CA2736774A1 - Soutien nutritionnel pour prevenir et/ou attenuer la toxicite sur la moelle osseuse due a une tumeur cancereuse - Google Patents

Soutien nutritionnel pour prevenir et/ou attenuer la toxicite sur la moelle osseuse due a une tumeur cancereuse Download PDF

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Publication number
CA2736774A1
CA2736774A1 CA2736774A CA2736774A CA2736774A1 CA 2736774 A1 CA2736774 A1 CA 2736774A1 CA 2736774 A CA2736774 A CA 2736774A CA 2736774 A CA2736774 A CA 2736774A CA 2736774 A1 CA2736774 A1 CA 2736774A1
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Canada
Prior art keywords
tumor
cell
immune
bone marrow
cells
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Application number
CA2736774A
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CA2736774C (fr
Inventor
Eduardo Schiffrin
Kevin Burke Miller
Dominique Brassart
Olivier Jacques Lantz
Sebastian Diego Amigorena
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Institut Curie
Original Assignee
Nestec SA
Institut Curie
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Publication of CA2736774A1 publication Critical patent/CA2736774A1/fr
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13Nucleic acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/19Dairy proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/01Hydrolysed proteins; Derivatives thereof
    • A61K38/012Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018Hydrolysed proteins; Derivatives thereof from animals from milk
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1783Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40Transferrins, e.g. lactoferrins, ovotransferrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pediatric Medicine (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2736774A 2008-09-19 2009-09-11 Soutien nutritionnel pour prevenir et/ou attenuer la toxicite sur la moelle osseuse due a une tumeur cancereuse Active CA2736774C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9825808P 2008-09-19 2008-09-19
US61/098,258 2008-09-19
US24107409P 2009-09-10 2009-09-10
US61/241,074 2009-09-10
PCT/US2009/056599 WO2010033426A2 (fr) 2008-09-19 2009-09-11 Soutien nutritionnel pour prévenir et/ou atténuer la toxicité sur la moelle osseuse due à une tumeur cancéreuse

Publications (2)

Publication Number Publication Date
CA2736774A1 true CA2736774A1 (fr) 2010-03-25
CA2736774C CA2736774C (fr) 2017-08-22

Family

ID=41786110

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2736774A Active CA2736774C (fr) 2008-09-19 2009-09-11 Soutien nutritionnel pour prevenir et/ou attenuer la toxicite sur la moelle osseuse due a une tumeur cancereuse

Country Status (12)

Country Link
US (1) US9827216B2 (fr)
EP (2) EP2344150A2 (fr)
JP (3) JP2012502998A (fr)
CN (1) CN102215837B (fr)
AU (1) AU2009293476B2 (fr)
BR (1) BRPI0919412A8 (fr)
CA (1) CA2736774C (fr)
MX (1) MX2011002984A (fr)
MY (1) MY155635A (fr)
RU (1) RU2011115182A (fr)
WO (1) WO2010033426A2 (fr)
ZA (1) ZA201102909B (fr)

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US20150104425A1 (en) * 2006-07-24 2015-04-16 CortControl, Inc. Medical food for high cortisol breast cancer
BRPI0919412A8 (pt) 2008-09-19 2018-03-13 Inst Curie composição imunonutricional e nutricional,agente intensificador de resposta imunológica e uso do mesmo.
CN102595936A (zh) * 2009-09-25 2012-07-18 雀巢产品技术援助有限公司 包含茶氨酸和外源性核苷酸的营养组合物
JP2014510530A (ja) * 2011-03-31 2014-05-01 ネステク ソシエテ アノニム アルギニンレベルを増加させる栄養組成物及びその使用方法
WO2012141575A1 (fr) 2011-04-14 2012-10-18 N.V.Nutricia Combinaison d'epa, de dpa et/ou de dha avec un agent chimiothérapeutique
EP2876167A1 (fr) 2013-11-21 2015-05-27 Institut Gustave Roussy Composition de la flore microbienne, comme marqueur de la réceptivité à la chimiothérapie et utilisation de modulateurs microbiens (pré-, pro- ou synbiotiques) pour améliorer l'efficacité d'un traitement du cancer
US20150366941A1 (en) * 2014-06-19 2015-12-24 Cortcontrol Human disease treatment with medical food formulation
EP3317395B1 (fr) 2015-06-30 2020-07-15 Société des Produits Nestlé S.A. Composition appropriée pour protéger des micro-organismes
US10973251B1 (en) * 2015-09-21 2021-04-13 The Board Of Trustees Of The Leland Stanford Junior University Nutritional treatment for cancer
CN105943564A (zh) * 2016-04-21 2016-09-21 徐忠琴 用于胰腺癌放化疗后减轻副作用的药物组合物
CN106722972A (zh) * 2017-03-21 2017-05-31 上海中优医学检验所有限公司 针对免疫调控能力相关基因个体化配方食品及其制备方法
US11197917B2 (en) 2017-12-01 2021-12-14 ByHeart, Inc. Formulations for nutritional support in subjects in need thereof
AU2018383715A1 (en) 2017-12-11 2020-06-18 Filtricine, Inc. Compositions, methods, kits and systems for cancer treatment and metabolic intervention therapy
CN111714616A (zh) * 2019-07-17 2020-09-29 江苏西宏生物医药有限公司 一种用于抗肿瘤的组合物
JP6838752B2 (ja) * 2019-08-30 2021-03-03 株式会社東洋新薬 血流改善組成物
CN110754656A (zh) * 2019-11-07 2020-02-07 上海奥医高科技实业有限公司 一种淋巴肿瘤功能专用型临床营养配方及其制备方法
CN111840523B (zh) * 2020-08-24 2021-08-31 中国农业科学院北京畜牧兽医研究所 一种含活性蛋白和活性脂肪酸的抗癌症的药物组合物
CN114344342B (zh) * 2021-12-29 2023-06-30 广东南芯医疗科技有限公司 副干酪乳杆菌Lp. R3在制备预防或治疗肿瘤药物中的应用
WO2024163605A1 (fr) * 2023-02-01 2024-08-08 St. Jude Children's Research Hospital, Inc. Utilisation de glutamine pour le traitement du cancer et pour améliorer l'efficacité d'une immunothérapie

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AUPN271295A0 (en) 1995-05-02 1995-05-25 Gropep Pty Ltd Method of treatment
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US5438042B1 (en) * 1993-10-08 1997-08-26 Sandoz Nutrition Ltd Enteral nutritional composition having amino acid profile
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JP4664071B2 (ja) 2002-08-01 2011-04-06 エーザイ コーポレーション オブ ノース アメリカ グルタミンによるガンの改良治療
EP1675480B1 (fr) 2003-10-16 2018-06-13 Nestec S.A. Composition nutritionnelle contre les effets secondaires de la chimiotherapie ou de la radiotherapie
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JPWO2008047853A1 (ja) * 2006-10-19 2010-02-25 味の素株式会社 胃食道逆流症の予防・治療剤
BRPI0919412A8 (pt) 2008-09-19 2018-03-13 Inst Curie composição imunonutricional e nutricional,agente intensificador de resposta imunológica e uso do mesmo.

Also Published As

Publication number Publication date
JP6185500B2 (ja) 2017-08-23
CA2736774C (fr) 2017-08-22
JP2015038088A (ja) 2015-02-26
EP2344150A2 (fr) 2011-07-20
WO2010033426A2 (fr) 2010-03-25
US20110223136A1 (en) 2011-09-15
AU2009293476B2 (en) 2013-01-24
ZA201102909B (en) 2014-10-29
EP2687209A1 (fr) 2014-01-22
AU2009293476A1 (en) 2010-03-25
CN102215837B (zh) 2014-04-30
US9827216B2 (en) 2017-11-28
JP2015131829A (ja) 2015-07-23
BRPI0919412A8 (pt) 2018-03-13
MY155635A (en) 2015-11-13
CN102215837A (zh) 2011-10-12
JP2012502998A (ja) 2012-02-02
RU2011115182A (ru) 2012-10-27
BRPI0919412A2 (pt) 2015-12-15
WO2010033426A3 (fr) 2010-11-18
MX2011002984A (es) 2011-08-08

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