CA2725618C - Antiviral salts - Google Patents

Antiviral salts Download PDF

Info

Publication number
CA2725618C
CA2725618C CA2725618A CA2725618A CA2725618C CA 2725618 C CA2725618 C CA 2725618C CA 2725618 A CA2725618 A CA 2725618A CA 2725618 A CA2725618 A CA 2725618A CA 2725618 C CA2725618 C CA 2725618C
Authority
CA
Canada
Prior art keywords
salt
compound
acid
formula
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2725618A
Other languages
English (en)
French (fr)
Other versions
CA2725618A1 (en
Inventor
Jane Ryan
Margaret Anne Butt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biota Scientific Management Pty Ltd
Original Assignee
Biota Scientific Management Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scientific Management Pty Ltd filed Critical Biota Scientific Management Pty Ltd
Publication of CA2725618A1 publication Critical patent/CA2725618A1/en
Application granted granted Critical
Publication of CA2725618C publication Critical patent/CA2725618C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA2725618A 2008-05-27 2009-05-27 Antiviral salts Expired - Fee Related CA2725618C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5634108P 2008-05-27 2008-05-27
US61/056,341 2008-05-27
PCT/AU2009/000663 WO2009143571A1 (en) 2008-05-27 2009-05-27 Antiviral salts

Publications (2)

Publication Number Publication Date
CA2725618A1 CA2725618A1 (en) 2009-12-03
CA2725618C true CA2725618C (en) 2016-04-12

Family

ID=41376478

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2725618A Expired - Fee Related CA2725618C (en) 2008-05-27 2009-05-27 Antiviral salts

Country Status (14)

Country Link
US (2) US8580791B2 (enExample)
EP (1) EP2297141B1 (enExample)
JP (1) JP5469662B2 (enExample)
KR (1) KR20110019759A (enExample)
CN (1) CN102046621B (enExample)
AU (1) AU2009253738B2 (enExample)
BR (1) BRPI0912038A2 (enExample)
CA (1) CA2725618C (enExample)
CO (1) CO6280534A2 (enExample)
EA (1) EA020455B1 (enExample)
MX (1) MX2010013019A (enExample)
NZ (1) NZ590286A (enExample)
WO (1) WO2009143571A1 (enExample)
ZA (1) ZA201009284B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG184430A1 (en) 2010-04-15 2012-11-29 Biota Scient Management Compound for treatment of respiratory condition or disease
EP2585067B1 (en) * 2010-06-25 2017-08-09 Biota Scientific Management Pty Ltd Compound for the treatment of enteroviruses
CN102617462B (zh) * 2012-02-28 2014-02-12 南京大学 特异性抑制肌肉微小核糖核酸的化合物及其合成方法和应用
BR112016029942A2 (pt) * 2014-06-20 2017-08-22 Aviragen Therapeutics Inc composto, forma de base livre cristalina anidra, composição farmacêutica, método para fabricação de uma forma de base livre cristalina, método de tratamento de uma infecção viral, método de tratar, aliviar, prevenir ou reduzir os sintomas ou exacerbações de asma ou doença pulmonar obstrutiva crônica e método de tratamento de doença mão, pé e boca
CA3216679A1 (en) * 2021-05-05 2022-11-10 George R. Painter Nucleotide and nucleoside therapeutic compositions, combinations and uses related thereto
WO2024192151A2 (en) * 2023-03-13 2024-09-19 Altesa BioSciences, Inc. Method of dosing vapendavir to treat enterovirus infections

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1170387B (it) 1982-06-07 1987-06-03 Glaxo Group Ltd Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
GB2162522B (en) 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB9026998D0 (en) 1990-12-12 1991-01-30 Glaxo Group Ltd Medicaments
US5514778A (en) * 1993-07-01 1996-05-07 Eli Lilly And Company Anti-picornaviral agents
US5545653A (en) * 1995-06-07 1996-08-13 Eli Lilly And Company Anti-viral compounds
US5693661A (en) * 1995-06-07 1997-12-02 Eli Lilly And Company Anti-viral compounds
US5891874A (en) * 1996-06-05 1999-04-06 Eli Lilly And Company Anti-viral compound
US5821242A (en) * 1996-06-06 1998-10-13 Eli Lilly And Company Anti-viral compounds
AU6031898A (en) * 1997-01-22 1998-08-07 Eli Lilly And Company Anti-viral compounds
EP1001767A4 (en) * 1997-06-04 2001-07-04 Lilly Co Eli ANTIVIRAL CONNECTIONS
US6358971B1 (en) * 1998-05-20 2002-03-19 Eli Lilly And Company Anti-viral compounds
TR200003414T2 (tr) * 1998-05-20 2001-03-21 Eli Lilly And Company Anti-viral terkipler
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents

Also Published As

Publication number Publication date
WO2009143571A1 (en) 2009-12-03
EP2297141A1 (en) 2011-03-23
CO6280534A2 (es) 2011-05-20
US20140179710A1 (en) 2014-06-26
ZA201009284B (en) 2012-06-27
AU2009253738A1 (en) 2009-12-03
EA201001835A1 (ru) 2011-06-30
CA2725618A1 (en) 2009-12-03
JP2011520991A (ja) 2011-07-21
EP2297141A4 (en) 2012-04-25
CN102046621A (zh) 2011-05-04
AU2009253738B2 (en) 2012-12-13
CN102046621B (zh) 2014-11-12
MX2010013019A (es) 2011-03-21
BRPI0912038A2 (pt) 2017-06-20
EA020455B1 (ru) 2014-11-28
US9206171B2 (en) 2015-12-08
JP5469662B2 (ja) 2014-04-16
NZ590286A (en) 2011-08-26
KR20110019759A (ko) 2011-02-28
EP2297141B1 (en) 2015-10-21
US20110144118A1 (en) 2011-06-16
US8580791B2 (en) 2013-11-12

Similar Documents

Publication Publication Date Title
TWI815396B (zh) 具有病毒增殖抑制作用之三嗪衍生物及含有其等之醫藥組合物
TWI786110B (zh) (s)-2-乙基丁基2-(((s)-(((2r,3s,4r,5r) -5-(4-胺基吡咯并[2,1-f][1,2,4]三嗪-7-基)-5-氰基-3,4-二羥基四氫呋喃-2-基)甲氧基)(苯氧基)磷醯基)胺基)丙酸酯之結晶形式
CA2716914C (en) Novel crystalline forms of trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide sodium salt
US9206171B2 (en) 6-{2 -[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy}-3-ethoxy-1,2-benzisoxazole bis-dihydrogenphosphate salt (1:2)
US12410189B2 (en) Polymorphs and solid forms of (S)-2-2((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9- yl)amino)propanamide, and methods of production
JP2014169270A (ja) (1s,2s,3s,4r)−3−[(1s)−1−アセチルアミノ−2−エチル−ブチル]−4−グアニジノ−2−ヒドロキシ−シクロペンチル−1−カルボン酸水和物の製造方法
EA016904B1 (ru) Новый холиновый сокристалл эпалрестата
JP2022530441A (ja) 7h-ピロロ[2,3-d]ピリミジンjak-阻害剤
TWI496773B (zh) N-[2-[[(2,3-二氟苯基)甲基]硫基]-6-{[(1r,2s)-2,3-二羥基-1-甲基丙基]氧基}-4-嘧啶基]-1-三亞甲亞胺磺醯胺之新穎結晶型
TWI889708B (zh) 1,3,5-三衍生物或其溶劑合物之結晶及其製造方法
CN115279752A (zh) Taar1激动剂的盐和结晶形式
EA018600B1 (ru) Новые кристаллические соли эпалрестата
US8772488B2 (en) Crystals of prasugrel hydrobromate
RU2712226C2 (ru) Фениламинопиримидин или полиморфная форма соли фениламинопиримидина
JP4940152B2 (ja) パモ酸オランザピン二水和物
CN114853762A (zh) 一种咪唑并三嗪类化合物的固体形式及其制备方法和用途
US9464086B2 (en) Crystalline forms of N,N-dicyclopropyl-4-(1,5-dimethyl-1 H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-D]pyrrolo[2,3-B]pyridine-7-carboxamide for the treatment of myeloproliferative disorders
CN116761612A (zh) α-1062葡糖酸盐的固体形式
CN102408375B (zh) 奥扎格雷钠化合物
WO2009087151A1 (en) Polymorphic forms of moxifloxacin hydrochloride and processes for preparation thereof
JP2020522472A (ja) Pkc阻害剤の固体状態形態
KR20250130617A (ko) 스피로고리 화합물의 결정 및 이의 제조 방법

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140219

MKLA Lapsed

Effective date: 20190527