CA2810573A1 - Apoptosis imaging agents based on lantibiotic peptides - Google Patents

Apoptosis imaging agents based on lantibiotic peptides Download PDF

Info

Publication number
CA2810573A1
CA2810573A1 CA2810573A CA2810573A CA2810573A1 CA 2810573 A1 CA2810573 A1 CA 2810573A1 CA 2810573 A CA2810573 A CA 2810573A CA 2810573 A CA2810573 A CA 2810573A CA 2810573 A1 CA2810573 A1 CA 2810573A1
Authority
CA
Canada
Prior art keywords
chelator
conjugate
imaging agent
lbp
imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2810573A
Other languages
English (en)
French (fr)
Inventor
Bard Indrevoll
Duncan Hiscock
Bente Elizabeth Arbo
Rajiv Bhalla
Matthias Eberhard Glaser
Graeme Walter Mcrobbie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of CA2810573A1 publication Critical patent/CA2810573A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA2810573A 2010-09-27 2011-09-27 Apoptosis imaging agents based on lantibiotic peptides Abandoned CA2810573A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1016206.3 2010-09-27
GBGB1016206.3A GB201016206D0 (en) 2010-09-27 2010-09-27 Apoptosis imaging agents
PCT/EP2011/066789 WO2012041862A1 (en) 2010-09-27 2011-09-27 Apoptosis imaging agents based on lantibiotic peptides

Publications (1)

Publication Number Publication Date
CA2810573A1 true CA2810573A1 (en) 2012-04-05

Family

ID=43128013

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2810573A Abandoned CA2810573A1 (en) 2010-09-27 2011-09-27 Apoptosis imaging agents based on lantibiotic peptides

Country Status (13)

Country Link
US (1) US20130189186A1 (enExample)
EP (1) EP2621545A1 (enExample)
JP (1) JP2013538819A (enExample)
KR (1) KR20130097780A (enExample)
CN (1) CN103118710A (enExample)
AU (1) AU2011310663A1 (enExample)
BR (1) BR112013006536A2 (enExample)
CA (1) CA2810573A1 (enExample)
GB (1) GB201016206D0 (enExample)
MX (1) MX2013003398A (enExample)
RU (1) RU2013113677A (enExample)
SG (1) SG188464A1 (enExample)
WO (1) WO2012041862A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108144073A (zh) * 2017-12-28 2018-06-12 中山大学附属第医院 靶向磷脂酰乙醇胺的放射性标记三聚乙二醇修饰耐久霉素多肽药物
GB201804835D0 (en) * 2018-03-26 2018-05-09 Ge Healthcare As Formulation and method of preparation
EP4057002B1 (en) 2019-11-12 2024-08-07 Ewha University-Industry Collaboration Foundation Cell imaging composition and cellular material imaging method using same
CN113368264B (zh) * 2020-03-09 2022-09-30 南方医科大学南方医院 放射性标记肉桂霉素，其制备方法及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0105224D0 (en) * 2001-03-02 2001-04-18 Nycomed Amersham Plc Improved peptide-chelate conjugates
US7034113B2 (en) * 2002-02-22 2006-04-25 Paradigm Diagnostics, Llc Bacteriocin-metal complexes in the detection of pathogens and other biological analytes
US7879801B2 (en) 2002-07-15 2011-02-01 Board Of Regents, The University Of Texas System Compositions comprising cell-impermeant duramycin derivatives
GB0416062D0 (en) * 2004-07-19 2004-08-18 Amersham Plc Improved N4 chelator conjugates
US20060110323A1 (en) 2004-11-19 2006-05-25 Ming Zhao Method of imaging cell death in vivo
AU2009223677A1 (en) 2008-03-10 2009-09-17 Mcw Research Foundation, Inc. 99mTc-labeled 19 amino acid containing peptide for use as phosphatidylethanolamine binding molecular probe and radiopharmaceutical

Also Published As

Publication number Publication date
SG188464A1 (en) 2013-04-30
US20130189186A1 (en) 2013-07-25
JP2013538819A (ja) 2013-10-17
MX2013003398A (es) 2013-05-30
KR20130097780A (ko) 2013-09-03
BR112013006536A2 (pt) 2016-05-31
AU2011310663A1 (en) 2013-03-28
EP2621545A1 (en) 2013-08-07
GB201016206D0 (en) 2010-11-10
WO2012041862A1 (en) 2012-04-05
RU2013113677A (ru) 2014-11-10
CN103118710A (zh) 2013-05-22

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20150929