CA2737089C - Ion trap for cooling ions - Google Patents

Ion trap for cooling ions Download PDF

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Publication number
CA2737089C
CA2737089C CA2737089A CA2737089A CA2737089C CA 2737089 C CA2737089 C CA 2737089C CA 2737089 A CA2737089 A CA 2737089A CA 2737089 A CA2737089 A CA 2737089A CA 2737089 C CA2737089 C CA 2737089C
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CA
Canada
Prior art keywords
gas
ion trap
ions
axis
pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2737089A
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English (en)
French (fr)
Other versions
CA2737089A1 (en
Inventor
Alexander Makarov
Eduard Denisov
Original Assignee
Thermo Fisher Scientific Bremen GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Thermo Fisher Scientific Bremen GmbH filed Critical Thermo Fisher Scientific Bremen GmbH
Publication of CA2737089A1 publication Critical patent/CA2737089A1/en
Application granted granted Critical
Publication of CA2737089C publication Critical patent/CA2737089C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0468Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
    • H01J49/0481Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample with means for collisional cooling
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622Ion mobility spectrometry
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/004Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • H01J49/422Two-dimensional RF ion traps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CA2737089A 2008-09-23 2009-09-11 Ion trap for cooling ions Active CA2737089C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0817433.6A GB0817433D0 (en) 2008-09-23 2008-09-23 Ion trap for cooling ions
GB0817433.6 2008-09-23
PCT/EP2009/061822 WO2010034630A2 (en) 2008-09-23 2009-09-11 Ion trap for cooling ions

Publications (2)

Publication Number Publication Date
CA2737089A1 CA2737089A1 (en) 2010-04-01
CA2737089C true CA2737089C (en) 2014-05-06

Family

ID=39952083

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2737089A Active CA2737089C (en) 2008-09-23 2009-09-11 Ion trap for cooling ions

Country Status (7)

Country Link
US (1) US8642948B2 (enExample)
JP (1) JP5697259B2 (enExample)
CN (1) CN102224562B (enExample)
CA (1) CA2737089C (enExample)
DE (2) DE112009005497B4 (enExample)
GB (3) GB0817433D0 (enExample)
WO (1) WO2010034630A2 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0817433D0 (en) * 2008-09-23 2008-10-29 Thermo Fisher Scient Bremen Ion trap for cooling ions
WO2012051138A2 (en) * 2010-10-11 2012-04-19 Yale University Use of cryogenic ion chemistry to add a structural characterization capability to mass spectrometry through linear action spectroscopy
US8941054B2 (en) 2011-04-26 2015-01-27 Bruker Daltonik Gmbh Selective ion mobility spectrometer formed from two consecutive mass selective filters
GB201120307D0 (en) 2011-11-24 2012-01-04 Thermo Fisher Scient Bremen High duty cycle mass spectrometer
DE102012200211A1 (de) * 2012-01-09 2013-07-11 Carl Zeiss Nts Gmbh Vorrichtung und Verfahren zur Oberflächenbearbeitung eines Substrates
US9425033B2 (en) * 2014-06-19 2016-08-23 Bruker Daltonics, Inc. Ion injection device for a time-of-flight mass spectrometer
US10026592B2 (en) 2016-07-01 2018-07-17 Lam Research Corporation Systems and methods for tailoring ion energy distribution function by odd harmonic mixing
GB201613988D0 (en) 2016-08-16 2016-09-28 Micromass Uk Ltd And Leco Corp Mass analyser having extended flight path
GB2567794B (en) 2017-05-05 2023-03-08 Micromass Ltd Multi-reflecting time-of-flight mass spectrometers
CN110662595B (zh) 2017-05-09 2021-02-26 谱光仪器股份有限公司 四极离子阱装置及四极质谱仪
GB2563571B (en) 2017-05-26 2023-05-24 Micromass Ltd Time of flight mass analyser with spatial focussing
WO2019030475A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov MASS SPECTROMETER WITH MULTIPASSAGE
CN111164731B (zh) 2017-08-06 2022-11-18 英国质谱公司 进入多通道质谱分析仪的离子注入
WO2019030471A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov ION GUIDE INSIDE PULSED CONVERTERS
EP3662502A1 (en) 2017-08-06 2020-06-10 Micromass UK Limited Printed circuit ion mirror with compensation
US11049712B2 (en) 2017-08-06 2021-06-29 Micromass Uk Limited Fields for multi-reflecting TOF MS
US11817303B2 (en) 2017-08-06 2023-11-14 Micromass Uk Limited Accelerator for multi-pass mass spectrometers
WO2019030472A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov IONIC MIRROR FOR MULTI-REFLECTION MASS SPECTROMETERS
GB201806507D0 (en) 2018-04-20 2018-06-06 Verenchikov Anatoly Gridless ion mirrors with smooth fields
GB201807626D0 (en) * 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201807605D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201808530D0 (en) 2018-05-24 2018-07-11 Verenchikov Anatoly TOF MS detection system with improved dynamic range
GB201810573D0 (en) 2018-06-28 2018-08-15 Verenchikov Anatoly Multi-pass mass spectrometer with improved duty cycle
GB201901411D0 (en) 2019-02-01 2019-03-20 Micromass Ltd Electrode assembly for mass spectrometer
GB2583694B (en) * 2019-03-14 2021-12-29 Thermo Fisher Scient Bremen Gmbh Ion trapping scheme with improved mass range
GB201903779D0 (en) 2019-03-20 2019-05-01 Micromass Ltd Multiplexed time of flight mass spectrometer
CN110085505B (zh) * 2019-04-23 2020-06-02 中国科学院化学研究所 颗粒淌度质谱仪及颗粒的分析方法
GB2583758B (en) * 2019-05-10 2021-09-15 Thermo Fisher Scient Bremen Gmbh Improved injection of ions into an ion storage device
CN110277302B (zh) * 2019-06-28 2021-06-15 清华大学深圳研究生院 一种离子阱以及提高离子束缚效率的方法
WO2021144737A1 (en) * 2020-01-14 2021-07-22 Dh Technologies Development Pte. Ltd. High pressure mass analyzer
US11099153B1 (en) 2020-04-03 2021-08-24 Thermo Finnigan Llc Counterflow uniform-field ion mobility spectrometer
JP7409260B2 (ja) * 2020-08-19 2024-01-09 株式会社島津製作所 質量分析方法及び質量分析装置
JP7548134B2 (ja) * 2021-06-16 2024-09-10 株式会社島津製作所 質量分析装置

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2448568A (en) * 1941-03-07 1948-09-07 Zwillinger Max Apparatus and method for rectifying and projecting aerial photographs
US2463149A (en) * 1947-11-24 1949-03-01 Curtis W Caine Endotracheal intubating stylet
US4328420A (en) * 1980-07-28 1982-05-04 French John B Tandem mass spectrometer with open structure AC-only rod sections, and method of operating a mass spectrometer system
DE4202123C2 (de) 1992-01-27 1995-04-06 Bruker Franzen Analytik Gmbh Vorrichtung für die massenspektrometrische Untersuchung schneller organischer Ionen
AU6653296A (en) * 1995-08-11 1997-03-12 Mds Health Group Limited Spectrometer with axial field
GB9602158D0 (en) * 1996-02-02 1996-04-03 Graseby Dynamics Ltd Corona discharge ion sources for analytical instruments
DE19627621C2 (de) 1996-07-09 1998-05-20 Bruker Saxonia Analytik Gmbh Ionenmobilitätsspektrometer
US6911650B1 (en) * 1999-08-13 2005-06-28 Bruker Daltonics, Inc. Method and apparatus for multiple frequency multipole
DE10010204A1 (de) * 2000-03-02 2001-09-13 Bruker Daltonik Gmbh Konditionierung eines Ionenstrahls für den Einschuss in ein Flugzeitmassenspektrometer
JP2001351569A (ja) * 2000-06-02 2001-12-21 Hitachi Ltd ガス測定用オンラインモニター装置
US7087898B2 (en) * 2000-06-09 2006-08-08 Willoughby Ross C Laser desorption ion source
WO2002097857A1 (en) * 2001-05-25 2002-12-05 Analytica Of Branford, Inc. Atmospheric and vacuum pressure maldi ion source
GB2389452B (en) * 2001-12-06 2006-05-10 Bruker Daltonik Gmbh Ion-guide
DE10221468B4 (de) * 2001-12-18 2008-02-21 Bruker Daltonik Gmbh Neuartige Ionenleitsysteme
US6794642B2 (en) * 2002-08-08 2004-09-21 Micromass Uk Limited Mass spectrometer
JP4267898B2 (ja) * 2002-11-06 2009-05-27 株式会社島津製作所 質量分析装置
JP3936908B2 (ja) * 2002-12-24 2007-06-27 株式会社日立ハイテクノロジーズ 質量分析装置及び質量分析方法
JP2004259452A (ja) * 2003-02-24 2004-09-16 Hitachi High-Technologies Corp 質量分析装置及び質量分析方法
US6730904B1 (en) * 2003-04-30 2004-05-04 Varian, Inc. Asymmetric-field ion guiding devices
GB0313016D0 (en) * 2003-06-06 2003-07-09 Ms Horizons Ltd Ion extraction
WO2008007069A2 (en) * 2006-07-10 2008-01-17 Micromass Uk Limited Mass spectrometer
JP4033133B2 (ja) * 2004-01-13 2008-01-16 株式会社島津製作所 質量分析装置
GB0404106D0 (en) * 2004-02-24 2004-03-31 Shimadzu Res Lab Europe Ltd An ion trap and a method for dissociating ions in an ion trap
CN1326191C (zh) * 2004-06-04 2007-07-11 复旦大学 用印刷电路板构建的离子阱质量分析仪
US7189967B1 (en) * 2004-06-16 2007-03-13 Analytica Of Branford, Inc. Mass spectrometry with multipole ion guides
US6972408B1 (en) * 2004-09-30 2005-12-06 Ut-Battelle, Llc Ultra high mass range mass spectrometer systems
US7256395B2 (en) * 2005-01-10 2007-08-14 Applera Corporation Method and apparatus for improved sensitivity in a mass spectrometer
US7259371B2 (en) * 2005-01-10 2007-08-21 Applera Corporation Method and apparatus for improved sensitivity in a mass spectrometer
JP4506481B2 (ja) * 2005-01-20 2010-07-21 株式会社島津製作所 飛行時間型質量分析装置
GB0506288D0 (en) * 2005-03-29 2005-05-04 Thermo Finnigan Llc Improvements relating to mass spectrometry
JP4581958B2 (ja) * 2005-10-18 2010-11-17 株式会社島津製作所 質量分析装置
GB0524972D0 (en) * 2005-12-07 2006-01-18 Micromass Ltd Mass spectrometer
GB0526245D0 (en) * 2005-12-22 2006-02-01 Shimadzu Res Lab Europe Ltd A mass spectrometer using a dynamic pressure ion source
GB2439107B (en) * 2006-06-16 2011-12-14 Kratos Analytical Ltd Method and apparatus for thermalization of ions
EP2046488A4 (en) * 2006-06-29 2013-09-18 Ionwerks Inc NEUTRAL / ION REACTOR IN AN ADIABATIC ULTRASONIC GAS FLOW FOR TIME-OF-FLIGHT MASS SPECTROMETRY OF ION MOBILITIES
GB0626025D0 (en) * 2006-12-29 2007-02-07 Thermo Electron Bremen Gmbh Ion trap
JP4894916B2 (ja) * 2007-04-09 2012-03-14 株式会社島津製作所 イオントラップ質量分析装置
DE102007017055B4 (de) * 2007-04-11 2011-06-22 Bruker Daltonik GmbH, 28359 Messung der Mobilität massenselektierter Ionen
EP2136389B1 (en) * 2007-04-12 2019-12-04 Shimadzu Corporation Ion trap mass spectrometer
JP2008282594A (ja) * 2007-05-09 2008-11-20 Shimadzu Corp イオントラップ型質量分析装置
WO2009153841A1 (ja) * 2008-06-20 2009-12-23 株式会社島津製作所 質量分析装置
DE102008051695B4 (de) * 2008-09-04 2019-06-06 Bruker Daltonik Gmbh Ionenmobilitätsmessung an Potentialbarriere
GB0817433D0 (en) * 2008-09-23 2008-10-29 Thermo Fisher Scient Bremen Ion trap for cooling ions

Also Published As

Publication number Publication date
US20110163227A1 (en) 2011-07-07
GB2475826A (en) 2011-06-01
DE112009005497A5 (de) 2012-12-20
GB2475826B (en) 2013-02-27
GB201105261D0 (en) 2011-05-11
US8642948B2 (en) 2014-02-04
GB201209106D0 (en) 2012-07-04
DE112009002263T5 (de) 2011-09-29
CN102224562A (zh) 2011-10-19
CA2737089A1 (en) 2010-04-01
WO2010034630A2 (en) 2010-04-01
DE112009002263B4 (de) 2014-08-21
DE112009005497B4 (de) 2017-07-06
GB2491457B (en) 2013-04-17
WO2010034630A3 (en) 2010-05-27
CN102224562B (zh) 2016-02-10
GB0817433D0 (en) 2008-10-29
JP2012503298A (ja) 2012-02-02
JP5697259B2 (ja) 2015-04-08
GB2491457A (en) 2012-12-05

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