CA2747026A1 - Methods, compositions, and kits for detecting allelic variants - Google Patents
Methods, compositions, and kits for detecting allelic variants Download PDFInfo
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- CA2747026A1 CA2747026A1 CA2747026A CA2747026A CA2747026A1 CA 2747026 A1 CA2747026 A1 CA 2747026A1 CA 2747026 A CA2747026 A CA 2747026A CA 2747026 A CA2747026 A CA 2747026A CA 2747026 A1 CA2747026 A1 CA 2747026A1
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Classifications
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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| US8606527B2 (en) * | 2009-02-27 | 2013-12-10 | Bio-Rad Laboratories, Inc. | SNP detection by melt curve clustering |
| EP3249053A1 (en) | 2009-03-27 | 2017-11-29 | Life Technologies Corporation | Methods, compositions, and kits for detecting allelic variants |
| EP2494066B1 (en) * | 2009-10-27 | 2017-04-05 | Swift Biosciences, Inc. | Bimolecular primers |
| CN102115782B (zh) * | 2009-12-30 | 2014-06-18 | 北京雅康博生物科技有限公司 | 用于定量检测K-ras突变的试剂盒 |
| US20130071844A1 (en) * | 2010-03-24 | 2013-03-21 | Toppan Printing Co., Ltd. | Method for detecting target base sequence using competitive primer |
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| CN103459612A (zh) * | 2010-12-03 | 2013-12-18 | 布兰代斯大学 | 用于检测野生型群体中的核酸突变体的方法和试剂盒 |
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| CN102367478B (zh) * | 2011-10-25 | 2013-07-31 | 浙江大学 | 用于KRAS基因突变分型的ARMS-qPCR检测试剂盒及检测方法 |
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| EP2749654A1 (en) * | 2012-12-28 | 2014-07-02 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Method of analysis of composition of nucleic acid mixtures |
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| KR20160106041A (ko) * | 2013-08-14 | 2016-09-09 | 퀴아젠 맨스필드, 인코퍼레이티드 | Ｎｒａｓ 및 ｂｒａｆ 핵산의 멀티플렉스 분석을 위한 조성물 및 방법 |
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2009
- 2009-12-17 JP JP2011542142A patent/JP2012511927A/ja active Pending
- 2009-12-17 CN CN2009801557753A patent/CN102301005A/zh active Pending
- 2009-12-17 WO PCT/US2009/006652 patent/WO2010077324A2/en not_active Ceased
- 2009-12-17 US US12/641,321 patent/US9534255B2/en active Active
- 2009-12-17 CA CA2747026A patent/CA2747026A1/en not_active Withdrawn
- 2009-12-17 EP EP09836510.9A patent/EP2376659B1/en not_active Not-in-force
- 2009-12-18 WO PCT/US2009/068610 patent/WO2010080559A2/en not_active Ceased
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2015
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2018
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2020
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2022
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|---|---|
| US20160040256A1 (en) | 2016-02-11 |
| JP2012511927A (ja) | 2012-05-31 |
| WO2010077324A2 (en) | 2010-07-08 |
| US20100221717A1 (en) | 2010-09-02 |
| WO2010080559A2 (en) | 2010-07-15 |
| US20180208996A1 (en) | 2018-07-26 |
| EP2376659B1 (en) | 2015-12-02 |
| US20240132946A1 (en) | 2024-04-25 |
| EP2376659A4 (en) | 2013-01-23 |
| EP2376659A2 (en) | 2011-10-19 |
| US20200255907A1 (en) | 2020-08-13 |
| WO2010080559A3 (en) | 2010-10-28 |
| CN102301005A (zh) | 2011-12-28 |
| WO2010077324A3 (en) | 2010-10-28 |
| US10570459B2 (en) | 2020-02-25 |
| US9534255B2 (en) | 2017-01-03 |
| US11530450B2 (en) | 2022-12-20 |
| US20230323472A1 (en) | 2023-10-12 |
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