CA2802868A1 - Methods and systems for generating, validating and using monoclonal antibodies - Google Patents
Methods and systems for generating, validating and using monoclonal antibodies Download PDFInfo
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Classifications
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- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
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- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
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- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| US35532910P | 2010-06-16 | 2010-06-16 | |
| US61/355,329 | 2010-06-16 | ||
| PCT/US2011/040789 WO2011159959A2 (en) | 2010-06-16 | 2011-06-16 | Methods and systems for generating, validating and using monoclonal antibodies |
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| CA2802868A1 true CA2802868A1 (en) | 2011-12-22 |
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| US20140051586A1 (en) * | 2011-01-25 | 2014-02-20 | Ignacio Pino | High-throughput methods to produce, validate and characterize mmabs |
| WO2014172345A2 (en) * | 2013-04-15 | 2014-10-23 | Massachusetts Institute Of Technology | Fully automated system and method for image segmentation and quality control of protein microarrays |
| US10208290B2 (en) * | 2013-06-21 | 2019-02-19 | The Johns Hopkins University | Virion display array for profiling functions and interactions of human membrane proteins |
| US20190391147A1 (en) * | 2016-04-07 | 2019-12-26 | Rowan University | Methods and kits for detecting myo/nog cells in human adipose tissue and methods of use thereof |
| CN109470852A (zh) * | 2018-12-07 | 2019-03-15 | 华南农业大学 | 一种母乳多克隆抗体免疫亲和柱及其制备方法 |
| WO2025101487A1 (en) * | 2023-11-06 | 2025-05-15 | Bruker Cellular Analysis, Inc. | Affinity assay for microfluidic devices |
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| DE4134297A1 (de) * | 1991-10-17 | 1993-04-22 | Behringwerke Ag | Monoclonale antikoerper gegen mycoplasma pneumoniae, diese produzierende hybridome, verfahren zu deren herstellung sowie deren verwendung |
| CA2319828A1 (en) * | 1998-01-29 | 1999-08-05 | Miller, Samuel | High density arrays for proteome analysis and methods and compositions therefor |
| US6794132B2 (en) * | 1999-10-02 | 2004-09-21 | Biosite, Inc. | Human antibodies |
| EP1572971B1 (en) * | 2002-11-15 | 2009-09-30 | Morphotek Inc. | Methods of generating high-production of antibodies from hybridomas created by in vitro immunization |
| US20060223131A1 (en) * | 2004-09-15 | 2006-10-05 | Barry Schweitzer | Protein arrays and methods of use thereof |
| ATE553385T1 (de) * | 2004-10-23 | 2012-04-15 | Biosystems Technology Corp | Plattformtechnologie zur expressionsprofilierung |
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| US20070003954A1 (en) * | 2005-05-12 | 2007-01-04 | The Board Of Regents Of The University Of Texas System | Protein and antibody profiling using small molecule microarrays |
| CN1786298A (zh) * | 2005-10-28 | 2006-06-14 | 上海博昂抗体生物科技有限公司 | 抗细胞或组织蛋白质单克隆抗体库的制备方法 |
| EP1921142A1 (en) * | 2006-11-07 | 2008-05-14 | Cytos Biotechnology AG | Selection of human monoclonal antibodies by eukaryotic cell display |
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- 2011-06-16 US US13/704,592 patent/US20130288910A1/en not_active Abandoned
- 2011-06-16 JP JP2013515529A patent/JP2013533865A/ja not_active Withdrawn
- 2011-06-16 CA CA2802868A patent/CA2802868A1/en not_active Abandoned
-
2016
- 2016-10-03 JP JP2016195881A patent/JP2016222725A/ja active Pending
-
2017
- 2017-06-23 US US15/632,261 patent/US20180030086A1/en not_active Abandoned
-
2022
- 2022-06-06 US US17/833,001 patent/US20220363712A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2582862B1 (en) | 2016-04-13 |
| WO2011159959A3 (en) | 2013-03-28 |
| CN103168119B (zh) | 2016-05-11 |
| US20130288910A1 (en) | 2013-10-31 |
| CN103168119A (zh) | 2013-06-19 |
| WO2011159959A2 (en) | 2011-12-22 |
| US20180030086A1 (en) | 2018-02-01 |
| HK1182745A1 (zh) | 2013-12-06 |
| US20220363712A1 (en) | 2022-11-17 |
| JP2016222725A (ja) | 2016-12-28 |
| EP2582862A2 (en) | 2013-04-24 |
| EP2582862A4 (en) | 2014-01-15 |
| JP2013533865A (ja) | 2013-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20160615 |
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| FZDE | Discontinued |
Effective date: 20181029 |