018-03-28 |
| BR112014013632A2 (pt) | 2017-06-13 |
| CN103998080A (zh) | 2014-08-20 |
| AU2012347818A1 (en) | 2014-06-12 |
| US20130150803A1 (en) | 2013-06-13 |
| CA2857506C (en) | 2020-01-14 |
| EP2788054B1 (en) | 2018-04-25 |
| ZA201404088B (en) | 2016-08-31 |
| PT2788054T (pt) | 2018-07-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103998080B (zh) | 精准剂量控制装置及药品传送注射器 | |
| JP7568670B2 (ja) | 注射ペン | |
| US10213556B2 (en) | Accurate dose control mechanisms and drug delivery syringes | |
| US10328211B2 (en) | Automatic self-dispensing accurate dose drug delivery syringes | |
| AU2014328035B2 (en) | Automatic self-dispensing accurate dose drug delivery syringes | |
| KR20190013854A (ko) | 정확 투여 제어 메커니즘 및 약물 전달 주사기 | |
| US10603444B2 (en) | Automatic injection device with variable dosing | |
| EP2470243B1 (en) | Assembly kit for preparing of a pre-filled syringe | |
| US20240374824A1 (en) | Medical delivery device | |
| JP2020121157A (ja) | 正確な投与量制御機構および薬物送達注射器 | |
| HK1200125B (en) | Accurate dose control mechanisms and drug delivery syringes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |