CA2837322C - Cell and gene based methods to improve cardiac function - Google Patents

Cell and gene based methods to improve cardiac function Download PDF

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Publication number
CA2837322C
CA2837322C CA2837322A CA2837322A CA2837322C CA 2837322 C CA2837322 C CA 2837322C CA 2837322 A CA2837322 A CA 2837322A CA 2837322 A CA2837322 A CA 2837322A CA 2837322 C CA2837322 C CA 2837322C
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cardiac
nucleic acid
cardiomyocytes
acid sequence
ctnc
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French (fr)
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CA2837322A1 (en
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Michael REGNIER
Michael LAFLAMME
Charles MURRY
F. Steven Korte
Scott Lundy
Stephen Denison Hauschka
Jeffrey S. Chamberlain
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WASHINGTON, University of
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WASHINGTON, University of
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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CA2837322A 2011-05-26 2012-05-29 Cell and gene based methods to improve cardiac function Active CA2837322C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161490450P 2011-05-26 2011-05-26
US61/490,450 2011-05-26
PCT/US2012/039897 WO2012162705A2 (en) 2011-05-26 2012-05-29 Cell and gene based methods to improve cardiac function

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Publication Number Publication Date
CA2837322A1 CA2837322A1 (en) 2012-11-29
CA2837322C true CA2837322C (en) 2023-03-21

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CA2837322A Active CA2837322C (en) 2011-05-26 2012-05-29 Cell and gene based methods to improve cardiac function

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US (1) US9868937B2 (enExample)
EP (1) EP2714709B1 (enExample)
JP (1) JP6162104B2 (enExample)
KR (1) KR20140035967A (enExample)
CN (1) CN103946230B (enExample)
AU (1) AU2012258525B2 (enExample)
BR (1) BR112013030209A2 (enExample)
CA (1) CA2837322C (enExample)
RU (1) RU2608957C2 (enExample)
WO (1) WO2012162705A2 (enExample)

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CA2837322C (en) 2011-05-26 2023-03-21 University Of Washington Cell and gene based methods to improve cardiac function
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WO2015153357A1 (en) * 2014-03-29 2015-10-08 Beat Biotherapeutics Corp. Compositions and methods for improving cardiac function
WO2016115543A2 (en) * 2015-01-16 2016-07-21 University Of Washington Novel micro-dystrophins and related methods of use
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JP6940920B2 (ja) 2017-02-04 2021-09-29 アナバイオス コーポレーション 医薬誘発性の変力作用および不整脈誘発のリスクを予測するためのシステムおよび方法
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US20200405824A1 (en) * 2019-06-26 2020-12-31 University Of Washington Use of ribonucleotide reductase alone or in combination with micro-dystrophin to treat duchenne muscular dystrophy striated muscle disease
CN110384800B (zh) * 2019-07-19 2021-06-08 广东省实验动物监测所 LncRNA XLOC_075168在制备促进血管新生的药物中的应用
FI4103214T3 (fi) 2020-02-13 2026-07-03 Tenaya Therapeutics Inc Geeniterapian vektorit sydänsairauden hoitoon
US20240189481A1 (en) * 2021-04-06 2024-06-13 University Of Washington Non-contractile cardiomyocytes for cardiac repair
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WO2025207745A1 (en) * 2024-03-27 2025-10-02 The Board Of Trustees Of The Leland Stanford Junior University Methods of inducing dilated cardiomyopathy phenotype in cardiomyocytes and applications thereof
CN120758566B (zh) * 2025-09-10 2025-11-21 瓯江实验室 一种在心肌细胞中特异性过表达zer1的病毒载体的构建及在心衰治疗中的应用

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WO2012162705A3 (en) 2013-02-28
RU2608957C2 (ru) 2017-01-27
US20160186139A1 (en) 2016-06-30
US9868937B2 (en) 2018-01-16
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