CA2770241C - Method and probes to detect nucleic acid differences - Google Patents
Method and probes to detect nucleic acid differences Download PDFInfo
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- CA2770241C CA2770241C CA2770241A CA2770241A CA2770241C CA 2770241 C CA2770241 C CA 2770241C CA 2770241 A CA2770241 A CA 2770241A CA 2770241 A CA2770241 A CA 2770241A CA 2770241 C CA2770241 C CA 2770241C
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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| AU2012242847B2 (en) | 2011-04-15 | 2017-01-19 | The Johns Hopkins University | Safe sequencing system |
| KR20210056458A (ko) * | 2011-05-04 | 2021-05-18 | 바이오셉트 인코포레이티드 | 핵산 서열 변이체를 검출하는 방법 |
| WO2013039228A1 (ja) * | 2011-09-14 | 2013-03-21 | 日本碍子株式会社 | 標的核酸の検出方法 |
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| EP2824180B1 (en) * | 2012-03-05 | 2019-04-03 | NGK Insulators, Ltd. | Method for detecting target nucleic acid |
| EP2912468B1 (en) | 2012-10-29 | 2018-09-12 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
| US9637791B2 (en) * | 2013-12-20 | 2017-05-02 | Roche Molecular Systems, Inc. | Multiplexed nucleic acid target identification by strucutre based probe cleavage |
| WO2016098595A1 (ja) * | 2014-12-19 | 2016-06-23 | 栄研化学株式会社 | 一塩基多型検出用オリゴヌクレオチドプローブ及び一塩基多型検出方法 |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| JP2018526009A (ja) * | 2015-09-03 | 2018-09-13 | ナノストリング テクノロジーズ，インコーポレイティド | ヌクレオチド１個の分解能を有する多価プローブ |
| US20190211377A1 (en) * | 2016-12-22 | 2019-07-11 | Roche Molecular Systems, Inc. | Cobra probes to detect a marker for epidemic ribotypes of clostridium difficile |
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| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| DE3529478A1 (de) | 1985-08-16 | 1987-02-19 | Boehringer Mannheim Gmbh | 7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung |
| US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
| US5994069A (en) * | 1996-01-24 | 1999-11-30 | Third Wave Technologies, Inc. | Detection of nucleic acids by multiple sequential invasive cleavages |
| US5484908A (en) | 1991-11-26 | 1996-01-16 | Gilead Sciences, Inc. | Oligonucleotides containing 5-propynyl pyrimidines |
| TW393513B (en) | 1991-11-26 | 2000-06-11 | Isis Pharmaceuticals Inc | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
| DE637965T1 (de) | 1991-11-26 | 1995-12-14 | Gilead Sciences Inc | Gesteigerte bildung von triple- und doppelhelices aus oligomeren mit modifizierten pyrimidinen. |
| US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
| US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| ATE280177T1 (de) | 1997-03-20 | 2004-11-15 | Hoffmann La Roche | Modifizierte primer |
| JP2002510465A (ja) * | 1998-01-27 | 2002-04-09 | サイトセル・リミテッド | 修飾核酸プローブおよびその使用 |
| DE69941333D1 (de) * | 1998-07-02 | 2009-10-08 | Gen Probe Inc | Molekulare fackeln |
| US6207379B1 (en) * | 1998-09-11 | 2001-03-27 | One Lambda | Method for amplification of DNA |
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2010
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- 2010-08-13 CA CA2770241A patent/CA2770241C/en active Active
- 2010-08-13 CN CN2010800360045A patent/CN102471805A/zh active Pending
- 2010-08-13 WO PCT/EP2010/004963 patent/WO2011018232A1/en not_active Ceased
- 2010-08-13 ES ES10745171.8T patent/ES2608455T3/es active Active
- 2010-08-13 CN CN201710655783.0A patent/CN107254540B/zh active Active
- 2010-08-13 JP JP2012524151A patent/JP5632476B2/ja active Active
- 2010-08-13 EP EP10745171.8A patent/EP2464745B1/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| CN102471805A (zh) | 2012-05-23 |
| US8409802B2 (en) | 2013-04-02 |
| US20110039264A1 (en) | 2011-02-17 |
| US9068225B2 (en) | 2015-06-30 |
| EP2464745A1 (en) | 2012-06-20 |
| CA2770241A1 (en) | 2011-02-17 |
| ES2608455T3 (es) | 2017-04-11 |
| JP5632476B2 (ja) | 2014-11-26 |
| CN107254540B (zh) | 2021-11-16 |
| JP2013501508A (ja) | 2013-01-17 |
| EP2464745B1 (en) | 2016-11-09 |
| US20130266938A1 (en) | 2013-10-10 |
| WO2011018232A1 (en) | 2011-02-17 |
| CN107254540A (zh) | 2017-10-17 |
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