CA2761885A1 - Methods and compositions for treating lupus - Google Patents
Methods and compositions for treating lupus Download PDFInfo
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- CA2761885A1 CA2761885A1 CA2761885A CA2761885A CA2761885A1 CA 2761885 A1 CA2761885 A1 CA 2761885A1 CA 2761885 A CA2761885 A CA 2761885A CA 2761885 A CA2761885 A CA 2761885A CA 2761885 A1 CA2761885 A1 CA 2761885A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2893—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD52
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
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| PCT/US2010/034741 WO2010132683A1 (en) | 2009-05-13 | 2010-05-13 | Methods and compositions for treating lupus |
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| EP (2) | EP2429583A4 (OSRAM) |
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| MY160126A (en) | 2009-05-13 | 2017-02-28 | Genzyme Corp | Anti-human cd52 immunoglobulins |
| US20150073043A1 (en) * | 2012-01-19 | 2015-03-12 | Institut Pasteur Of Shanghai, Chinese Academy Of Sciences | Use of phosphorylation pathway-related factor in regulating function of regulatory t cell |
| JP6400604B2 (ja) * | 2013-02-08 | 2018-10-03 | アレゲーニー・シンガー リサーチ インスティチュート | プレループス診断用バイオマーカーとしての細胞結合性補体活性産物 |
| AR095199A1 (es) | 2013-03-15 | 2015-09-30 | Genzyme Corp | Anticuerpos anti-cd52 |
| CN105051544B (zh) | 2013-03-20 | 2018-11-23 | 豪夫迈·罗氏有限公司 | 小鼠血清中大鼠抗体的特异性检测 |
| PT3105317T (pt) * | 2014-02-14 | 2019-02-27 | Cellectis | Células para imunoterapia manipuladas para atuar sobre antigénios presentes tanto em células imunitárias como em células patológicas |
| KR102632082B1 (ko) * | 2015-02-27 | 2024-02-02 | 아이셀 진 테라퓨틱스 엘엘씨 | 혈액 악성종양을 표적으로 하는 키메라 항원 수용체(car), 조성물 및 이의 용도 |
| CN115058395B (zh) | 2015-06-25 | 2025-07-18 | 美商生物细胞基因治疗有限公司 | 嵌合抗原受体(car)、组合物及其使用方法 |
| US11173179B2 (en) | 2015-06-25 | 2021-11-16 | Icell Gene Therapeutics Llc | Chimeric antigen receptor (CAR) targeting multiple antigens, compositions and methods of use thereof |
| WO2017222593A1 (en) | 2016-06-24 | 2017-12-28 | Icell Gene Therapeutics Llc | Chimeric antigen receptors (cars), compositions and methods thereof |
| CN118853581A (zh) | 2017-06-21 | 2024-10-29 | 美商生物细胞基因治疗有限公司 | 嵌合抗原受体(CARs)、组合物及其使用方法 |
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| GB9022543D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Antibody production |
| GB9022547D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Purified immunoglobulin |
| GB9125768D0 (en) | 1991-12-04 | 1992-02-05 | Hale Geoffrey | Therapeutic method |
| US7119248B1 (en) | 1994-04-12 | 2006-10-10 | Miltenyi Biotec Gmbh | Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof |
| US7060802B1 (en) * | 2000-09-18 | 2006-06-13 | The Trustees Of Columbia University In The City Of New York | Tumor-associated marker |
| US7465790B2 (en) | 2000-10-09 | 2008-12-16 | Isis Innovation, Inc. | Therapeutic antibodies |
| WO2004042032A2 (en) * | 2002-11-01 | 2004-05-21 | The Ohio State University Research Foundation | Cytogenetic abnormalities that are predictive of response to therapy for chronic lymphocytic leukemia |
| US7534427B2 (en) | 2002-12-31 | 2009-05-19 | Immunomedics, Inc. | Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins |
| US20060228351A1 (en) | 2003-03-31 | 2006-10-12 | Junichi Masuyama | Method of inducing differentiation and proliferating regulatory t cell by anti-cd52 antibody and medicinal composition therefor |
| CN1898267B (zh) | 2003-11-01 | 2012-05-23 | 默克专利股份有限公司 | 修饰的抗cd52抗体 |
| CA2562771C (en) | 2004-04-12 | 2013-04-09 | Medimmune, Inc. | Anti-il-9 antibody formulations and uses thereof |
| CN101443040A (zh) * | 2006-03-16 | 2009-05-27 | 基因技术股份有限公司 | 用cd4抗体治疗狼疮的方法 |
| JP2009533350A (ja) | 2006-04-07 | 2009-09-17 | キメロス， インコーポレイテッド | Ｂ細胞悪性疾患を処置するための組成物および方法 |
| JP5541915B2 (ja) * | 2006-04-12 | 2014-07-09 | ジェンザイム・コーポレーション | 自己免疫疾患を治療する方法 |
| GB0608054D0 (en) | 2006-04-24 | 2006-05-31 | Isis Innovation | Production and use of regulatory t cells |
| CA2653848A1 (en) * | 2006-05-31 | 2007-12-06 | Genzyme Corporation | Methods of using anti-thymocyte globulin and related agents |
| AU2007275654A1 (en) | 2006-07-19 | 2008-01-24 | The Trustees Of The University Of Pennsylvania | WSX-1/p28 as a target for anti-inflammatory responses |
| US8148067B2 (en) | 2006-11-09 | 2012-04-03 | Xdx, Inc. | Methods for diagnosing and monitoring the status of systemic lupus erythematosus |
| MY160126A (en) | 2009-05-13 | 2017-02-28 | Genzyme Corp | Anti-human cd52 immunoglobulins |
| AR095199A1 (es) | 2013-03-15 | 2015-09-30 | Genzyme Corp | Anticuerpos anti-cd52 |
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| AU2010248935B2 (en) | 2016-12-15 |
| CN102438654A (zh) | 2012-05-02 |
| BRPI1013927A2 (pt) | 2016-04-05 |
| JP2015052021A (ja) | 2015-03-19 |
| RU2607022C2 (ru) | 2017-01-10 |
| US20120070408A1 (en) | 2012-03-22 |
| EP3345620B1 (en) | 2024-08-28 |
| JP2017008106A (ja) | 2017-01-12 |
| MX342907B (es) | 2016-10-17 |
| WO2010132683A1 (en) | 2010-11-18 |
| US20170369583A1 (en) | 2017-12-28 |
| JP5834004B2 (ja) | 2015-12-16 |
| AU2017201771A1 (en) | 2017-04-06 |
| KR20140014392A (ko) | 2014-02-06 |
| RU2011150495A (ru) | 2013-06-20 |
| CN110179989B (zh) | 2022-06-24 |
| IL216146A0 (en) | 2012-01-31 |
| EP2429583A1 (en) | 2012-03-21 |
| US9617343B2 (en) | 2017-04-11 |
| MX2011012048A (es) | 2011-12-12 |
| EP3345620A1 (en) | 2018-07-11 |
| AU2010248935A1 (en) | 2011-11-17 |
| JP2012526846A (ja) | 2012-11-01 |
| CN110179989A (zh) | 2019-08-30 |
| EP2429583A4 (en) | 2013-10-16 |
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