CA2726928A1 - Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using - Google Patents

Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using Download PDF

Info

Publication number
CA2726928A1
CA2726928A1 CA2726928A CA2726928A CA2726928A1 CA 2726928 A1 CA2726928 A1 CA 2726928A1 CA 2726928 A CA2726928 A CA 2726928A CA 2726928 A CA2726928 A CA 2726928A CA 2726928 A1 CA2726928 A1 CA 2726928A1
Authority
CA
Canada
Prior art keywords
seq
polypeptide
dat
monatin
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2726928A
Other languages
English (en)
French (fr)
Inventor
Mervyn L. De Souza
Paula M. Hicks
Sherry R. Kollmann
Jose M. Laplaza
Joshua M. Lundorff
Sara C. Mcfarlan
Erin Marasco
Wei Niu
Fernando A. Sanchez-Riera
Christopher Solheid
David P. Weiner
Peter Luginbuhl
Analia Bueno
Joslin Cuenca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cargill Inc
Original Assignee
Cargill Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill Inc filed Critical Cargill Inc
Publication of CA2726928A1 publication Critical patent/CA2726928A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2726928A 2008-01-03 2008-12-31 Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using Abandoned CA2726928A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1881408P 2008-01-03 2008-01-03
US61/018,814 2008-01-03
PCT/US2008/014137 WO2009088482A1 (en) 2008-01-03 2008-12-31 Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using

Publications (1)

Publication Number Publication Date
CA2726928A1 true CA2726928A1 (en) 2009-07-16

Family

ID=40853332

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2726928A Abandoned CA2726928A1 (en) 2008-01-03 2008-12-31 Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using

Country Status (8)

Country Link
US (1) US8785162B2 (enExample)
EP (1) EP2225390A4 (enExample)
JP (2) JP5683962B2 (enExample)
CN (1) CN101970679B (enExample)
AU (1) AU2008347048B2 (enExample)
BR (1) BRPI0822219A2 (enExample)
CA (1) CA2726928A1 (enExample)
WO (1) WO2009088482A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
EP1648248A2 (en) * 2003-08-01 2006-04-26 Cargill, Incorporated Monatin tabletop sweetener compositions and methods of making same
KR101194132B1 (ko) * 2003-08-14 2012-10-25 카아길, 인코포레이팃드 모나틴을 포함하는 추잉검 조성물 및 이의 제조 방법
US20050106305A1 (en) * 2003-08-25 2005-05-19 Cargill, Inc. Beverage compositions comprising monatin and methods of making same
US8206955B2 (en) * 2003-10-21 2012-06-26 Cargill, Incorporated Production of monatin and monatin precursors
EP1883817A4 (en) * 2005-04-20 2009-09-23 Cargill Inc PRODUCTS AND PROCEDURES FOR IN VIVO SECRETION OF MONATIN
US8158389B2 (en) * 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
ES2416104T3 (es) 2006-03-07 2013-07-30 Cargill, Incorporated Aldolasas, ácidos nucleicos que las codifican y métodos para producir y usar las mismas
US20090198072A1 (en) * 2006-05-24 2009-08-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
US10332562B2 (en) * 2007-04-17 2019-06-25 Sirius-Beta Corporation System and method for space-time annotation-capable media scrubbing
US8076107B2 (en) * 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
US8367847B2 (en) * 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
US8003361B2 (en) * 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
AU2008347234B2 (en) * 2008-01-03 2015-05-28 Basf Enzymes Llc Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them
CN103534353B (zh) * 2011-03-11 2016-08-17 株式会社钟化 修饰型氨基转移酶、其基因以及利用它们的光学活性氨基化合物的制造方法
CA2830375A1 (en) 2011-03-30 2012-10-04 Board Of Regents Of The University Of Texas System Methods and compositions for targeting adipose cells in mammals
US9617573B2 (en) * 2013-02-28 2017-04-11 Codexis, Inc. Engineered transaminase polypeptides for industrial biocatalysis
US11191555B2 (en) 2017-05-12 2021-12-07 Covidien Lp Retrieval of material from vessel lumens
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
WO2020185971A1 (en) 2019-03-11 2020-09-17 Aldevron, Llc Growing bacterial host cells in gas-permeable low-density polyethylene bags to produce plasmid dna or recombinant molecules
KR20240067118A (ko) * 2021-09-29 2024-05-16 아이오니스 파마수티컬즈, 인코포레이티드 접합된 올리고뉴클레오타이드 및 이의 용도
CN114317629B (zh) * 2021-12-31 2024-08-27 山西大学 一种转氨酶连续化反应制备手性胺的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099848A (en) * 1997-11-18 2000-08-08 The Trustees Of The University Of Pennsylvania Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use
PL208481B1 (pl) * 2002-04-23 2011-05-31 Cargill Sposób wytwarzania monatyny
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
WO2004085624A2 (en) * 2003-03-24 2004-10-07 Diversa Corporation Transaminases, deaminases and aminomutases and compositions and methods for enzymatic detoxification
US20050106305A1 (en) * 2003-08-25 2005-05-19 Cargill, Inc. Beverage compositions comprising monatin and methods of making same
US7582455B2 (en) * 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US8076108B2 (en) * 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
JP2009538145A (ja) * 2006-05-24 2009-11-05 カーギル・インコーポレイテッド 平衡反応の収量を増加させるための方法およびシステム

Also Published As

Publication number Publication date
AU2008347048B2 (en) 2014-06-05
EP2225390A4 (en) 2012-05-09
US8785162B2 (en) 2014-07-22
US20110020882A1 (en) 2011-01-27
JP2011508602A (ja) 2011-03-17
AU2008347048A1 (en) 2009-07-16
EP2225390A1 (en) 2010-09-08
JP2015091231A (ja) 2015-05-14
BRPI0822219A2 (pt) 2014-11-04
WO2009088482A1 (en) 2009-07-16
CN101970679B (zh) 2015-04-22
CN101970679A (zh) 2011-02-09
JP5683962B2 (ja) 2015-03-11

Similar Documents

Publication Publication Date Title
AU2008347048B2 (en) Aminotransferase and oxidoreductase nucleic acids and polypeptides and methods of using
US7582455B2 (en) Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
JP5139267B2 (ja) モナチン及びその前駆体の生成のためのポリペプチド及び生合成経路
JP7436450B2 (ja) L-グルタミン酸脱水素酵素突然変異体及びその使用
JP4532116B2 (ja) アラニン2,3−アミノムターゼ
EP2089529B1 (en) Production of stereoisomers of monatin via d-tryptophan
JP2005523696A (ja) ポリペプチド及び生合成経路
US20110045547A1 (en) Isomerases and epimerases and methods of using
EP2361976B1 (en) Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
KR20120068872A (ko) 모나틴의 제조 방법
WO2009088442A2 (en) Isomerases and epimerases and methods of using
AU2012201740B2 (en) Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
JP2021101628A (ja) アミノ安息香酸類水酸化反応の評価方法

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20141231