CA2788993A1 - Peptides capables de se lier a la serumalbumine, et composes, constructions, et polypeptides comprenant de tels peptides - Google Patents

Peptides capables de se lier a la serumalbumine, et composes, constructions, et polypeptides comprenant de tels peptides Download PDF

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Publication number
CA2788993A1
CA2788993A1 CA2788993A CA2788993A CA2788993A1 CA 2788993 A1 CA2788993 A1 CA 2788993A1 CA 2788993 A CA2788993 A CA 2788993A CA 2788993 A CA2788993 A CA 2788993A CA 2788993 A1 CA2788993 A1 CA 2788993A1
Authority
CA
Canada
Prior art keywords
amino acid
seq
acid sequence
sequence
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2788993A
Other languages
English (en)
Inventor
Hilde Adi Pierrette Revets
Carlo Boutton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ablynx NV
Original Assignee
Ablynx NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ablynx NV filed Critical Ablynx NV
Publication of CA2788993A1 publication Critical patent/CA2788993A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
CA2788993A 2010-02-05 2011-02-03 Peptides capables de se lier a la serumalbumine, et composes, constructions, et polypeptides comprenant de tels peptides Abandoned CA2788993A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30181910P 2010-02-05 2010-02-05
US61/301,819 2010-02-05
PCT/EP2011/051559 WO2011095545A1 (fr) 2010-02-05 2011-02-03 Peptides capables de se lier à la sérumalbumine, et composés, constructions, et polypeptides comprenant de tels peptides

Publications (1)

Publication Number Publication Date
CA2788993A1 true CA2788993A1 (fr) 2011-08-11

Family

ID=44233823

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2788993A Abandoned CA2788993A1 (fr) 2010-02-05 2011-02-03 Peptides capables de se lier a la serumalbumine, et composes, constructions, et polypeptides comprenant de tels peptides

Country Status (6)

Country Link
EP (1) EP2531523A1 (fr)
JP (1) JP2013518853A (fr)
CN (1) CN102781959A (fr)
AU (1) AU2011212442A1 (fr)
CA (1) CA2788993A1 (fr)
WO (1) WO2011095545A1 (fr)

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JP7163028B2 (ja) 2015-05-13 2022-10-31 アブリンクス エン．ヴェー． Ｃｄ３反応性に基づくｔ細胞リクルートポリペプチド
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JP7222888B2 (ja) 2016-11-16 2023-02-15 アブリンクス エン．ヴェー． Ｃｄ１２３及びｔｃｒアルファ／ベータに結合することが可能なｔ細胞動員ポリペプチド
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BR112019028269A2 (pt) * 2017-07-11 2020-07-14 Alexion Pharmaceuticals, Inc. polipeptídeos que se ligam ao componente c5 do complemento ou à albumina sérica e suas proteínas de fusão
CN109608518B (zh) * 2018-11-06 2022-04-29 南阳师范学院 一种五肽及其应用
WO2022098745A1 (fr) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, systèmes d'administration et méthodes utiles dans la thérapie antitumorale
WO2022098743A1 (fr) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, imagerie et procédés thérapeutiques ciblant le récepteur 1 de folate (folr1)
WO2022166720A1 (fr) * 2021-02-05 2022-08-11 华南理工大学 Protéine de fusion à base d'albumine sérique, et nano-ensemble, son procédé de préparation et son application
WO2023121999A1 (fr) 2021-12-23 2023-06-29 Fresenius Medical Care Holdings, Inc. Composés, systèmes et techniques d'élimination de peptide bêta-amyloïde périphérique au moyen de compétiteurs de liaison à l'albumine

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Also Published As

Publication number Publication date
JP2013518853A (ja) 2013-05-23
WO2011095545A1 (fr) 2011-08-11
CN102781959A (zh) 2012-11-14
AU2011212442A1 (en) 2012-08-09
EP2531523A1 (fr) 2012-12-12

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Legal Events

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FZDE Discontinued

Effective date: 20140204