CA2813900C - Methods of treating psoriasis using il-17 antagonists - Google Patents

Methods of treating psoriasis using il-17 antagonists Download PDF

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Publication number
CA2813900C
CA2813900C CA2813900A CA2813900A CA2813900C CA 2813900 C CA2813900 C CA 2813900C CA 2813900 A CA2813900 A CA 2813900A CA 2813900 A CA2813900 A CA 2813900A CA 2813900 C CA2813900 C CA 2813900C
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CA
Canada
Prior art keywords
antibody
seq
secukinumab
patient
psoriasis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2813900A
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English (en)
French (fr)
Other versions
CA2813900A1 (en
Inventor
Achim Guettner
Matthias Machacek
Charis Papavassilis
Oliver Sander
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Novartis AG
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Novartis AG
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44759699&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2813900(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of CA2813900A1 publication Critical patent/CA2813900A1/en
Application granted granted Critical
Publication of CA2813900C publication Critical patent/CA2813900C/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2813900A 2010-10-08 2011-10-07 Methods of treating psoriasis using il-17 antagonists Active CA2813900C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39138810P 2010-10-08 2010-10-08
US61/391,388 2010-10-08
PCT/EP2011/067522 WO2012045848A1 (en) 2010-10-08 2011-10-07 Methods of treating psoriasis using il-17 antagonists

Publications (2)

Publication Number Publication Date
CA2813900A1 CA2813900A1 (en) 2012-04-12
CA2813900C true CA2813900C (en) 2017-01-10

Family

ID=44759699

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2813900A Active CA2813900C (en) 2010-10-08 2011-10-07 Methods of treating psoriasis using il-17 antagonists

Country Status (28)

Country Link
US (9) US9717791B2 (https=)
EP (5) EP3299390A1 (https=)
JP (2) JP5537740B2 (https=)
KR (3) KR20130110179A (https=)
CN (2) CN103154031A (https=)
AU (1) AU2011311482B2 (https=)
BR (1) BR112013008501A2 (https=)
CA (1) CA2813900C (https=)
CL (1) CL2013000930A1 (https=)
CY (1) CY1119942T1 (https=)
DK (1) DK2625199T3 (https=)
ES (1) ES2660770T3 (https=)
HK (1) HK1247932A1 (https=)
HR (1) HRP20180301T1 (https=)
HU (1) HUE038334T2 (https=)
IL (1) IL225310A (https=)
LT (1) LT2625199T (https=)
MA (1) MA34646B1 (https=)
MX (1) MX356279B (https=)
NO (1) NO2625199T3 (https=)
PH (1) PH12013500660B1 (https=)
PL (1) PL2625199T3 (https=)
PT (1) PT2625199T (https=)
RU (2) RU2665954C1 (https=)
SG (1) SG188979A1 (https=)
SI (1) SI2625199T1 (https=)
TW (2) TWI564022B (https=)
WO (1) WO2012045848A1 (https=)

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AR103172A1 (es) 2014-12-22 2017-04-19 Novartis Ag Reducción selectiva de residuos de cisteina en anticuerpos il-17
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Also Published As

Publication number Publication date
PH12013500660B1 (en) 2017-10-27
US20250161445A1 (en) 2025-05-22
IL225310A (en) 2016-10-31
KR20150018595A (ko) 2015-02-23
BR112013008501A2 (pt) 2016-08-16
SI2625199T1 (en) 2018-03-30
MA34646B1 (fr) 2013-11-02
US11534490B2 (en) 2022-12-27
EP2625199A1 (en) 2013-08-14
HUE038334T2 (hu) 2018-10-29
CL2013000930A1 (es) 2014-03-28
SG188979A1 (en) 2013-05-31
CA2813900A1 (en) 2012-04-12
EP2625199B1 (en) 2017-11-22
TWI564022B (zh) 2017-01-01
US10583190B2 (en) 2020-03-10
IL225310A0 (en) 2013-06-27
HRP20180301T1 (hr) 2018-03-23
US20210113688A1 (en) 2021-04-22
KR101620771B1 (ko) 2016-05-12
EP4137514A1 (en) 2023-02-22
PH12013500660A1 (en) 2013-05-20
NO2625199T3 (https=) 2018-04-21
US20170304439A1 (en) 2017-10-26
US9717791B2 (en) 2017-08-01
MX356279B (es) 2018-05-22
TWI548419B (zh) 2016-09-11
US20130202610A1 (en) 2013-08-08
US12594331B2 (en) 2026-04-07
ES2660770T3 (es) 2018-03-26
JP2014114288A (ja) 2014-06-26
EP3299390A1 (en) 2018-03-28
CN103154031A (zh) 2013-06-12
EP4670788A3 (en) 2026-03-18
CN107029234A (zh) 2017-08-11
US12551554B2 (en) 2026-02-17
RU2591083C2 (ru) 2016-07-10
RU2665954C1 (ru) 2018-09-05
KR20130110179A (ko) 2013-10-08
TW201630625A (zh) 2016-09-01
DK2625199T3 (en) 2018-02-26
RU2013120957A (ru) 2014-11-20
JP2013543501A (ja) 2013-12-05
HK1247932A1 (en) 2018-10-05
PT2625199T (pt) 2018-02-28
US12594332B2 (en) 2026-04-07
LT2625199T (lt) 2018-03-12
PL2625199T3 (pl) 2018-04-30
EP3792281A1 (en) 2021-03-17
US20230321231A1 (en) 2023-10-12
US20200171147A1 (en) 2020-06-04
EP4670788A2 (en) 2025-12-31
AU2011311482A1 (en) 2013-04-04
CY1119942T1 (el) 2018-12-12
US20210162044A1 (en) 2021-06-03
TW201216984A (en) 2012-05-01
WO2012045848A1 (en) 2012-04-12
US20250161444A1 (en) 2025-05-22
JP5537740B2 (ja) 2014-07-02
AU2011311482B2 (en) 2014-05-29
US20250161443A1 (en) 2025-05-22
KR20140097566A (ko) 2014-08-06
MX2013003916A (es) 2013-06-03

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