CA2777798A1 - Device and method for delivering medicine into the tympanic cavity - Google Patents
Device and method for delivering medicine into the tympanic cavity Download PDFInfo
- Publication number
- CA2777798A1 CA2777798A1 CA2777798A CA2777798A CA2777798A1 CA 2777798 A1 CA2777798 A1 CA 2777798A1 CA 2777798 A CA2777798 A CA 2777798A CA 2777798 A CA2777798 A CA 2777798A CA 2777798 A1 CA2777798 A1 CA 2777798A1
- Authority
- CA
- Canada
- Prior art keywords
- tympanic cavity
- extraction
- piercing element
- housing
- substance delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 210000000959 ear middle Anatomy 0.000 title claims abstract description 83
- 239000003814 drug Substances 0.000 title claims description 48
- 238000000034 method Methods 0.000 title claims description 21
- 210000003454 tympanic membrane Anatomy 0.000 claims abstract description 70
- 239000000126 substance Substances 0.000 claims abstract 42
- 238000000605 extraction Methods 0.000 claims abstract 34
- 210000000613 ear canal Anatomy 0.000 claims description 42
- 239000012530 fluid Substances 0.000 claims description 38
- 239000012528 membrane Substances 0.000 claims description 15
- 239000000853 adhesive Substances 0.000 claims description 10
- 230000001070 adhesive effect Effects 0.000 claims description 10
- 238000001574 biopsy Methods 0.000 claims description 9
- 229940079593 drug Drugs 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 3
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 230000000903 blocking effect Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000002775 capsule Substances 0.000 description 24
- 210000004379 membrane Anatomy 0.000 description 13
- 230000007246 mechanism Effects 0.000 description 12
- 239000000463 material Substances 0.000 description 10
- 238000007789 sealing Methods 0.000 description 9
- 230000035515 penetration Effects 0.000 description 8
- 210000003027 ear inner Anatomy 0.000 description 6
- 239000004033 plastic Substances 0.000 description 6
- 229920003023 plastic Polymers 0.000 description 6
- 230000006870 function Effects 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 229920001971 elastomer Polymers 0.000 description 4
- 230000009467 reduction Effects 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 230000036541 health Effects 0.000 description 3
- 208000022760 infectious otitis media Diseases 0.000 description 3
- 229920001084 poly(chloroprene) Polymers 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 210000001715 carotid artery Anatomy 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000036407 pain Effects 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 241000878128 Malleus Species 0.000 description 1
- 206010033078 Otitis media Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 description 1
- 229960003022 amoxicillin Drugs 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940124599 anti-inflammatory drug Drugs 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 229960003957 dexamethasone Drugs 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 210000000883 ear external Anatomy 0.000 description 1
- 210000000256 facial nerve Anatomy 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000010370 hearing loss Effects 0.000 description 1
- 231100000888 hearing loss Toxicity 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 210000001785 incus Anatomy 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000004731 jugular vein Anatomy 0.000 description 1
- 210000002331 malleus Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 208000037974 severe injury Diseases 0.000 description 1
- 230000009528 severe injury Effects 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 210000001050 stape Anatomy 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/84—Drainage tubes; Aspiration tips
- A61M1/87—Details of the aspiration tip, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/80—Suction pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M3/00—Medical syringes, e.g. enemata; Irrigators
- A61M3/02—Enemata; Irrigators
- A61M3/0279—Cannula; Nozzles; Tips; their connection means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0662—Ears
- A61M2210/0668—Middle ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Psychology (AREA)
- Prostheses (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25179209P | 2009-10-15 | 2009-10-15 | |
| US61/251,792 | 2009-10-15 | ||
| PCT/US2010/052569 WO2011047100A2 (en) | 2009-10-15 | 2010-10-13 | Device and method for delivering medicine into the tympanic cavity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2777798A1 true CA2777798A1 (en) | 2011-04-21 |
Family
ID=43876855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2777798A Abandoned CA2777798A1 (en) | 2009-10-15 | 2010-10-13 | Device and method for delivering medicine into the tympanic cavity |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20120203200A1 (enExample) |
| EP (1) | EP2488238A2 (enExample) |
| CN (1) | CN102791322A (enExample) |
| CA (1) | CA2777798A1 (enExample) |
| IN (1) | IN2012DN03426A (enExample) |
| WO (1) | WO2011047100A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120253267A1 (en) * | 2004-05-24 | 2012-10-04 | Reed Don C | Combined otic and medication dispenser and method for treating otic infections |
| WO2011115936A1 (en) * | 2010-03-15 | 2011-09-22 | Lev Rosenblum | Device and method for delivering medicine into the tympanic cavity, with sliding assist |
| WO2013113022A1 (en) * | 2012-01-29 | 2013-08-01 | Entra Tympanic, Llc | Device and method for the insertion and removal of tympanostomy tubes |
| DE102012223691A1 (de) * | 2012-12-19 | 2014-06-26 | Heine Optotechnik Gmbh & Co Kg | Otoskop mit abwerfbarem Ohrtrichter |
| US11730894B2 (en) * | 2017-07-21 | 2023-08-22 | Min Bo SHIM | Tip for intra-tympanic injection |
| US11806493B2 (en) * | 2018-02-02 | 2023-11-07 | Tusker Medical, Inc. | Systems, apparatus, and methods for transport and delivery of therapeutic substance to middle ear |
| CN114641266B (zh) * | 2019-11-01 | 2025-11-04 | 阿文塔米德指定活动公司 | 一种鼓膜治疗装置 |
| CN115426990A (zh) | 2020-01-24 | 2022-12-02 | 斯皮拉尔诊疗有限公司 | 通过鼓膜进入中耳和内耳的微创工具和方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1685984A (en) * | 1925-03-17 | 1928-10-02 | Cournand Jules | Syringe |
| DE3321621A1 (de) * | 1983-06-15 | 1984-12-20 | ANGIOMED GmbH Instrumente für die medizinische Diagnostik, 7505 Ettlingen | Vorrichtung zum punktieren von gewebe |
| US7351246B2 (en) * | 2004-01-20 | 2008-04-01 | Epley John M | Minimally invasive, sustained, intra-tympanic drug delivery system |
| CA2568028A1 (en) * | 2004-05-24 | 2005-12-08 | Auris Medical, Llc. | Combined otic aspirator and medication dispenser |
| US8115934B2 (en) * | 2008-01-18 | 2012-02-14 | The Board Of Trustees Of The University Of Illinois | Device and method for imaging the ear using optical coherence tomography |
-
2010
- 2010-10-13 WO PCT/US2010/052569 patent/WO2011047100A2/en not_active Ceased
- 2010-10-13 IN IN3426DEN2012 patent/IN2012DN03426A/en unknown
- 2010-10-13 CN CN2010800564042A patent/CN102791322A/zh active Pending
- 2010-10-13 US US13/501,073 patent/US20120203200A1/en not_active Abandoned
- 2010-10-13 CA CA2777798A patent/CA2777798A1/en not_active Abandoned
- 2010-10-13 EP EP10824060A patent/EP2488238A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011047100A9 (en) | 2012-05-18 |
| EP2488238A2 (en) | 2012-08-22 |
| IN2012DN03426A (enExample) | 2015-10-23 |
| WO2011047100A2 (en) | 2011-04-21 |
| CN102791322A (zh) | 2012-11-21 |
| US20120203200A1 (en) | 2012-08-09 |
| WO2011047100A3 (en) | 2012-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20151014 |