HK1182745A1 - 用於產生、確認和使用單克隆抗體的方法和系統 - Google Patents

用於產生、確認和使用單克隆抗體的方法和系統

Info

Publication number
HK1182745A1
HK1182745A1 HK13110091.2A HK13110091A HK1182745A1 HK 1182745 A1 HK1182745 A1 HK 1182745A1 HK 13110091 A HK13110091 A HK 13110091A HK 1182745 A1 HK1182745 A1 HK 1182745A1
Authority
HK
Hong Kong
Prior art keywords
validating
generating
systems
methods
monoclonal antibodies
Prior art date
Application number
HK13110091.2A
Other languages
English (en)
Inventor
傑夫．
．伯克
恒．朱
塞斯．布萊克肖
丹尼爾．
．艾興格
伊格納西奧．皮諾
Original Assignee
約翰．霍普金斯大學
實驗室公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 約翰．霍普金斯大學, 實驗室公司 filed Critical 約翰．霍普金斯大學
Publication of HK1182745A1 publication Critical patent/HK1182745A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
HK13110091.2A 2010-06-16 2013-08-28 用於產生、確認和使用單克隆抗體的方法和系統 HK1182745A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35532910P 2010-06-16 2010-06-16
PCT/US2011/040789 WO2011159959A2 (en) 2010-06-16 2011-06-16 Methods and systems for generating, validating and using monoclonal antibodies

Publications (1)

Publication Number Publication Date
HK1182745A1 true HK1182745A1 (zh) 2013-12-06

Family

ID=45348882

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13110091.2A HK1182745A1 (zh) 2010-06-16 2013-08-28 用於產生、確認和使用單克隆抗體的方法和系統

Country Status (7)

Country Link
US (3) US20130288910A1 (zh)
EP (1) EP2582862B1 (zh)
JP (2) JP2013533865A (zh)
CN (1) CN103168119B (zh)
CA (1) CA2802868A1 (zh)
HK (1) HK1182745A1 (zh)
WO (1) WO2011159959A2 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012103260A2 (en) * 2011-01-25 2012-08-02 Cdi Laboratories High-throughput methods to produce, validate and characterize mmabs
US20140307931A1 (en) * 2013-04-15 2014-10-16 Massachusetts Institute Of Technology Fully automated system and method for image segmentation and quality control of protein microarrays
JP6715766B2 (ja) * 2013-06-21 2020-07-01 ザ ジョンズ ホプキンス ユニバーシティ ヒト膜蛋白質の機能および相互作用をプロファイリングするためのビリオンディスプレイアレイ
WO2017177140A1 (en) * 2016-04-07 2017-10-12 Rowan University Methods and kits for detecting myo/nog cells in human adipose tissue and methods of use thereof
CN109470852A (zh) * 2018-12-07 2019-03-15 华南农业大学 一种母乳多克隆抗体免疫亲和柱及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4134297A1 (de) * 1991-10-17 1993-04-22 Behringwerke Ag Monoclonale antikoerper gegen mycoplasma pneumoniae, diese produzierende hybridome, verfahren zu deren herstellung sowie deren verwendung
CA2319828A1 (en) * 1998-01-29 1999-08-05 Miller, Samuel High density arrays for proteome analysis and methods and compositions therefor
US6794132B2 (en) * 1999-10-02 2004-09-21 Biosite, Inc. Human antibodies
WO2004046330A2 (en) * 2002-11-15 2004-06-03 Morphotek, Inc. Methods of generating high-production of antibodies from hybridomas created by in vitro immunization
WO2006033972A2 (en) * 2004-09-15 2006-03-30 Protometrix, Inc. Protein arrays and methods of use thereof
US20070293437A1 (en) * 2004-10-23 2007-12-20 Andras Guttman Expression Profiling Platform Technology
MX2007006441A (es) * 2004-11-30 2007-08-14 Johnson & Johnson Prognosis de cancer de pulmon.
US20070003954A1 (en) * 2005-05-12 2007-01-04 The Board Of Regents Of The University Of Texas System Protein and antibody profiling using small molecule microarrays
CN1786298A (zh) * 2005-10-28 2006-06-14 上海博昂抗体生物科技有限公司 抗细胞或组织蛋白质单克隆抗体库的制备方法
EP1921142A1 (en) * 2006-11-07 2008-05-14 Cytos Biotechnology AG Selection of human monoclonal antibodies by eukaryotic cell display
WO2009108170A2 (en) * 2007-11-16 2009-09-03 Invitrogen Corporation Compositions and methods for determining immune status
CA2731797A1 (en) * 2008-07-25 2010-01-28 Theraclone Sciences Methods and compositions for discovery of target-specific antibodies using antibody repertoire array (ara)
CA2774615A1 (en) * 2009-09-25 2011-03-31 Origene Technologies, Inc. Protein arrays and uses thereof

Also Published As

Publication number Publication date
US20130288910A1 (en) 2013-10-31
CN103168119B (zh) 2016-05-11
WO2011159959A3 (en) 2013-03-28
EP2582862A2 (en) 2013-04-24
WO2011159959A2 (en) 2011-12-22
CA2802868A1 (en) 2011-12-22
EP2582862B1 (en) 2016-04-13
EP2582862A4 (en) 2014-01-15
JP2013533865A (ja) 2013-08-29
US20180030086A1 (en) 2018-02-01
JP2016222725A (ja) 2016-12-28
CN103168119A (zh) 2013-06-19
US20220363712A1 (en) 2022-11-17

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