CA2726928A1 - Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using - Google Patents

Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using Download PDF

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Publication number
CA2726928A1
CA2726928A1 CA2726928A CA2726928A CA2726928A1 CA 2726928 A1 CA2726928 A1 CA 2726928A1 CA 2726928 A CA2726928 A CA 2726928A CA 2726928 A CA2726928 A CA 2726928A CA 2726928 A1 CA2726928 A1 CA 2726928A1
Authority
CA
Canada
Prior art keywords
seq
polypeptide
dat
monatin
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2726928A
Other languages
English (en)
French (fr)
Inventor
Mervyn L. De Souza
Paula M. Hicks
Sherry R. Kollmann
Jose M. Laplaza
Joshua M. Lundorff
Sara C. Mcfarlan
Erin Marasco
Wei Niu
Fernando A. Sanchez-Riera
Christopher Solheid
David P. Weiner
Peter Luginbuhl
Analia Bueno
Joslin Cuenca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cargill Inc
Original Assignee
Cargill Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill Inc filed Critical Cargill Inc
Publication of CA2726928A1 publication Critical patent/CA2726928A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/22Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227Tryptophan
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1096Transferases (2.) transferring nitrogenous groups (2.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2726928A 2008-01-03 2008-12-31 Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using Abandoned CA2726928A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1881408P 2008-01-03 2008-01-03
US61/018,814 2008-01-03
PCT/US2008/014137 WO2009088482A1 (en) 2008-01-03 2008-12-31 Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using

Publications (1)

Publication Number Publication Date
CA2726928A1 true CA2726928A1 (en) 2009-07-16

Family

ID=40853332

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2726928A Abandoned CA2726928A1 (en) 2008-01-03 2008-12-31 Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using

Country Status (8)

Country Link
US (1) US8785162B2 (enExample)
EP (1) EP2225390A4 (enExample)
JP (2) JP5683962B2 (enExample)
CN (1) CN101970679B (enExample)
AU (1) AU2008347048B2 (enExample)
BR (1) BRPI0822219A2 (enExample)
CA (1) CA2726928A1 (enExample)
WO (1) WO2009088482A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US20050112260A1 (en) * 2003-08-01 2005-05-26 Cargill, Inc. Monatin tabletop sweetener compositions and methods of making same
ATE360370T1 (de) * 2003-08-14 2007-05-15 Cargill Inc Monatinhaltige kaugummizusammensetzungen und verfahren zu ihrer herstellung
US20050106305A1 (en) * 2003-08-25 2005-05-19 Cargill, Inc. Beverage compositions comprising monatin and methods of making same
CN1890377B (zh) * 2003-10-21 2013-06-05 嘉吉有限公司 生产莫纳甜和莫纳甜前体
US8158389B2 (en) * 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
WO2006113897A2 (en) * 2005-04-20 2006-10-26 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US8076108B2 (en) * 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
EP2112227B1 (en) * 2006-03-07 2013-05-15 Cargill, Incorporated Aldolases, nucleic acids encoding them and methods for making and using them
US20090198072A1 (en) * 2006-05-24 2009-08-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
US10332562B2 (en) * 2007-04-17 2019-06-25 Sirius-Beta Corporation System and method for space-time annotation-capable media scrubbing
US8003361B2 (en) * 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
US8076107B2 (en) * 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
US8367847B2 (en) * 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
EP2238242B9 (en) * 2008-01-03 2015-06-10 BASF Enzymes LLC Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them
WO2012124639A1 (ja) * 2011-03-11 2012-09-20 株式会社カネカ 改変型アミノ基転移酵素、その遺伝子、およびそれらを利用した光学活性アミノ化合物の製造方法
US9029321B2 (en) 2011-03-30 2015-05-12 Board Of Regents Of The University Of Texas Methods and compositions for targeting adipose cells in mammals
HUE042206T2 (hu) * 2013-02-28 2019-06-28 Codexis Inc Módosított transzamináz polipeptidek ipari biokatalízishez
US11191555B2 (en) 2017-05-12 2021-12-07 Covidien Lp Retrieval of material from vessel lumens
CN120795059A (zh) 2018-08-27 2025-10-17 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
US10889790B2 (en) 2019-03-11 2021-01-12 Aldevron, Llc Growth of bacterial host cells in gas permeable low-density polyethylene bags for production of plasmid DNA or recombinant molecules
MX2024003753A (es) * 2021-09-29 2024-04-16 Ionis Pharmaceuticals Inc Oligonucleotidos conjugados y usos de estos.
CN114317629B (zh) * 2021-12-31 2024-08-27 山西大学 一种转氨酶连续化反应制备手性胺的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099848A (en) * 1997-11-18 2000-08-08 The Trustees Of The University Of Pennsylvania Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
CA2483126C (en) * 2002-04-23 2014-05-20 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin
WO2004085624A2 (en) * 2003-03-24 2004-10-07 Diversa Corporation Transaminases, deaminases and aminomutases and compositions and methods for enzymatic detoxification
US20050106305A1 (en) * 2003-08-25 2005-05-19 Cargill, Inc. Beverage compositions comprising monatin and methods of making same
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US7582455B2 (en) * 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
CN101490249A (zh) 2006-05-24 2009-07-22 嘉吉公司 提高平衡反应的产量的方法和系统

Also Published As

Publication number Publication date
BRPI0822219A2 (pt) 2014-11-04
WO2009088482A1 (en) 2009-07-16
US8785162B2 (en) 2014-07-22
CN101970679A (zh) 2011-02-09
AU2008347048B2 (en) 2014-06-05
JP2011508602A (ja) 2011-03-17
US20110020882A1 (en) 2011-01-27
AU2008347048A1 (en) 2009-07-16
CN101970679B (zh) 2015-04-22
JP5683962B2 (ja) 2015-03-11
JP2015091231A (ja) 2015-05-14
EP2225390A4 (en) 2012-05-09
EP2225390A1 (en) 2010-09-08

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20141231