CA2775151C - Nouveaux polynucleotides et polypeptides chimeriques permettant la secretion d'un polypeptide d'interet en association avec des exosomes et leurs utilisations - Google Patents
Nouveaux polynucleotides et polypeptides chimeriques permettant la secretion d'un polypeptide d'interet en association avec des exosomes et leurs utilisations Download PDFInfo
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- CA2775151C CA2775151C CA2775151A CA2775151A CA2775151C CA 2775151 C CA2775151 C CA 2775151C CA 2775151 A CA2775151 A CA 2775151A CA 2775151 A CA2775151 A CA 2775151A CA 2775151 C CA2775151 C CA 2775151C
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- 229910052720 vanadium Inorganic materials 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
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- 210000000605 viral structure Anatomy 0.000 description 1
- 210000002845 virion Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 239000011534 wash buffer Substances 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 229940051021 yellow-fever virus Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
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- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
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- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR09/04576 | 2009-09-24 | ||
| FR0904576A FR2950350B1 (fr) | 2009-09-24 | 2009-09-24 | Nouveaux polynucleotides et polypeptides chimeriques permettant la secretion d'un polypeptide d'interet en association avec des exosomes et leurs utilisations |
| PCT/FR2010/052006 WO2011036416A1 (fr) | 2009-09-24 | 2010-09-23 | Nouveaux polynucleotides et polypeptides chimeriques permettant la secretion d'un polypeptide d'interet en association avec des exosomes et leurs utilisations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2775151A1 CA2775151A1 (fr) | 2011-03-31 |
| CA2775151C true CA2775151C (fr) | 2019-01-22 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2775151A Active CA2775151C (fr) | 2009-09-24 | 2010-09-23 | Nouveaux polynucleotides et polypeptides chimeriques permettant la secretion d'un polypeptide d'interet en association avec des exosomes et leurs utilisations |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9611481B2 (enExample) |
| EP (1) | EP2480672B8 (enExample) |
| JP (1) | JP5932647B2 (enExample) |
| CA (1) | CA2775151C (enExample) |
| FR (1) | FR2950350B1 (enExample) |
| WO (1) | WO2011036416A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2970984A1 (en) * | 2013-03-15 | 2016-01-20 | Novavax, Inc. | Enhanced expression of picornavirus proteins |
| US10538570B2 (en) * | 2013-09-30 | 2020-01-21 | Northwestern University | Targeted and modular exosome loading system |
| PL228341B1 (pl) * | 2014-04-21 | 2018-03-30 | Bio Ventures Inst Spolka Z Ograniczona Odpowiedzialnoscia | Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu |
| WO2016138525A1 (en) * | 2015-02-27 | 2016-09-01 | University Of Washington | Polypeptide assemblies and methods for the production thereof |
| US10702581B2 (en) | 2015-05-04 | 2020-07-07 | Ilias Biologics Inc. | Compositions containing protein loaded exosome and methods for preparing and delivering the same |
| WO2018062973A1 (en) * | 2016-09-30 | 2018-04-05 | Cellex Life Sciences, Incorporated | Compositions containing protein loaded exosome and methods for preparing and delivering the same |
| SMT202200156T1 (it) | 2018-11-16 | 2022-05-12 | Codiak Biosciences Inc | Vescicole extracellulari ingegnerizzate e loro usi |
| IT201900000651A1 (it) | 2019-01-16 | 2019-04-16 | Pastore Lucio | Tecnologia di trasferimento genico |
| JP2022525924A (ja) | 2019-03-21 | 2022-05-20 | コディアック バイオサイエンシーズ， インコーポレイテッド | 細胞外小胞コンジュゲート及びその使用 |
| KR20220009389A (ko) | 2019-04-17 | 2022-01-24 | 코디악 바이오사이언시즈, 인크. | 엑소좀 및 aav 의 조성물 |
| CN114173807B (zh) * | 2019-09-02 | 2024-03-19 | 庆北大学校产学协力团 | 包含il-2表面表达-细胞外囊泡作为活性成分的用于预防或治疗癌症的组合物 |
| WO2021144363A1 (en) | 2020-01-14 | 2021-07-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antigenic reactivity of a peptide mimicking the glycan loop of flaviviruses envelope protein |
| US20230097907A1 (en) * | 2020-01-27 | 2023-03-30 | Mantra Bio, Inc. | Non-naturally occurring vesicles comprising a chimeric vesicle localization moiety, methods of making and uses thereof |
| AU2021215935A1 (en) | 2020-02-05 | 2022-08-25 | Diadem Biotherapeutics Inc. | Artificial synapses |
| WO2021184021A1 (en) | 2020-03-13 | 2021-09-16 | Codiak Biosciences, Inc. | Extracellular vesicle-aso constructs targeting pmp22 |
| US20230302083A1 (en) * | 2020-04-20 | 2023-09-28 | The General Hospital Corporation | Highly-networked coronavirus immunogen composition |
| WO2021237100A1 (en) | 2020-05-21 | 2021-11-25 | Codiak Biosciences, Inc. | Methods of targeting extracellular vesicles to lung |
| US20230295229A1 (en) * | 2020-08-11 | 2023-09-21 | Kyungpook National University Industry-Academic Cooperation Foundation | Peptide selectively binding to cancer cell-derived exosome, and uses thereof |
| EP3973985A1 (en) * | 2020-09-29 | 2022-03-30 | Ciloa | Extracellular vesicles harboring a spike protein, nucleic acids for producing the same, and method of immunizing a subject against sars-cov-2 using the same |
| CN113480666B (zh) * | 2021-08-13 | 2024-01-26 | 郑州伊美诺生物技术有限公司 | Ca153融合蛋白及其制备方法和ca153检测质控品或校准品 |
| US20250312464A1 (en) | 2022-05-20 | 2025-10-09 | Ciloa | Reversible loading of proteins in the lumen of extracellular vesicles |
| WO2024097893A2 (en) * | 2022-11-02 | 2024-05-10 | Pioneer Biolabs, Llc | Systems and methods for single cell detection of protein secretion |
| WO2024251819A1 (en) * | 2023-06-05 | 2024-12-12 | Ciloa | Chimeric polypeptides, extracellular vesicles comprising the same, and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1417229B1 (en) * | 2001-08-17 | 2011-06-15 | Exothera L.L.C. | Methods and compounds for the targeting of protein to exosomes |
| CA2479021A1 (en) | 2002-03-14 | 2003-09-18 | Anosys, Inc. | Functionalization of t cell derived vesicles and use thereof for the preparation of immunogenic pharmaceutical compositions |
| US7914792B2 (en) * | 2003-02-14 | 2011-03-29 | Exothera L.L.C. | Methods and compounds for raising antibodies and for screening antibody repertoires |
| FR2928926B1 (fr) * | 2008-03-18 | 2015-08-21 | Centre Nat Rech Scient | Polynucleotides et polypeptides chimeriques permettant la secretion d'un polypeptide d'interet en association avec des exosomes et leur utilisation pour la production de compositions immunogenes |
-
2009
- 2009-09-24 FR FR0904576A patent/FR2950350B1/fr active Active
-
2010
- 2010-09-23 CA CA2775151A patent/CA2775151C/fr active Active
- 2010-09-23 WO PCT/FR2010/052006 patent/WO2011036416A1/fr not_active Ceased
- 2010-09-23 EP EP10769025.7A patent/EP2480672B8/fr active Active
- 2010-09-23 JP JP2012530319A patent/JP5932647B2/ja active Active
- 2010-09-23 US US13/497,779 patent/US9611481B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011036416A1 (fr) | 2011-03-31 |
| EP2480672B8 (fr) | 2017-03-22 |
| FR2950350A1 (fr) | 2011-03-25 |
| JP2013505713A (ja) | 2013-02-21 |
| JP5932647B2 (ja) | 2016-06-08 |
| US20120321653A1 (en) | 2012-12-20 |
| FR2950350B1 (fr) | 2013-12-13 |
| CA2775151A1 (fr) | 2011-03-31 |
| EP2480672B1 (fr) | 2016-12-28 |
| US9611481B2 (en) | 2017-04-04 |
| EP2480672A1 (fr) | 2012-08-01 |
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| EEER | Examination request |
Effective date: 20150825 |