CA2856329A1 - Compositions and methods for treating glioma - Google Patents

Compositions and methods for treating glioma Download PDF

Info

Publication number
CA2856329A1
CA2856329A1 CA2856329A CA2856329A CA2856329A1 CA 2856329 A1 CA2856329 A1 CA 2856329A1 CA 2856329 A CA2856329 A CA 2856329A CA 2856329 A CA2856329 A CA 2856329A CA 2856329 A1 CA2856329 A1 CA 2856329A1
Authority
CA
Canada
Prior art keywords
peptide
csf
seq
glioma
set forth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2856329A
Other languages
English (en)
French (fr)
Inventor
Bozena KAMINSKA-KACZMAREK
Malgorzata SIELSKA
Pawel Wisniewski
Aleksandra ELLERT-MIKLASZEWSKA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glia Sp zoo
Original Assignee
NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY filed Critical NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY
Publication of CA2856329A1 publication Critical patent/CA2856329A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CA2856329A 2011-11-17 2012-11-18 Compositions and methods for treating glioma Abandoned CA2856329A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161561080P 2011-11-17 2011-11-17
US61/561,080 2011-11-17
US201261583745P 2012-01-06 2012-01-06
US61/583,745 2012-01-06
PCT/IB2012/056533 WO2013072901A2 (en) 2011-11-17 2012-11-18 Compositions and methods for treating glioma

Publications (1)

Publication Number Publication Date
CA2856329A1 true CA2856329A1 (en) 2013-05-23

Family

ID=47358252

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2856329A Abandoned CA2856329A1 (en) 2011-11-17 2012-11-18 Compositions and methods for treating glioma

Country Status (7)

Country Link
US (2) US9453050B2 (cg-RX-API-DMAC7.html)
EP (1) EP2780363B1 (cg-RX-API-DMAC7.html)
JP (1) JP6426001B2 (cg-RX-API-DMAC7.html)
KR (1) KR20140103122A (cg-RX-API-DMAC7.html)
CA (1) CA2856329A1 (cg-RX-API-DMAC7.html)
IL (1) IL232648B (cg-RX-API-DMAC7.html)
WO (1) WO2013072901A2 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201220573D0 (en) 2012-11-15 2013-01-02 Univ Central Lancashire Methods of diagnosing proliferative disorders
DE102014207498A1 (de) * 2014-04-17 2015-10-22 Universitätsklinikum Hamburg-Eppendorf Viraler Vektor für den zielgerichteten Gentransfer in Gehirn und Rückenmark
KR102507694B1 (ko) * 2014-09-26 2023-03-08 내셔널 유니버시티 오브 싱가포르 Th-gm 세포 기능 조절 방법 및 조성물
US11078264B2 (en) 2018-10-17 2021-08-03 University Of Connecticut Inhibiting granulocyte macrophage-colony stimulating factor (GM-CSF) prevents preterm birth
EP3886888A4 (en) * 2018-11-28 2022-09-28 Glia Sp. z o.o. COMPOSITIONS AND METHODS OF TREATMENT OF GLIOMA
CN112007142B (zh) * 2019-05-31 2025-04-22 生物蚕茧研究所股份有限公司 向抗炎m2表型小胶质细胞的极性转化促进剂
PL441229A1 (pl) * 2022-05-19 2023-11-20 Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polska Akademia Nauk Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych
KR102899196B1 (ko) * 2023-01-20 2025-12-12 (주) 넥셀 치주염 및 임플란트 주변염 예방 또는 치료용 재조합 단백질 및 이를 포함하는 치주염 및 임플란트 주변염 예방 또는 치료용 조성물
CN116650650A (zh) * 2023-06-12 2023-08-29 郑州大学 一种抑制食管鳞癌中肿瘤相关巨噬细胞浸润的方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150090A (en) 1986-01-09 2000-11-21 Massachusetts Institute Of Technology Nuclear factors associated with transcriptional regulation
NZ234479A (en) * 1989-07-14 1992-03-26 Schering Corp Antagonists of gm-csf derived from the carboxyl terminus, antibodies, hybridomas and pharmaceutical compositions containing anti-idiotypic antibodies
CA2064814C (en) * 1989-08-11 2004-06-08 Nicos Anthony Nicola Granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof
AUPN780096A0 (en) * 1996-01-30 1996-02-22 Medvet Science Pty. Ltd. Cytokine antagonists and agonists
US5837231A (en) * 1996-06-27 1998-11-17 Regents Of The University Of Minnesota GM-CSF administration for the treatment and prevention of recurrence of brain tumors
US6372720B1 (en) 1998-02-05 2002-04-16 Kenneth J. Longmuir Liposome fusion and delivery vehicle
CA2288680A1 (en) 1998-11-12 2000-05-12 Jcr Pharmaceuticals Co., Ltd. Modulation of cell proliferative disorders by cyclic rgd
US6551990B2 (en) * 1998-12-07 2003-04-22 University Of Washington Methods of inhibiting ectopic calcification
AU783992B2 (en) 1998-12-23 2006-01-12 G.D. Searle Llc Method of using a cyclooxygenase-2 inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6521593B1 (en) 1999-02-01 2003-02-18 Childrens Hospital Los Angeles Methods for inhibiting brain tumor growth
NZ522066A (en) * 2000-03-30 2004-08-27 Dendreon Corp Compositions and methods for dendritic cell-based immunotherapy
US7767802B2 (en) 2001-01-09 2010-08-03 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of anti-apoptotic genes
US7611711B2 (en) * 2001-01-17 2009-11-03 Vegenics Limited VEGFR-3 inhibitor materials and methods
WO2003015698A2 (en) 2001-08-13 2003-02-27 University Of Pittsburgh Application of lipid vehicles and use for drug delivery
AU2003276828A1 (en) * 2002-05-10 2004-03-11 Children's Medical Center Corporation Minicell display and products therefrom
US7790687B2 (en) * 2005-02-18 2010-09-07 Proximagen Ltd. Treatment for neurodegeneration
EP2377884A1 (en) * 2005-05-10 2011-10-19 Neoloch Aps Neuritogenic peptides
AU2006292203A1 (en) * 2005-09-21 2007-03-29 Dask Technologies, Llc Methods and compositions for organ and tissue functionality
WO2007084670A2 (en) 2006-01-18 2007-07-26 Merck Patent Gmbh Specific therapy using integrin ligands for treating cancer
SI2423229T1 (sl) * 2006-03-27 2013-09-30 Medimmune Limited Vezni ÄŤlen za receptor GM-CSF
WO2008112659A2 (en) 2007-03-09 2008-09-18 Pathologica Llc Regulation of osteopontin
DK2201138T3 (en) 2007-10-16 2015-05-18 Ventana Med Syst Inc GRADING, STAGE DETERMINATION AND FORECAST OF CANCER USING osteopontin-C
KR101768792B1 (ko) * 2008-01-22 2017-08-16 아라임 파마슈티칼즈, 인크. 조직 손상 관련 질환 및 장애를 예방 및 치료하기 위한 조직 보호 펩티드 및 펩티드 유사체
EP2346524A2 (en) 2008-11-20 2011-07-27 Merck Patent GmbH New therapy and medicament using integrin ligands for treating cancer
EP2445534A2 (en) 2009-05-25 2012-05-02 Merck Patent GmbH Continuous administration of cilengitide in cancer treatments
CA2798074A1 (en) * 2010-04-27 2011-11-03 The Johns Hopkins University Immunogenic compositions and methods for treating neoplasia

Also Published As

Publication number Publication date
EP2780363B1 (en) 2019-07-03
WO2013072901A2 (en) 2013-05-23
US20140256628A1 (en) 2014-09-11
EP2780363A2 (en) 2014-09-24
JP2014533681A (ja) 2014-12-15
IL232648A0 (en) 2014-06-30
KR20140103122A (ko) 2014-08-25
US9453050B2 (en) 2016-09-27
JP6426001B2 (ja) 2018-11-21
WO2013072901A3 (en) 2013-07-25
US20170035851A1 (en) 2017-02-09
IL232648B (en) 2021-12-01

Similar Documents

Publication Publication Date Title
US9453050B2 (en) Compositions for treating glioma
US20130273057A1 (en) Methods and compositions for the treatment and diagnosis of vascular inflammatory disorders or endothelial cell disorders
US8871205B2 (en) Methods and compositions for the treatment of immune disorders
EP3431498A1 (en) Treatment of fibrosis of the gastrointestinal tract with antibodies which prevent il-11:il-11ralpha interaction
US20180193382A1 (en) Methods of treating cancer, infectious disease, and autoimmune disease using cxc chemokines
CN102348796B (zh) 新型癌抗原eEF2
Li et al. Pathogenic Tconvs promote inflammatory macrophage polarization through GM‐CSF and exacerbate abdominal aortic aneurysm formation
JP5847590B2 (ja) 生体材料およびその使用
US20100266579A1 (en) Treatment of inflammatory diseases
EP3532494A2 (en) Methods and compositions for modulaton of transforming growth factor beta-regulated functions
CN106029101A (zh) 生物材料和其治疗用途
US9546366B2 (en) Replication factor C-40 (RFC40/RFC2) as a prognostic marker and target in estrogen positive and negative and triple negative breast cancer
CN102666877B (zh) 治疗神经病理性疼痛的组合物及方法
US9970012B2 (en) Replication factor C-40 (RFC40/RFC2) as a prognostic marker and target in estrogen positive and negative and triple negative breast cancer
SK8882002A3 (en) Human heparanase-related polypeptide and nucleic acid
KR101522729B1 (ko) 파골세포 융합의 새로운 바이오 마커인 piro
KR101699567B1 (ko) JunB의 발현 또는 활성 억제제를 유효성분으로 포함하는 면역질환의 예방 또는 치료용 조성물
JP2024511569A (ja) 免疫増強剤
US20220072100A1 (en) Methods of treating cancer, infectious disease, and autoimmune disease using chemokines
WO2022192528A1 (en) Gal3bp polypeptide compositions and methods for treatment of cancer and determining treatment responsiveness
US20150273019A1 (en) Method of treating wounds
WO2012052995A2 (en) Treatment and prevention of hepatocellular carcinoma with chemokine receptor modulators
JP2014517002A (ja) 損なわれた骨折治癒の処置のための標的及び薬剤

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20171030

FZDE Discontinued

Effective date: 20210831

FZDE Discontinued

Effective date: 20210831