CA2793389A1 - Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers - Google Patents

Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers Download PDF

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Publication number
CA2793389A1
CA2793389A1 CA2793389A CA2793389A CA2793389A1 CA 2793389 A1 CA2793389 A1 CA 2793389A1 CA 2793389 A CA2793389 A CA 2793389A CA 2793389 A CA2793389 A CA 2793389A CA 2793389 A1 CA2793389 A1 CA 2793389A1
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Canada
Prior art keywords
cancer
seq
peptides
peptide
cell
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2793389A
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English (en)
French (fr)
Inventor
Jens Fritsche
Toni Weinschenk
Steffen Walter
Peter Lewandrowski
Harpreet Singh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immatics Biotechnologies GmbH
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Immatics Biotechnologies GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immatics Biotechnologies GmbH filed Critical Immatics Biotechnologies GmbH
Publication of CA2793389A1 publication Critical patent/CA2793389A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/828Stomach
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
CA2793389A 2010-03-19 2011-03-16 Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers Abandoned CA2793389A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US31571510P 2010-03-19 2010-03-19
US61/315,715 2010-03-19
GB1004575.5 2010-03-19
GB201004575A GB201004575D0 (en) 2010-03-19 2010-03-19 Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers
PCT/EP2011/053996 WO2011113872A1 (en) 2010-03-19 2011-03-16 Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers

Publications (1)

Publication Number Publication Date
CA2793389A1 true CA2793389A1 (en) 2011-09-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2793389A Abandoned CA2793389A1 (en) 2010-03-19 2011-03-16 Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers

Country Status (21)

Country Link
US (2) US10159725B2 (enExample)
EP (1) EP2547691B1 (enExample)
JP (1) JP5689140B2 (enExample)
KR (1) KR101620132B1 (enExample)
CN (1) CN102892777B (enExample)
AU (1) AU2011229177B2 (enExample)
BR (1) BR112012023621A2 (enExample)
CA (1) CA2793389A1 (enExample)
EA (1) EA022743B1 (enExample)
ES (1) ES2593409T3 (enExample)
GB (1) GB201004575D0 (enExample)
HU (1) HUE030000T2 (enExample)
MX (1) MX2012010814A (enExample)
MY (1) MY162850A (enExample)
NZ (1) NZ601818A (enExample)
PH (1) PH12012501822A1 (enExample)
PL (1) PL2547691T3 (enExample)
SG (1) SG183938A1 (enExample)
TW (1) TWI533882B (enExample)
UA (1) UA109891C2 (enExample)
WO (1) WO2011113872A1 (enExample)

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Publication number Publication date
PL2547691T3 (pl) 2016-12-30
HK1180701A1 (zh) 2013-10-25
KR101620132B1 (ko) 2016-05-12
EP2547691A1 (en) 2013-01-23
KR20130057428A (ko) 2013-05-31
WO2011113872A1 (en) 2011-09-22
JP5689140B2 (ja) 2015-03-25
US20130115188A1 (en) 2013-05-09
EP2547691B1 (en) 2016-06-29
GB201004575D0 (en) 2010-05-05
NZ601818A (en) 2014-09-26
UA109891C2 (uk) 2015-10-26
AU2011229177B2 (en) 2014-09-25
US20110229524A1 (en) 2011-09-22
US9132177B2 (en) 2015-09-15
ES2593409T3 (es) 2016-12-09
CN102892777A (zh) 2013-01-23
TW201201834A (en) 2012-01-16
BR112012023621A2 (pt) 2017-07-18
CN102892777B (zh) 2017-02-08
TWI533882B (zh) 2016-05-21
SG183938A1 (en) 2012-10-30
US10159725B2 (en) 2018-12-25
AU2011229177A1 (en) 2012-09-06
EA022743B1 (ru) 2016-02-29
EA201201305A1 (ru) 2013-02-28
MX2012010814A (es) 2012-11-12
HUE030000T2 (en) 2017-04-28
JP2013522276A (ja) 2013-06-13
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