CA2725601A1 - Supercharged proteins for cell penetration - Google Patents
Supercharged proteins for cell penetration Download PDFInfo
- Publication number
- CA2725601A1 CA2725601A1 CA2725601A CA2725601A CA2725601A1 CA 2725601 A1 CA2725601 A1 CA 2725601A1 CA 2725601 A CA2725601 A CA 2725601A CA 2725601 A CA2725601 A CA 2725601A CA 2725601 A1 CA2725601 A1 CA 2725601A1
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- Prior art keywords
- protein
- lys
- supercharged
- complex
- supercharged protein
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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| PCT/US2009/041984 WO2009134808A2 (en) | 2008-04-28 | 2009-04-28 | Supercharged proteins for cell penetration |
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| PT2371855E (pt) * | 2005-08-05 | 2015-11-03 | Araim Pharmaceuticals Inc | Péptidos protetores de tecidos e suas utilizações |
| EP3045532A1 (en) | 2006-06-02 | 2016-07-20 | President and Fellows of Harvard College | Protein surface remodeling |
| KR101722961B1 (ko) | 2009-02-11 | 2017-04-04 | 알부메딕스 에이/에스 | 알부민 변이체 및 접합체 |
| JP2012525146A (ja) * | 2009-04-28 | 2012-10-22 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 細胞透過のための過剰に荷電されたタンパク質 |
| MX2012004793A (es) | 2009-10-30 | 2012-07-20 | Novozymes Biopharma Dk As | Variantes de albumina. |
| JP5969458B2 (ja) | 2010-04-09 | 2016-08-17 | アルブミディクス アクティーゼルスカブ | アルブミン誘導体及び変異体 |
| CA2807552A1 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
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-
2009
- 2009-04-28 CA CA2725601A patent/CA2725601A1/en not_active Abandoned
- 2009-04-28 CN CN200980123772.1A patent/CN102066405B/zh not_active Expired - Fee Related
- 2009-04-28 US US12/989,829 patent/US20110112040A1/en not_active Abandoned
- 2009-04-28 WO PCT/US2009/041984 patent/WO2009134808A2/en not_active Ceased
- 2009-04-28 JP JP2011507588A patent/JP2011523353A/ja active Pending
- 2009-04-28 EP EP09739610A patent/EP2297182A4/en not_active Withdrawn
- 2009-04-28 AU AU2009243187A patent/AU2009243187C1/en not_active Ceased
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2014
- 2014-06-03 JP JP2014114885A patent/JP2014159484A/ja active Pending
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| Publication number | Publication date |
|---|---|
| AU2009243187C1 (en) | 2015-12-24 |
| AU2009243187B2 (en) | 2015-09-17 |
| JP2011523353A (ja) | 2011-08-11 |
| WO2009134808A3 (en) | 2010-06-10 |
| EP2297182A2 (en) | 2011-03-23 |
| AU2009243187A1 (en) | 2009-11-05 |
| EP2297182A4 (en) | 2012-08-15 |
| US20110112040A1 (en) | 2011-05-12 |
| AU2009243187B9 (en) | 2015-11-12 |
| JP2014159484A (ja) | 2014-09-04 |
| CN102066405A (zh) | 2011-05-18 |
| WO2009134808A2 (en) | 2009-11-05 |
| CN102066405B (zh) | 2015-09-30 |
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