CA2844270A1 - L-fabp based diagnosis of kidney injury after an acute event or after a surgical intervention - Google Patents

L-fabp based diagnosis of kidney injury after an acute event or after a surgical intervention Download PDF

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Publication number
CA2844270A1
CA2844270A1 CA2844270A CA2844270A CA2844270A1 CA 2844270 A1 CA2844270 A1 CA 2844270A1 CA 2844270 A CA2844270 A CA 2844270A CA 2844270 A CA2844270 A CA 2844270A CA 2844270 A1 CA2844270 A1 CA 2844270A1
Authority
CA
Canada
Prior art keywords
level
fabp
surgical intervention
individual
kidney injury
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2844270A
Other languages
English (en)
French (fr)
Inventor
Hendrik Huedig
Rosemarie Kientsch-Engel
Sandra RUTZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CMIC Holdings Co Ltd
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2844270A1 publication Critical patent/CA2844270A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CA2844270A 2011-09-07 2012-09-01 L-fabp based diagnosis of kidney injury after an acute event or after a surgical intervention Abandoned CA2844270A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11007260.0 2011-09-07
EP11007260A EP2568291A1 (en) 2011-09-07 2011-09-07 L-FABP based diagnosis of kidney injury after an acute event or after a surgical intervention
PCT/EP2012/003668 WO2013034264A1 (en) 2011-09-07 2012-09-01 L-fabp based diagnosis of kidney injury after an acute event or after a surgical intervention

Publications (1)

Publication Number Publication Date
CA2844270A1 true CA2844270A1 (en) 2013-03-14

Family

ID=46785363

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2844270A Abandoned CA2844270A1 (en) 2011-09-07 2012-09-01 L-fabp based diagnosis of kidney injury after an acute event or after a surgical intervention

Country Status (7)

Country Link
US (2) US20140187652A1 (ja)
EP (2) EP2568291A1 (ja)
JP (1) JP5931200B2 (ja)
CN (1) CN103946709B (ja)
CA (1) CA2844270A1 (ja)
HK (1) HK1200216A1 (ja)
WO (1) WO2013034264A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201214440D0 (en) * 2012-08-13 2012-09-26 Randox Lab Ltd Kidney disease biomarker
CN103941019A (zh) * 2014-04-10 2014-07-23 瑞莱生物工程（深圳）有限公司 快速定量检测l-fabp的免疫荧光试纸条及其制备方法
WO2016041069A1 (en) 2014-09-15 2016-03-24 Mcmaster University Method and panel for determining acute kidney injury
EP3243079B1 (en) * 2015-01-07 2022-11-02 Nottingham University Hospitals NHS Trust Biomarkers related to kidney function and methods involving their use
CN107533054A (zh) * 2015-02-25 2018-01-02 积水医疗株式会社 免疫测定方法以及用于所述方法的测定试剂
EP3264083B1 (en) * 2015-02-25 2019-09-25 Sekisui Medical Co., Ltd. L-fabp immunoassay method
JP6660934B2 (ja) * 2015-02-25 2020-03-11 積水メディカル株式会社 免疫学的測定方法及び該方法に用いられる測定試薬
US10598652B2 (en) 2015-04-09 2020-03-24 The Regents Of The University Of California Methods of diagnosing post-operative complications using serum nitric oxide levels
EP3334498B1 (en) 2015-08-12 2023-06-07 The Trustees of Columbia University in the City of New York Methods of treating volume depletion and kidney injury
KR102083104B1 (ko) 2015-10-08 2020-02-28 에프. 호프만-라 로슈 아게 수술 전 측정시 ａｋｉ 의 위험 예측을 위한 ｉｇｆｂｐ７
CN107677809A (zh) * 2017-08-24 2018-02-09 菲鹏生物股份有限公司 急性肾损伤的检测试剂盒
RU2702023C1 (ru) * 2018-08-17 2019-10-04 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ диагностики острого повреждения почек после органосохраняющего хирургического лечения локализованного рака почки

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
MXPA06004235A (es) 2003-10-15 2007-02-14 Daiichi Pure Chemicals Co Ltd Metodo de separar y ensayar multimero de adiponectina.
AU2005289088B2 (en) * 2004-09-29 2011-04-07 Cellartis Ab Methods for the generation of hepatocyte-like cells from human blastocyst-derived stem (hBS)
US8026345B2 (en) 2007-01-08 2011-09-27 Hoffmann-La Roche Inc. Characterization and identification of unique human adiponectin isoforms and antibodies
EP2042873A1 (en) * 2007-09-28 2009-04-01 Roche Diagnostics GmbH Means and methods for the detection of contrast medium-induced nephrotoxicity
WO2009081680A1 (ja) * 2007-12-21 2009-07-02 Konica Minolta Medical & Graphic, Inc. 腎症の検査方法及びそれを用いた検査キット
EP2261660B1 (en) * 2008-02-29 2013-08-07 National University Corporation Nagoya University Biomarker for the estimation of acute renal disorder and prognosis of the disorder, and use of the biomarker
US20090238812A1 (en) * 2008-03-18 2009-09-24 Biotrin Intellectual Properties Limited Method for the early indentification and prediction of an abrupt reduction in kidney function in a patient undergoing cardiothoracic surgery
KR101939964B1 (ko) * 2008-11-21 2019-01-18 퓨처 메디칼 다이아그노스틱스 코 엘티디 급성 신장 손상의 발견 또는 감시 방법, 장치 및 키트
WO2010125165A1 (en) * 2009-04-30 2010-11-04 Roche Diagnostics Gmbh Means and methods for diagnosing a heart failure associated kidney damage in individuals in need of a suitable therapy
EP2336784B1 (en) * 2009-12-18 2017-08-16 Roche Diagnostics GmbH GDF-15 and/or Troponin T for predicting kidney failure in heart surgery patients
AU2011220413B2 (en) * 2010-02-26 2015-07-23 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN102939541B (zh) * 2010-06-15 2015-12-02 弗·哈夫曼-拉罗切有限公司 手术后急性肾损伤的预测和识别

Also Published As

Publication number Publication date
JP2014526676A (ja) 2014-10-06
EP2753936A1 (en) 2014-07-16
CN103946709B (zh) 2016-04-27
JP5931200B2 (ja) 2016-06-08
US20140187652A1 (en) 2014-07-03
HK1200216A1 (zh) 2015-07-31
WO2013034264A1 (en) 2013-03-14
EP2568291A1 (en) 2013-03-13
CN103946709A (zh) 2014-07-23
US20160245827A1 (en) 2016-08-25

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20170830

FZDE Discontinued

Effective date: 20190904